Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Firas Obaid Arhema Frejat"'
Autor:
Firas Obaid Arhema Frejat, Yaquan Cao, Hongjin Zhai, Salah A. Abdel-Aziz, Hesham A.M. Gomaa, Bahaa G.M. Youssif, Chunli Wu
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 1, Pp 103538- (2022)
DNA gyrase is a promising target for antibacterial agents. Several classes of small-molecule inhibitors have been discovered in recent decades, but none of these have reached the market. We have designed a small library of 1,2,4-oxadiazole/pyrrolidin
Externí odkaz:
https://doaj.org/article/120d5a647ab344a98570653092417f49
Autor:
Firas Obaid Arhema Frejat, Hongjin Zhai, Yaquan Cao, Lihong Wang, Yaser A. Mostafa, Hesham A.M. Gomaa, Bahaa G.M. Youssif, Chunli Wu
Publikováno v:
Bioorganic chemistry. 126
Indazole is a significant class of heterocyclic compounds with a wide range of biological activity. We display here the synthesis and biological evaluation of a novel series of indazole derivatives 6a-v, which are differently substituted at the 6-pos
Autor:
Yaquan Cao, Yingxue Yang, Maxwell Ampomah-Wireko, Firas Obaid Arhema Frejat, Hongjin Zhai, Shuo Zhang, Huanhuan Wang, Pu Yang, Qingyan Yuan, Guanlian Wu, Chunli Wu
Publikováno v:
Bioorganicmedicinal chemistry letters. 64
In this study, a novel batch of indazole containing 1,2,3-triazole agents were designed and synthesized. The antiproliferative activity of target compounds in four human cancer cells, PC-3 (human prostate cancer cell), MCF-7 (human breast cancer cell
Autor:
Yaquan Cao, Firas Obaid Arhema Frejat, Hesham A.M. Gomaa, Hongjin Zhai, Salah A. Abdel-Aziz, Chunli Wu, Bahaa G.M. Youssif
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 1, Pp 103538-(2022)
DNA gyrase is a promising target for antibacterial agents. Several classes of small-molecule inhibitors have been discovered in recent decades, but none of these have reached the market. We have designed a small library of 1,2,4-oxadiazole/pyrrolidin
Publikováno v:
HETEROCYCLES. 94:1903