Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Fiora Bartoli"'
Autor:
Anna Rosati, Luigi Candussio, Enrico Crivellato, Fiora Bartoli Klugmann, Tullio Giraldi, Daniela Damiani, Angela Michelutti, Giuliana Decorti
Publikováno v:
Cellular Oncology, Vol 26, Iss 1-2, Pp 3-11 (2004)
Most of the substances used as fluorescent probes to study drug transport and the effect of efflux blockers in multidrug resistant cells have many drawbacks, such as toxicity, unspecific background, accumulation in mitochondria. New fluorescent compo
Externí odkaz:
https://doaj.org/article/22a30bd2a6b94f5ea182187828422a76
Publikováno v:
British Journal of Clinical Pharmacology. 73:651-655
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: In vitro lymphocyte steroid sensitivity has been suggested as a useful tool to predict in vivo response to glucocorticoid treatment in different inflammatory chronic diseases. A correlation between genetic po
Autor:
Gabriele Stocco, Paolo Tamaro, Federico Verzegnassi, Giuliana Decorti, Fiora Bartoli, Sara Marino, Marco Rabusin
Publikováno v:
Pediatric Blood & Cancer. 53:984-991
Background Glucocorticoids (GCs) play a fundamental role in the treatment of pediatric acute lymphoblastic leukemia (ALL), but therapy with these agents often results in a number of severe side effects. The aim of our study was to evaluate the associ
Publikováno v:
Toxicology Mechanisms and Methods. 18:763-769
The transport of doxorubicin and rhodamine 123, substrates of ABC transporters, was evaluated in the BeWo stabilized trophoblast cell line. Both compounds were taken up by BeWo cells, but their intracellular concentrations were highly dependent on te
Autor:
Annalisa Gotti, Gabriele Stocco, Arrigo Barabino, Stefano Martelossi, Alessandro Ventura, Fiora Bartoli, Giuliana Decorti, Marcella Montico
Publikováno v:
Inflammatory Bowel Diseases. 13:57-64
Background: Adverse drug reactions to azathioprine, the prodrug of 6-mercaptopurine, occur in 15%–38% of patients and the majority are not explained by thiopurine-S-methyltransferase (TPMT) deficiency. Azathioprine is known to induce glutathione de
Autor:
Giuseppe Toffoli, Stefano Martelossi, Giuliana Decorti, Gabriele Stocco, Massimo Fontana, Tullio Giraldi, Paolo Lionetti, Fiora Bartoli, Franca Sartor, Alessandro Ventura, Arrigo Barabino
Publikováno v:
Digestive Diseases and Sciences. 51:474-479
Inflammatory bowel disease (IBD) has been related to mutations of methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in the metabolism of folate and methionine, both of which are important factors in DNA methylation and synthesis. A mutat
Autor:
Angela Michelutti, Fiora Bartoli Klugmann, Giuliana Decorti, Tullio Giraldi, Enrico Crivellato, Daniela Damiani, Luigi Candussio, A.M. Rosati
Publikováno v:
Cellular Oncology : the Official Journal of the International Society for Cellular Oncology
Scopus-Elsevier
Cellular Oncology, Vol 26, Iss 1-2, Pp 3-11 (2004)
Scopus-Elsevier
Cellular Oncology, Vol 26, Iss 1-2, Pp 3-11 (2004)
Most of the substances used as fluorescent probes to study drug transport and the effect of efflux blockers in multidrug resistant cells have many drawbacks, such as toxicity, unspecific background, accumulation in mitochondria. New fluorescent compo
Autor:
A.M. Rosati, Enrico Crivellato, Luigi Candussio, Franco Mallardi, Fiora Bartoli-Klugmann, Giuliana Decorti
Publikováno v:
Journal of Histochemistry & Cytochemistry. 50:731-734
Several fluorescent probes have been used in functional studies to analyze drug transport in multidrug-resistant cells by fluorescent microscopy. Because many of these molecules have some drawbacks, such as toxicity, nonspecific background, or accumu
Autor:
Giuliana Decorti, A.M. Rosati, Luigi Candussio, Tullio Giraldi, Fiora Bartoli Klugmann, Enrico Crivellato, Marilena Granzotto
Publikováno v:
The Histochemical Journal. 33:259-266
To clarify the function of the multidrug transporter P-glycoprotein in mast cells we used the green fluorescent compound Bodipy-FL-verapamil, which is a substrate of P-glycoprotein. This compound is also transported by Multidrug Resistance-related Pr
Autor:
Franco Mallardi, Luigi Candussio, Fiora Bartoli Klugmann, Giuliana Decorti, A.M. Rosati, Enrico Crivellato
Publikováno v:
Histochemical Journal. 31:635-643
The subcellular distribution of doxorubicin was evaluated in living non-fixed LLC-PK1 cells, which maintain the structural and functional characteristics of the kidney proximal tubule epithelium and also express P-glycoprotein. After 10 min incubatio