Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Fiorella Tonello"'
Autor:
Alejandro Montoya-Gómez, Fiorella Tonello, Barbara Spolaore, Maria Lina Massimino, Leonel Montealegre-Sánchez, Andrés Castillo, Nelson Rivera Franco, María José Sevilla-Sánchez, Luis Manuel Solano-Redondo, Mildrey Mosquera-Escudero, Eliécer Jiménez-Charris
Publikováno v:
Cells, Vol 12, Iss 23, p 2715 (2023)
Despite advances in chemotherapeutic drugs used against cervical cancer, available chemotherapy treatments adversely affect the patient’s quality of life. For this reason, new molecules from natural sources with antitumor potential and few side eff
Externí odkaz:
https://doaj.org/article/f4cfc9c7ead043b1ad5aea96659ec82a
Autor:
Fiorella Tonello
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1579 (2023)
Secreted phospholipases of type A2 (sPLA2s) are proteins of 14–16 kDa present in mammals in different forms and at different body sites. They are involved in lipid transformation processes, and consequently in various immune, inflammatory, and meta
Externí odkaz:
https://doaj.org/article/e188eeb2e1b04aff8f2b5bd651b4a701
Autor:
Caterina Peggion, Maria Lina Massimino, Roberto Stella, Raissa Bortolotto, Jessica Agostini, Arianna Maldi, Geppo Sartori, Fiorella Tonello, Alessandro Bertoli, Raffaele Lopreiato
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
TDP-43 is a nuclear protein involved in pivotal processes, extensively studied for its implication in neurodegenerative disorders. TDP-43 cytosolic inclusions are a common neuropathologic hallmark in amyotrophic lateral sclerosis (ALS) and related di
Externí odkaz:
https://doaj.org/article/7141b76667ba49b8bcdd2988f374db35
Autor:
Caterina Peggion, Fiorella Tonello
Publikováno v:
Toxins, Vol 13, Iss 4, p 290 (2021)
Snake venom phospholipases A2 (PLA2s) have sequences and structures very similar to those of mammalian group I and II secretory PLA2s, but they possess many toxic properties, ranging from the inhibition of coagulation to the blockage of nerve transmi
Externí odkaz:
https://doaj.org/article/43e37319ce8d46ec8c21df0dc9ae248f
Autor:
Vijay B. Arumugham, Cristina Ulivieri, Anna Onnis, Francesca Finetti, Fiorella Tonello, Daniel Ladant, Cosima T. Baldari
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
A central feature of the immune synapse (IS) is the tight compartmentalization of membrane receptors and signaling mediators that is functional for its ability to coordinate T cell activation. Second messengers centrally implicated in this process, s
Externí odkaz:
https://doaj.org/article/f606708f7f314857870d4f4f52a2b9b3
Autor:
Irene Zornetta, Fiorella Tonello
Publikováno v:
Toxins, Vol 4, Iss 7, Pp 536-553 (2012)
The mechanism of phagosome escape by intracellular pathogens is an important step in the infectious cycle. During the establishment of anthrax, Bacillus anthracis undergoes a transient intracellular phase in which spores are engulfed by local phagocy
Externí odkaz:
https://doaj.org/article/17a37eec8edf4d72b8641646a5a9a89b
Publikováno v:
Toxicon. 170:99-107
Almost all animal venoms contain secretory phospholipases A2 (PLA2s), 14 kDa disulfide-rich enzymes that hydrolyze membrane phospholipids at the sn-2 position, releasing lysophospholipids and fatty acids. These proteins, depending on their sequence,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c18e6ff6c160d8cc6df149778c91a2
https://doi.org/10.1016/j.toxicon.2019.09.019
https://doi.org/10.1016/j.toxicon.2019.09.019
Autor:
Fiorella Tonello, Caterina Peggion
Publikováno v:
Toxins
Volume 13
Issue 4
Toxins, Vol 13, Iss 290, p 290 (2021)
Volume 13
Issue 4
Toxins, Vol 13, Iss 290, p 290 (2021)
Snake venom phospholipases A2 (PLA2s) have sequences and structures very similar to those of mammalian group I and II secretory PLA2s, but they possess many toxic properties, ranging from the inhibition of coagulation to the blockage of nerve transmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c9ca90f83e8334b6d2206c7da01589
http://europepmc.org/articles/PMC8073766
http://europepmc.org/articles/PMC8073766
Autor:
Joby Robleto, Julián Fernández, Laura Monturiol-Gross, Stephanie Chaves-Araya, Sofía Vargas-Valerio, Fiorella Tonello, Bruno Lomonte
Publikováno v:
Toxicon, vol.197, pp.48-54
Kérwá
Universidad de Costa Rica
instacron:UCR
Kérwá
Universidad de Costa Rica
instacron:UCR
Phospholipases A2 (PLA2s) and PLA2-like proteins are significant components of snake venoms. Some of these proteins act as potent toxins causing muscle necrosis, which may lead to amputation in severe envenomings. Fundamental aspects of the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2707037077f7c08138625f794eb9e316
https://pubmed.ncbi.nlm.nih.gov/33862027
https://pubmed.ncbi.nlm.nih.gov/33862027
Autor:
Fiorella Tonello, Caterina Peggion
Publikováno v:
Proceedings of 1st International Electronic Conference on Toxins.
Phospholipases A2 (PLA2s) are important constituents of snake venom that, depending on their amino acid composition, possess several toxic properties whose main ones are neurotoxicity, myotoxicity, cardiotoxicity and impairing of haemostasis. They ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddffa6da8d52ba78aa31b05a3451856f
https://doi.org/10.3390/iect2021-09137
https://doi.org/10.3390/iect2021-09137