Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fiona Y. Glassman"'
Autor:
Nhan H. Nguyen, Fiona Y. Glassman, Robert K. Dingman, Gautam N. Shenoy, Elizabeth A. Wohlfert, Jason G. Kay, Richard B. Bankert, Sathy V. Balu-Iyer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The safety and efficacy of several life-saving therapeutic proteins are compromised due to their immunogenicity. Once a sustained immune response against a protein-based therapy is established, clinical options that are safe and cost-effecti
Externí odkaz:
https://doaj.org/article/1786baa1e47743e4a012fbcf4ceadcfd
Publikováno v:
Immunol Invest
Phosphatidylserine (PS) is a naturally occurring anionic phospholipid that is primarily located in the inner leaflet of eukaryotic cell membranes. The role of PS during apoptosis is one of the most studied biological functions of PS. Externalization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87be02940855ec91a410003650453e18
https://doi.org/10.1080/08820139.2020.1738456
https://doi.org/10.1080/08820139.2020.1738456
Autor:
Elizabeth A. Wohlfert, Nhan H. Nguyen, Fiona Y. Glassman, Gautam N Shenoy, Sathy V. Balu-Iyer, Robert K. Dingman, Richard B. Bankert, Jason G. Kay
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
The safety and efficacy of several life-saving therapeutic proteins are compromised due to their immunogenicity. Once a sustained immune response against a protein-based therapy is established, clinical options that are safe and cost-effective become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a401eb8a90634c902be93441a8fa3683
https://doi.org/10.1038/s41598-021-97333-0
https://doi.org/10.1038/s41598-021-97333-0
Autor:
Sathy V. Balu-Iyer, Fiona Y. Glassman
Publikováno v:
International Journal of Pharmaceutics. 548:642-648
A major complication with enzyme replacement therapy of Factor VIII (FVIII) in Hemophilia A (HA) is the development of anti-drug antibodies. Recently, we have shown that FVIII administration in the presence of heterogeneous phosphatidylserine (PS) na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aba41e8690ce789d0aa096dd4524af5
https://doi.org/10.1016/j.ijpharm.2018.07.018
https://doi.org/10.1016/j.ijpharm.2018.07.018
Autor:
Radha Ramakrishnan, Jennifer L. Schneider, Robert K. Dingman, Murali Ramanathan, Fiona Y. Glassman, Sathy V. Balu-Iyer, Richard B. Bankert
Publikováno v:
Journal of Pharmaceutical Sciences. 107:2048-2054
Phosphatidylserine (PS) exposure during apoptosis leads to silent clearance of cells without adverse immune reactions to self-proteins. Given the biological functions of PS in cellular cleanup and global immunosuppression, we hypothesized that admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3177f34fce51fe7555a6d66eaa3ef39e
https://doi.org/10.1016/j.xphs.2018.03.027
https://doi.org/10.1016/j.xphs.2018.03.027