Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Fiona V Cresswell"'
Autor:
David B Meya, Alison Elliott, David R Boulware, Fiona V Cresswell, Carson M Quinn, Mable Kabahubya, Ananta S Bangdiwala, Sarah Lofgren, John Kasibante, Alice Namudde, Noeline Nakasujja
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Background: The toll of tuberculous meningitis (TBM) in both mortality and disability is considerable, but advancements in rehabilitation have the potential to improve the functional abilities and the quality of survivors’ lives. However, the typic
Externí odkaz:
https://doaj.org/article/3db25ef226384aa69b56f383b04dd308
Autor:
Nathan C Bahr, Fiona V Cresswell, Nguyen Thuy Thuong Thuong, Rachel P.J. Lai, Angharad G. Davis, David R Boulware, Robert J Wilkinson, Johan Schoeman, Marise Bremer, Joseph Donovan, Ronald Van Toorn, Guy E Thwaites, Ariba Dadabhoy
Publikováno v:
Wellcome Open Research, Vol 5 (2021)
A dysregulated host immune response significantly contributes to morbidity and mortality in tuberculous meningitis (TBM). Effective host directed therapies (HDTs) are critical to improve survival and clinical outcomes. Currently only one HDT, dexamet
Externí odkaz:
https://doaj.org/article/1082f9028b78463baff862754b13c9a1
Autor:
Peter J Dodd, Muhammad Osman, Fiona V Cresswell, Anna M Stadelman, Nguyen Huu Lan, Nguyen Thuy Thuong Thuong, Morris Muzyamba, Lisa Glaser, Sicelo S Dlamini, James A Seddon
Publikováno v:
PLOS Global Public Health, Vol 1, Iss 12, p e0000069 (2021)
Tuberculous meningitis (TBM) is the most lethal form of tuberculosis. The incidence and mortality of TBM is unknown due to diagnostic challenges and limited disaggregated reporting of treated TBM by existing surveillance systems. We aimed to estimate
Externí odkaz:
https://doaj.org/article/5e2ac906120a4251bf9ed8535523dcee
Autor:
Fiona V Cresswell, Angharad G. Davis, Kusum Sharma, Robindra Basu Roy, Ahmad Rizal Ganiem, Enock Kagimu, Regan Solomons, Robert J. Wilkinson, Nathan C Bahr, Nguyen Thuy Thuong Thuong, Tuberculous Meningitis International Research Consortium
Publikováno v:
Wellcome Open Research, Vol 4 (2021)
The pathogenesis of Tuberculous meningitis (TBM) is poorly understood, but contemporary molecular biology technologies have allowed for recent improvements in our understanding of TBM. For instance, neutrophils appear to play a significant role in th
Externí odkaz:
https://doaj.org/article/04e368a4097b43cda1a7ffab7f4734cf
Autor:
Suzaan Marais, Fiona V Cresswell, Raph L. Hamers, Lindsey H.M. te Brake, Ahmad R. Ganiem, Darma Imran, Ananta Bangdiwala, Emily Martyn, John Kasibante, Enock Kagimu, Abdu Musubire, Kartika Maharani, Riwanti Estiasari, Ardiana Kusumaningrum, Nadytia Kusumadjayanti, Vycke Yunivita, Kogieleum Naidoo, Richard Lessells, Yunus Moosa, Elin M. Svensson, Katherine Huppler Hullsiek, Rob E. Aarnoutse, David R. Boulware, Reinout van Crevel, Rovina Ruslami, David B. Meya
Publikováno v:
Wellcome Open Research, Vol 4 (2020)
Background: Tuberculous meningitis (TBM), the most severe form of tuberculosis (TB), results in death or neurological disability in >50%, despite World Health Organisation recommended therapy. Current TBM regimen dosages are based on data from pulmon
Externí odkaz:
https://doaj.org/article/d06cf107e8164549a460f56a6aa07fa4
Autor:
Fiona V Cresswell, Angharad G. Davis, Kusum Sharma, Robindra Basu Roy, Ahmad Rizal Ganiem, Enock Kagimu, Regan Solomons, Robert J. Wilkinson, Nathan C Bahr, Nguyen Thuy Thuong Thuong, Tuberculous Meningitis International Research Consortium
Publikováno v:
Wellcome Open Research, Vol 4 (2020)
The pathogenesis of Tuberculous meningitis (TBM) is poorly understood, but contemporary molecular biology technologies have allowed for recent improvements in our understanding of TBM. For instance, neutrophils appear to play a significant role in th
Externí odkaz:
https://doaj.org/article/de26b023cf4b487f8abf8714ffd9863b
Autor:
Ursula K Rohlwink, Felicia C Chow, Sean Wasserman, Sofiati Dian, Rachel PJ Lai, Lidya Chaidir, Raph L Hamers, Robert J Wilkinson, David R Boulware, Fiona V Cresswell, Arjan van Laarhoven, Tuberculous Meningitis International Research Consortium
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Tuberculous meningitis (TBM), the most severe manifestation of tuberculosis, has poorly understood immunopathology and high mortality and morbidity despite antituberculous therapy. This calls for accelerated clinical and basic science research in thi
Externí odkaz:
https://doaj.org/article/8f8ef9921dce440e87c81b8c9c0901f3
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Cryptococcal meningitis is a leading cause of morbidity and mortality among HIV-infected persons, accounting for 15% of AIDS-related deaths. Visual disturbance is commonly reported, and a wide range of ophthalmic signs may be present on examination.
Externí odkaz:
https://doaj.org/article/558d90a509764e848cf8642929d88e3b
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Cryptococcal meningitis is a leading cause of morbidity and mortality among HIV-infected persons, accounting for 15% of AIDS-related deaths. Visual disturbance is commonly reported, and a wide range of ophthalmic signs may be present on examination.
Externí odkaz:
https://doaj.org/article/a4df2b9d74024f93b5846e2332dffb0f
Autor:
Caleb P. Skipper, Katherine Huppler Hullsiek, Fiona V. Cresswell, Kiiza K. Tadeo, Michael Okirwoth, Mark Blackstad, Nelmary Hernandez-Alvarado, Claudia Fernández-Alarcón, Stewart Walukaga, Emily Martyn, Jayne Ellis, Kenneth Ssebambulidde, Lillian Tugume, Edwin Nuwagira, Joshua Rhein, David B. Meya, David R. Boulware, Mark R. Schleiss
Publikováno v:
International Journal of Infectious Diseases. 122:785-792
CMV viremia is associated with increased mortality in persons with HIV. We previously demonstrated that CMV viremia was a risk factor for 10-week mortality in antiretroviral therapy (ART)-naïve persons with cryptococcal meningitis. We investigated w