Zobrazeno 1 - 10 of 145 pro vyhledávání: '"Fiorenza, Viani"'
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Synthesis and Conformational Analysis of Hydantoin-Based Universal Peptidomimetics
Autor: Alessio M. Caramiello, Maria Cristina Bellucci, Gaetano Cristina, Carlo Castellano, Fiorella Meneghetti, Matteo Mori, Francesco Secundo, Fiorenza Viani, Alessandro Sacchetti, Alessandro Volonterio
Publikováno v: The Journal of organic chemistry.
The synthesis of a collection of enantiomerically pure, systematically substituted hydantoins as structural privileged universal mimetic scaffolds is presented. It relies on a chemoselective condensation/cyclization domino process between isocyanates
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9752c1b85bdd6e8a075e9587086111
https://pubmed.ncbi.nlm.nih.gov/36226862
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3
Multifunctional Neomycin-Triazine-Based Cationic Lipids for Gene Delivery with Antibacterial Properties
Autor: Federica Ponti, Chiara Pennetta, Maria Cristina Bellucci, Fiorenza Viani, Gabriele Candiani, Alessandro Volonterio, Nina Bono
Publikováno v: Bioconjugate chemistry (2021). doi:10.1021/acs.bioconjchem.0c00616
info:cnr-pdr/source/autori:Pennetta C.; Bono N.; Ponti F.; Bellucci M.C.; Viani F.; Candiani G.; Volonterio A./titolo:Multifunctional Neomycin-Triazine-Based Cationic Lipids for Gene Delivery with Antibacterial Properties/doi:10.1021%2Facs.bioconjchem.0c00616/rivista:Bioconjugate chemistry/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume
Bioconjugate Chemistry
Cationic lipids (CLs) have gained significant attention among nonviral gene delivery vectors due to their ease of synthesis and functionalization with multivalent moieties. In particular, there is an increasing request for multifunctional CLs having
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0191c0b3bb47afb97f7c5b3bbdfffba2
http://hdl.handle.net/2434/929924
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4
Synthesis and anti-bacterial activity of a library of 1,2-benzisothiazol-3(2H)-one (BIT) derivatives amenable of crosslinking to polysaccharides
Autor: Fiorenza Viani, Luca Merlini, Alessandra M. Martorana, Alessandra Polissi, Walter Panzeri, Yves M. Galante, Bianca Rossi
Publikováno v: Tetrahedron (Oxf., Print) 73 (2017): 1745–1761. doi:10.1016/j.tet.2017.02.025
info:cnr-pdr/source/autori:Viani F.; Rossi B.; Panzeri W.; Merlini L.; Martorana A.M.; Polissi A.; Galante Y.M./titolo:Synthesis and anti-bacterial activity of a library of 1,2-benzisothiazol-3(2H)-one (BIT) derivatives amenable of crosslinking to polysaccharides/doi:10.1016%2Fj.tet.2017.02.025/rivista:Tetrahedron (Oxf., Print)/anno:2017/pagina_da:1745/pagina_a:1761/intervallo_pagine:1745–1761/volume:73
1,2-Benzisothiazol-3(2H)-one (BIT) is one of the most common chemical biocides in industrial products, with a heterocyclic structure and a wide range of antimicrobial activity. A library of BIT derivatives was synthesized and characterized, from whic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b33b9bfc63914aaf54393bc18ee6598
https://doi.org/10.1016/j.tet.2017.02.025
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5
Enzyme oxidation of plant galactomannans yielding biomaterials with novel properties and applications, including as delivery systems
Autor: Paola Campia, Fiorenza Viani, Tiziana Silvetti, Milena Brasca, Yves M. Galante, Bianca Rossi, Luca Merlini
Publikováno v: Applied microbiology and biotechnology 102 (2018): 4687–4702. doi:10.1007/s00253-018-9028-z
info:cnr-pdr/source/autori:Galante Y.M.; Merlini L.; Silvetti T.; Campia P.; Rossi B.; Viani F.; Brasca M./titolo:Enzyme oxidation of plant galactomannans yielding biomaterials with novel properties and applications, including as delivery systems/doi:10.1007%2Fs00253-018-9028-z/rivista:Applied microbiology and biotechnology/anno:2018/pagina_da:4687/pagina_a:4702/intervallo_pagine:4687–4702/volume:102
New biomaterials from renewable sources and the development of “functionalized biopolymers” are fields of growing industrial interest. Plant polysaccharides represent a valid alternative to traditional synthetic polymers, which are obtained from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfb9f2ad6fdb3e4b79dfb6047c1959e
https://pubmed.ncbi.nlm.nih.gov/29700569
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6
Chiroptical Phenomena in Reverse Micelles: The Case of (1R,2S)-Dodecyl (2-hydroxy-1-methyl-2-phenylethyl)dimethylammonium Bromide (DMEB)
Autor: Franca Castiglione, Daniele Mendola, Angela Ruggirello, Vincenzo Turco Liveri, Giovanna Longhi, Marco Passarello, Fiorenza Viani, Andrea Mele, Sergio Abbate
Publikováno v: Chirality. 26:532-538
(1R,2S)-Dodecyl(2-hydroxy-1-methyl-2-phenylethyl)dimethylammonium bromide (DMEB) aggregates dispersed in carbon tetrachloride have been investigated by Fourier transform infrared (FT-IR), vibrational circular dichroism (VCD) and 1H nuclear magnetic r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c17e36ccaa8be610770e0cab86166e60
https://doi.org/10.1002/chir.22309
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7
Base catalyzed racemization of amino acid derivatives
Autor: Lorenzo Cerioli, Dario Arosio, Fiorenza Viani, Paola D'Arrigo, Stefano Servi, Davide Moscatelli, Davide Tessaro
Publikováno v: Tetrahedron: asymmetry
22 (2011): 851–856. doi:10.1016/j.tetasy.2011.05.005
info:cnr-pdr/source/autori:D'Arrigo, Paola; Arosio, Dario; Cerioli, Lorenzo; Moscatelli, Davide; Servi, Stefano; Viani, Fiorenza; Tessaro, Davide/titolo:Base catalyzed racemization of amino acid derivatives/doi:10.1016%2Fj.tetasy.2011.05.005/rivista:Tetrahedron: asymmetry (Print)/anno:2011/pagina_da:851/pagina_a:856/intervallo_pagine:851–856/volume:22
Amino acid thioesters used as substrates for a chemo-enzymatic dynamic kinetic resolution (DKR) must be designed with a high enough acidity to be rapidly racemized in the presence of a suitable base. Kinetic data obtained from experimental proton exc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d25153e85fa2a1dd37bbc3e472e26b
https://doi.org/10.1016/j.tetasy.2011.05.005
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8
Dimerizable Redox-Sensitive Triazine-Based Cationic Lipids for in vitro Gene Delivery
Autor: Marco Folini, Chiara Verpelli, Carlo Sala, Gabriele Candiani, Walter Panzeri, Fiorenza Viani, Massimo Frigerio, Matteo Zanda, Monica Sani, Luca Chiamenti, Nadia Zaffaroni
Publikováno v: ChemMedChem
2 (2007): 292–296. doi:10.1002/jgm.1186
info:cnr-pdr/source/autori:Candiani G., Frigerio M., Viani F., Verpelli C., Sala C., Chiamenti L., Zaffaroni N., Folini M., Sani M., Panzeri W., Zanda M./titolo:Dimerizable redox-sensitive triazine-based cationic lipids for in vitro gene delivery/doi:10.1002%2Fjgm.1186/rivista:ChemMedChem (Print)/anno:2007/pagina_da:292/pagina_a:296/intervallo_pagine:292–296/volume:2
Background: Despite the use of currently optimized lipofection conditions, including transfection in serum-depleted media, the efficiency of gene transfer is low and high transfection rates often induce cytotoxicity. A lipid formulation with transfec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fabcf3359687cd0ba44790cfdac244
https://doi.org/10.1002/cmdc.200600267
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9
Replacement of Isobutyl by Trifluoromethyl in Pepstatin A Selectively Affects Inhibition of Aspartic Proteinases
Autor: Massimo Frigerio, Matteo Zanda, Cristina Pesenti, Fiorenza Viani, Solange Meyer, Lars Prade, Andrew Jones, Christoph Binkert
Publikováno v: ChemBioChem
7 (2006): 181–186. doi:10.1002/cbic.200500180
info:cnr-pdr/source/autori:Binkert C., Frigerio M., Jones A., Meyer S., Pesenti C., Prade L., Viani F., Zanda M./titolo:Replacement of isobutyl by trifluoromethyl in pepstatin A selectively affects inhibition of aspartic proteinases/doi:10.1002%2Fcbic.200500180/rivista:ChemBioChem (Print)/anno:2006/pagina_da:181/pagina_a:186/intervallo_pagine:181–186/volume:7
Two bis-trifluoromethyl pepstatin A analogues, carboxylic acid 1 and its methyl ester 2, have been synthesised in order to probe the properties and size of the trifluoromethyl (Tfm) group and compare it to the "bigger" isobutyl that is present in pep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0b9a46fbcc71a9210ce830cea79943
https://doi.org/10.1002/cbic.200500180
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10
Stereocontrolled synthesis of hydroxyethylamine isosteres via chiral sulfoxide chemistry
Autor: Walter Panzeri, Alberto Arnone, Fiorenza Viani, Paolo Arosio, Cristina Pesenti, Matteo Zanda, Massimo Frigerio, Stefano Valdo Meille
Publikováno v: Tetrahedron letters 45 (2004): 5125–5129. doi:10.1016/j.tetlet.2004.04.160
info:cnr-pdr/source/autori:Pesenti C., Arnone A., Arosio P., Frigerio M., Meille S.V., Panzeri W., Viani F., Zanda M./titolo:Stereocontrolled synthesis of hydroxyethylamine isosteres via chiral sulfoxide chemistry/doi:10.1016%2Fj.tetlet.2004.04.160/rivista:Tetrahedron letters/anno:2004/pagina_da:5125/pagina_a:5129/intervallo_pagine:5125–5129/volume:45
A novel synthesis of enantiopure hydroxyethylamine isosteres 1 has been developed. Reaction of lithiated β-sulfinylethylamines 3 with N-Cbz-imines generated in situ from α-amino-sulfones 4 afforded in good to excellent yields and moderate stereocon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298aa56a089bfb4797a598e380dc78da
https://doi.org/10.1016/j.tetlet.2004.04.160
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