Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Fiorella C, Grandi"'
Autor:
Adam J. Carlton, Jing-Yi Jeng, Fiorella C. Grandi, Francesca De Faveri, Ana E. Amariutei, Lara De Tomasi, Andrew O’Connor, Stuart L. Johnson, David N. Furness, Steve D.M. Brown, Federico Ceriani, Michael R. Bowl, Mirna Mustapha, Walter Marcotti
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114025- (2024)
Summary: Type I spiral ganglion neurons (SGNs) convey sound information to the central auditory pathway by forming synapses with inner hair cells (IHCs) in the mammalian cochlea. The molecular mechanisms regulating the formation of the post-synaptic
Externí odkaz:
https://doaj.org/article/003f391f46fe499b876a09eda87c4a9d
Autor:
Eloise Berson, Anjali Sreenivas, Thanaphong Phongpreecha, Amalia Perna, Fiorella C. Grandi, Lei Xue, Neal G. Ravindra, Neelufar Payrovnaziri, Samson Mataraso, Yeasul Kim, Camilo Espinosa, Alan L. Chang, Martin Becker, Kathleen S. Montine, Edward J. Fox, Howard Y. Chang, M. Ryan Corces, Nima Aghaeepour, Thomas J. Montine
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Assay for Transposase Accessible Chromatin by sequencing (ATAC-seq) accurately depicts the chromatin regulatory state and altered mechanisms guiding gene expression in disease. However, bulk sequencing entangles information from different ce
Externí odkaz:
https://doaj.org/article/05827f0fc6bd405d8f51032b99aead11
Autor:
Mamta Singla, Michela Bruschi, Nidhi Bhutani, Pranay Agarwal, Constance R. Chu, Fiorella C. Grandi, Neety Sahu
Publikováno v:
Tissue Eng Part A
Mesenchymal stromal cells (MSCs) have been widely investigated for their regenerative capacity, anti-inflammatory properties and beneficial immunomodulatory effects across multiple clinical indications. Nevertheless, their widespread clinical utiliza
Autor:
Adam J Carlton, Jing‐Yi Jeng, Fiorella C Grandi, Francesca De Faveri, Federico Ceriani, Lara De Tomasi, Anna Underhill, Stuart L Johnson, Kevin P Legan, Corné J Kros, Guy P Richardson, Mirna Mustapha, Walter Marcotti
Publikováno v:
The EMBO Journal. 42
Autor:
Adam J, Carlton, Jing-Yi, Jeng, Fiorella C, Grandi, Francesca, De Faveri, Federico, Ceriani, Lara, De Tomasi, Anna, Underhill, Stuart L, Johnson, Kevin P, Legan, Corné J, Kros, Guy P, Richardson, Mirna, Mustapha, Walter, Marcotti
Publikováno v:
The EMBO journalReferences.
Sensory-independent Ca
Autor:
Hong-pyo Lee, Piera Smeriglio, Ovijit Chaudhuri, Nidhi Bhutani, Stuart B. Goodman, Pranay Agarwal, Fiorella C. Grandi
Publikováno v:
Nat Biomed Eng
Changes in the composition and viscoelasticity of the extracellular matrix in load-bearing cartilage influence the proliferation and phenotypes of chondrocytes, and are associated with osteoarthritis. However, the underlying molecular mechanism is un
Autor:
Nidhi Bhutani, Fiorella C. Grandi
Publikováno v:
Trends in Pharmacological Sciences. 41:557-569
Osteoarthritis (OA) is an age-associated disease characterized by chronic joint pain resulting from degradation of articular cartilage, inflammation of the synovial lining, and changes to the subchondral bone. Despite the wide prevalence, no FDA-appr
Autor:
Stephanie S. Holden, Frances S. Cho, Ted A. Yednock, Oumaima Aboubakr, Eleonora Aronica, Yaisa Andrews-Zwilling, Fiorella C. Grandi, Andrea J. Tenner, M. Ryan Corces, Bryan Higashikubo, Allison R. Morningstar, Sethu Sankaranarayanan, Logan J. Kuhn, Jeanne T. Paz, Poojan Suri, Anita Lüthi, Andrew H Chang, Alejandro Osorio Forero, Vidhu Mathur
Publikováno v:
Science
Science, 373(6560):eabj2685. American Association for the Advancement of Science
Science (New York, N.Y.), vol 373, iss 6560
Science, 373(6560):eabj2685. American Association for the Advancement of Science
Science (New York, N.Y.), vol 373, iss 6560
Neuroinflammation after brain injury Traumatic brain injury affects millions of people every year and is a major cause of disability worldwide. Most of the maladaptive outcomes develop months or years later and are thought to be caused by secondary i
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Autor:
Eleonora Migliore, Nithya Lingampalli, Nidhi Bhutani, Vittorio Sebastiano, Christian T. O’Donnell, Constance R. Chu, Fiorella C. Grandi, Cecilia Cisar, Pier Francesco Indelli, William H. Robinson, Jayme C.B. Koltsov
Publikováno v:
J Orthop Res
There is intense clinical interest in the potential effects of platelet-rich plasma (PRP) for the treatment of osteoarthritis (OA). This study tested the hypotheses that (i) "lower" levels of the inflammatory mediators (IMs), interleukin-1β, and tum