Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Fionnuala B. Hickey"'
Autor:
Eóin C. O'Brien, Carla A. White, Jason Wyse, Emma Leacy, Richard K. Porter, Mark A. Little, Fionnuala B. Hickey
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Clinical and experimental data suggest that pathogenesis in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is driven by ANCA-mediated activation of neutrophils and monocytes. While the role of neutrophils has been extensively inves
Externí odkaz:
https://doaj.org/article/3f349d7f5626495b80d6cc89bae479b3
Autor:
James S. O’Donnell, T. Martin Feeley, D. Rónán Collins, Sean O’Neill, Stephen J.X. Murphy, Deirdre R. Smith, Joseph Harbison, Sinéad M. Murphy, Sean Tierney, Tara Coughlan, Mary-Paula Colgan, Justin A. Kinsella, Fionnuala B. Hickey, George Hamilton, Jamie M. O’Sullivan, Dominick J. H. McCabe, Soon Tjin Lim, Bridget Egan, Desmond O'Neill, Prakash Madhavan
Publikováno v:
Thromb Haemost
Background The relationship between von Willebrand factor antigen (VWF:Ag), VWF propeptide (VWFpp), VWFpp/VWF:Ag ratio, ADAMTS13 activity, and microembolic signal (MES) status in carotid stenosis is unknown. Methods This prospective, multicenter stud
Autor:
Mark A. Little, Richard K. Porter, Fionnuala B. Hickey, Carla A White, Eóin C O'Brien, Emma Leacy, Jason Wyse
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Clinical and experimental data suggest that pathogenesis in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is driven by ANCA-mediated activation of neutrophils and monocytes. While the role of neutrophils has been extensively inves
Autor:
Susan Murray, Sarah M Moran, Derek G. Doherty, Eóin C O'Brien, Alan Kennedy, Ana Moreno-Olivera, Mark A. Little, Barbara Fazekas, Dearbhaile Dooley, Jennifer Scott, Niall Conlon, Yvelynne Kelly, Ashanty M. Melo, Paul V. O’Hara, Fionnuala B. Hickey
Publikováno v:
Clinical and Experimental Immunology. 191:180-188
Summary Innate lymphocyte populations, such as innate lymphoid cells (ILCs), γδ T cells, invariant natural killer T (iNK T) cells and mucosal-associated invariant T (MAIT) cells are emerging as important effectors of innate immunity and are involve
Publikováno v:
Rheumatology. 58
Autor:
Joana Cabral, Barry Moran, Vincent P. O’Reilly, Alice M Coughlan, Aisling Morrin, Mark A. Little, Aisling Ui Mhaonaigh, Amrita Dwivedi, Fionnuala B. Hickey
Publikováno v:
Rheumatology. 58
Autor:
Fionnuala B. Hickey, Mark A. Little, Michelle Ryan, Pamela Kelly, Vincent P. O’Reilly, Cliona O'Farrelly, Alice M Coughlan, Paul Crotty, Sarah Whelan, Cathal Harmon, Eóin C O'Brien
Publikováno v:
Stem Cells and Development. 25:530-541
Poor myeloid engraftment remains a barrier to experimental use of humanized mice. Focusing primarily on peripheral blood cells, we compared the engraftment profile of NOD-scid-IL2Rγc(-/-) (NSG) mice with that of NSG mice transgenic for human membran
Autor:
Vincent P. O’Reilly, Cathal O'Brien, Stephen P. Finn, M. T. Lindemeyer, Mark A. Little, Fionnuala B. Hickey, Michelle Ryan, Clemens D. Cohen, L. A. Elliot, Peter Heeringa, Conleth Feighery, Michael R. Clarkson, J. Lau, Paul V. O’Hara, Shane O’Meachair, Eóin C O'Brien, Wayel H. Abdulahad, D. Sandoval, Sarah M Moran, Colm Buckley, E. Connolly, Gerjan J. Dekkema, George Mellotte, J-S F. Sanders, A. J. Dorman, Patrick T. Murray, Limy Wong, Claire Kennedy, Alice M Coughlan
Publikováno v:
Journal of the American Society of Nephrology : JASN. 29(8)
A specific biomarker that can separate active renal vasculitis from other causes of renal dysfunction is lacking, with a kidney biopsy often being required. Soluble CD163 (sCD163), shed by monocytes and macrophages, has been reported as a potential b
Autor:
Fionnuala B. Hickey, Finian Martin
Publikováno v:
Current Diabetes Reports. 18
The purpose of this review is to examine the proposed role of immune modulation in the development and progression of diabetic kidney disease (DKD). Diabetic kidney disease has not historically been considered an immune-mediated disease; however, inc
Autor:
Thomas Mehrling, Gareth Brady, Eóin C O'Brien, Peter Heeringa, Fionnuala B. Hickey, Mark A. Little, Barbara Fazekas, Mirjan M. van Timmeren, Dearbhaile Dooley, Emma Leacy, Charles D. Pusey, Vincent P. O’Reilly, Frederick W.K. Tam
Publikováno v:
Kidney International, 94(5), 926-936. ELSEVIER SCIENCE INC
Current therapies for treating antineutrophil cytoplasm autoantibody (ANCA)-associated vasculitis include cyclophosphamide and corticosteroids. Unfortunately, these agents are associated with severe adverse effects, despite inducing remission in most