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Akademický článek

EphA3 CAR T cells are effective against glioblastoma in preclinical models

Autor: Xiang Li, Lea Lekieffre, Corey Smith, Rajiv Khanna, Fiona Smith, Paulo Martins, Bryan W Day, Rochelle C J D’Souza, Niclas Skarne, Shane Horsefield, Madusha Ranjankumar, Thuy T Le, Jacqueline Burrows

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)

Background Adoptive T-cell therapy targeting antigens expressed in glioblastoma has emerged as a potential therapeutic strategy to prevent or delay recurrence and prolong overall survival in this aggressive disease setting. Ephrin receptor A3 (EphA3)

Externí odkaz: https://doaj.org/article/f073a3e372844957a36b7c604f6bd066

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A novel mouse model for Sézary Syndrome using xenotransplantation of Sézary cells into immunodeficient RAG2−/−γc−/−mice

Autor: Jacoba J. Out-Luiting, Maarten H. Vermeer, Fiona Smit, Kim G. Vermeer, Leslie van der Fits, Kees Weijer, Lisanne van Zijl, Stephan M. Pouw, Cornelis P. Tensen, Heggert Rebel

Publikováno v: Experimental Dermatology, 21(9), 706-709
Experimental dermatology, 21(9), 706-709. Wiley-Blackwell

Isoprenylcysteine (IPC) molecules modulate G-protein-coupled receptor signalling. The archetype of this class is N-acetyl-S-farnesyl-l-cysteine (AFC). Topical application of AFC locally inhibits skin inflammation and elicitation of contact hypersensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32fe4af254200ee30812fe12b19ff0e
https://doi.org/10.1111/j.1600-0625.2012.01556.x

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Proximal Fluid Proteome Profiling of Mouse Colon Tumors Reveals Biomarkers for Early Diagnosis of Human Colorectal Cancer

Publikováno v: Fijneman, R J A, de Wit, M, Pourghiasian, M, Piersma, S R, Pham, T V, Warmoes, M O, Lavaei, M, Piso, C, Smit, F, Delis-van Diemen, P M, van Turenhout, S T, Terhaar sive Droste, J S, Mulder, C J J, Blankenstein, M A, Roobanus-Maandag, E C, Smits, R, Fodde, R, van Hinsbergh, V W M, Meijer, G A & Jimenez, C R 2012, ' Proximal Fluid Proteome Profiling of Mouse Colon Tumors Reveals Biomarkers for Early Diagnosis of Human Colorectal Cancer ', Clinical Cancer Research, vol. 18, no. 9, pp. 2613-2624 . https://doi.org/10.1158/1078-0432.CCR-11-1937
Clinical Cancer Research, 18(9), 2613-2624. American Association for Cancer Research Inc.

Purpose: Early detection of colorectal cancer (CRC) and its precursor lesions is an effective approach to reduce CRC mortality rates. This study aimed to identify novel protein biomarkers for the early diagnosis of CRC. Experimental Design: Proximal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acad41efd316107684b0a57fd873ebc
https://doi.org/10.1158/1078-0432.ccr-11-1937

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Akademický článek

Developing peatland ecosystem accounts to guide targets for restoration

Autor: Catherine Farrell, Lisa Coleman, Daniel Norton, Mary Kelly-Quinn, Carl Obst, Mark Eigenraam, Cathal O'Donoghue, Stephen Kinsella, Fiona Smith, Iseult Sheehy, Jane Stout

Publikováno v: One Ecosystem, Vol 6, Iss , Pp 1-24 (2021)

The United Nations System of Environmental and Economic Accounting - Ecosystem Accounting (SEEA EA) is a geospatial approach, whereby existing data on ecosystem stocks and flows are collated to show changes over time. The framework has been proposed

Externí odkaz: https://doaj.org/article/8642fc1953c9429b93aeceed2100a0d8

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