Phenotype of limited cutaneous systemic sclerosis patients with positive anti-topoisomerase I antibodies: data from the EUSTAR cohort

Autor: Elisabetta Zanatta 1, Dörte Huscher 2, Augusta Ortolan 1, Jérôme Avouac 3, Paolo Airò 4, Alexandra Balbir-Gurman 5, Elise Siegert 6, Marco Matucci Cerinic 7, Franco Cozzi 8, Gabriela Riemekasten 9, Anna-Maria Hoffmann-Vold 10, Oliver Distler 11, Armando Gabrielli 12, Stefan Heitmann 13, Nicolas Hunzelmann 14, Carlomaurizio Montecucco 15, Jadranka Morovic-Vergles 16, Camillo Ribi 17, Andrea Doria 1, Yannick Allanore 3, EUSTAR collaborators, Giovanna Cuomo, Gianluca Moroncini, Jiri Stork, Fiorenzo Iannone, Ulrich Walker, Eugenia Bertoldo, Dorota Krasowska, Maria João Salvador, Mohammed Tikly, Eric Hachulla, Valeria Riccieri, Ami Sha, Ana Maria Gheorghiu, Cord Sunderkötter, Francesca Ingegnoli, Luc Mouthon, Vanessa Smith, Francesco Paolo Cantatore, Kilian Eyerich, Piotr Wiland, Marie Vanthuyne, Branimir Anic, Maria Üprus, Brigitte Granel, Alessandra Vacca, Cristina-Mihaela Tanaseanu, Paloma García de la Peña Lefebvre, Jean Sibilia, Ira Litinsky, Lesley Ann Saketkoo, Eduardo Kerzberg, Massimiliano Limonta, Doron Rimar, Petros Sfikakis, Maurizio Cutolo, Patricia E Carreira, Rosario Foti, Srdan Novak, Michele Iudici, Mislav Radic, Raffaele Pellerito, Carlo Francesco Selmi, Lidia P Ananieva, Gabriela Szücs, Carlos de la Puente, Ruxandra Maria Ionescu, Jörg Distler, Maria Rosa Pozzi, Juan Jose Alegre-Sancho, Kristine Herrmann, Ellen De Langhe, Sule Yavuz, Carolina de Souza Müller, Svetlana Agachi, Douglas Veale, Esthela Loyo, Mengtao Li, Edoardo Rosato, Britta Maurer, Ivan Castellví, François Spertini, Kamal Solanki, Nicoletta Del Papa, Gerard Espinosa, László Czirják, Bernard Coleiro, Dominique Farge Bancel, Christopher Denton, Nemanja Damjanov, Jörg Henes, Vera Ortiz Santamaria, Michaela Kohm, Bojana Stamenkovic

Publikováno v: Rheumatology. 61:4786-4796

Objectives To characterize patients with positive anti-topoisomerase I (ATA) in lcSSc. Methods SSc patients enrolled in the EUSTAR cohort with a disease duration of ≤3 years at database entry were considered. We assessed the risk of major organ inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ed7982c4b3dd090ba0e34399adfe64
https://doi.org/10.1093/rheumatology/keac188

Predictors of ASDAS Inactive Disease in Axial Spondyloarthritis During Treatment with TNF-Inhibitors: Data from the Eurospa Collaboration

Autor: Lykke M. Ørnbjerg, Louise Linde, Stylianos Georgiadis, Simon H. Rasmussen, Ulf Lindström, Johan Askling, Brigitte Michelsen, Daniela Di Giuseppe, Johan K. Wallman, Karel Pavelka, Jakub Závada, Michael J. Nissen, Gareth T. Jones, Heikki Relas, Laura Pirilä, Matija Tomšič, Ziga Rotar, Arni Jon Geirsson, Bjorn Gudbjornsson, Eirik K. Kristianslund, Irene E. van der Horst-Bruinsma, Anne Gitte Loft, Karin Laas, Fiorenzo Iannone, Addolorata Corrado, Adrian Ciurea, Maria J. Santos, Helena Santos, Catalin Codreanu, Nurullah Akkoc, Ozgul S. Gunduz, Bente Glintborg, Mikkel Østergaard, Merete Lund Hetland

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f203cbbf348a09f6871554330dd46868
https://doi.org/10.2139/ssrn.4081889

An Italian Multicenter Study on Anti-NXP2 Antibodies: Clinical and Serological Associations

Autor: Micaela, Fredi, Ilaria, Cavazzana, Angela, Ceribelli, Lorenzo, Cavagna, Simone, Barsotti, Elena, Bartoloni, Maurizio, Benucci, Ludovico, De Stefano, Andrea, Doria, Giacomo, Emmi, Martina, Fabris, Marco, Fornaro, Federica, Furini, Maria Grazia, Giudizi, Marcello, Govoni, Anna, Ghirardello, Luca, Iaccarino, Fiorenzo, Iannone, Maria, Infantino, Natasa, Isailovic, Maria Grazia, Lazzaroni, Mariangela, Manfredi, Alessandro, Mathieu, Emiliano, Marasco, Paola, Migliorini, Carlomaurizio, Montecucco, Boaz, Palterer, Paola, Parronchi, Matteo, Piga, Federico, Pratesi, Valeria, Riccieri, Carlo, Selmi, Marilina, Tampoia, Alessandra, Tripoli, Giovanni, Zanframundo, Antonella, Radice, Roberto, Gerli, Franco, Franceschini

Publikováno v: Clinical reviews in allergyimmunology. 63(2)

The identification of anti-NXP2 antibodies is considered a serological marker of dermatomyositis (DM), with calcinosis, severe myositis and, in some reports, with cancer. Historically, these associations with anti-NXP2 antibodies have been detected b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef96688582f5796d8c3a0aa426575275
https://pubmed.ncbi.nlm.nih.gov/35092577

The evaluation of myocarditis in patients with Still's disease; clinical findings from the multicentre international AIDA Network Still's Disease Registry.

Autor: Ruscitti P; Piero Ruscitti, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Di Cola I; Ilenia Di Cola, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Vitale A; Antonio Vitale, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Caggiano V; Valeria Caggiano, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Palumbo P; Pierpaolo Palumbo, Department of Diagnostic Imaging, Area of Cardiovascular and Interventional Imaging, Abruzzo Health Unit 1, L'Aquila, Italy., Di Cesare E; Ernesto Di Cesare, Department of Diagnostic Imaging, Area of Cardiovascular and Interventional Imaging, Abruzzo Health Unit 1, L'Aquila, Italy., Torres-Ruiz J; Jiram Torres-Ruiz, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Guaracha-Basañez GA; Guillermo Arturo Guaracha-Basañez, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Martín-Nares E; Eduardo Martín-Nares, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Ciccia F; Francesco Ciccia, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Iacono D; Daniela Iacono, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Riccio F; Flavia Riccio, Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Maggio MC; Maria Cristina Maggio, University Department of Health Promotion, Mother and Child Care, Internal Medicine Italy., Tharwat S; Samar Tharwat, Rheumatology and Immunology Unit, Internal Medicine Department, Mansoura University, Mansoura, Egypt; Department of Internal Medicine, Faculty of Medicine, Horus University, New Damietta, Egypt., Hashad S; Soad Hashad, Rheumatology Department, Tripoli Children Hospital, Tripoli, Libya., Rigante D; Donato Rigante, Department of Life Sciences and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Università Cattolica Sacro Cuore, Rome, Italy., Ortolan A; Augusta Ortolan, Rheumatology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Giardini HAM; Henrique A. Mayrink Giardini, Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., Parente de Brito Antonelli I; Isabele Parente de Brito Antonelli, Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., Cordeiro RA; Rafael Alves Cordeiro, Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., Giacomelli R; Roberto Giacomelli, Clinical and research section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Bio-Medico, Via Álvaro del Portillo , Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy.0, 001, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy; Rheumatology, Immunology and Clinical Medicine Unit, Department of Medicine, University of Rome 'Campus Biomedico' School of Medicine, Rome, Italy., Navarini L; Luca Navarini, Clinical and research section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Bio-Medico, Via Álvaro del Portillo , Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy.0, 001, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy; Rheumatology, Immunology and Clinical Medicine Unit, Department of Medicine, University of Rome 'Campus Biomedico' School of Medicine, Rome, Italy., Berardicurti O; Onorina Berardicurti, Clinical and research section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Bio-Medico, Via Álvaro del Portillo , Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy.0, 001, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy; Rheumatology, Immunology and Clinical Medicine Unit, Department of Medicine, University of Rome 'Campus Biomedico' School of Medicine, Rome, Italy., Conforti A; Alessandro Conforti, U.O. Medicina Generale, Ospedale San Paolo di Civitavecchia, ASL Roma 4, Civitavecchia, Rome, Italy., Opris-Belinski D; Daniela Opris-Belinski, Rheumatology and Internal Medicine Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania., Sota J; Jurgen Sota, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Gaggiano C; Carla Gaggiano, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Lopalco G; Giuseppe Lopalco, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J) Policlinic Hospital, University of Bari, Bari, Italy., Iannone F; Fiorenzo Iannone, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J) Policlinic Hospital, University of Bari, Bari, Italy., La Torre F; Francesco La Torre, Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy., Mastrorilli V; Violetta Mastrorilli, Department of Pediatrics, Pediatric Rheumatology Center, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy., Govoni M; Marcello Govoni, Rheumatology Unit, Department of Medical Sciences, Azienda Ospedaliero-Universitaria S. Anna-Ferrara, University of Ferrara, Ferrara, Italy., Ruffilli F; Francesca Ruffilli, Rheumatology Unit, Department of Medical Sciences, Azienda Ospedaliero-Universitaria S. Anna-Ferrara, University of Ferrara, Ferrara, Italy., Emmi G; Giacomo Emmi, Department of Medical, Surgical and Health Sciences, University of Trieste, Italy, and Clinical Medicine and Rheumatology Unit, Cattinara University Hospital, Trieste, Italy.; Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical entre, Melbourne, Australia., Biancalana E; Edoardo Biancalana, Department of Experimental and Clinical Medicine, Florence, Italy., Sfikakis PP; Petros P. Sfikakis, Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Tektonidou M; Maria Tektonidou, Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Hernández-Rodríguez J; José Hernández-Rodríguez, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain., Gómez-Caverzaschi V; Verónica Gómez-Caverzaschi, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain., Gündüz ÖS; Özgül Soysal Gündüz, Department of Internal Medicine, Division of Rheumatology, Celal Bayar University School of Medicine, Manisa, Turkey., Conti G; Giovanni Conti, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy., Patroniti S; Serena Patroniti, Pediatric Nephrology and Rheumatology Unit, Azienda Ospedaliera Universitaria (AOU), 'G. Martino' Messina, Italy., Gidaro A; Antonio Gidaro, Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy., Bartoli A; Arianna Bartoli, Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy., Olivieri AN; Alma Nunzia Olivieri, Department of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy., Gicchino MF; M. Francesca Gicchino, Department of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy., Brucato AL; Antonio Luca Brucato, Pediatric Unit, Fatebenefratelli Hospital, Milan, Italy., Dagna L; Lorenzo Dagna, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Tomelleri A; Alessandro Tomelleri, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Campochiaro C; Corrado Campochiaro, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., De Paulis A; Amato De Paulis, Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy; Center for Basic and Clinical Immunology Research (CISI), WAO Center of Excellence, University of Naples Federico II, Naples, Italy., Mormile I; Ilaria Mormile, Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy., Della Casa F; Francesca Della Casa, Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy., Direskeneli H; Haner Direskeneli, Department of Internal Medicine, Division of Rheumatology, Marmara University, Faculty of Medicine, Istanbul, Turkey., Alibaz-Oner F; Fatma Alibaz-Oner, Department of Internal Medicine, Division of Rheumatology, Marmara University, Faculty of Medicine, Istanbul, Turkey., Karamanakos A; Anastasios Karamanakos, Department of Rheumatology, 'Evangelismos' General Hospital, Athens, Greece., Dimouli A; Aikaterini Dimouli, Department of Rheumatology, 'Evangelismos' General Hospital, Athens, Greece., Ragab G; Gaafar Ragab, Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Giza, Egypt; Faculty of Medicine, Newgiza University, 6th of October City, Egypt., Mahmoud Ahmed AA; Ayman Abdelmonem Ahmed Mahmoud, Rheumatology and Clinical Immunology Unit, Internal Medicine Department, Faculty of Medicine, Cairo University, Giza, Egypt., Tufan A; Abdurrahman Tufan, Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey., Kucuk H; Hamit Kucuk, Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey., Kardas R; Riza Kardas, Gazi University Hospital, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey., Batu ED; Ezgi D. Batu, Department of Pediatric Rheumatology, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Ozen S; Seza Ozen, Department of Pediatric Rheumatology, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Wiesik-Szewczyk E; Ewa Wiesik-Szewczyk, Department of Internal Medicine, Pneumonology, Allergology and Clinical Immunology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine, National Research Institute, Warsaw, Poland., Hinojosa-Azaola A; Andrea Hinojosa-Azaola, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Balistreri A; Alberto Balistreri, Bioengineering and Biomedical Data Science Lab, Department ofMedical Biotechnologies, University of Siena, Siena, Italy, Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Fabiani C; Claudia Fabiani, Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Frediani B; Bruno Frediani, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Cantarini L; Luca Cantarini, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.

Publikováno v: The Journal of rheumatology [J Rheumatol] 2024 Nov 15. Date of Electronic Publication: 2024 Nov 15.