Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Fiona S. MacBeath"'
Autor:
Martyn Frederickson, Fiona S. MacBeath, Gareth M. Davies, Edwin Haslam, Richard Cross, Roger Brettle
Publikováno v:
Tetrahedron. 52:10547-10556
The use of (−)-shikimic acid as starting material in the syntheses of a series of C-3 halogenated derivatives including the analogous 3α- and 3β-fluoro and 3β-chloro acids is described together with the first stereospecific synthesis of (−)-3-
Autor:
Edwin Haslam, Gareth M. Davies, Fiona S. MacBeath, Richard Cross, Roger Brettle, Martyn Frederickson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1275-1278
(3 R )- and (3 S )-Fluoro-(4 R ,5 R )-dihydroxy-1-cyclohexene-1-carboxylic acids (the (3 R )- and (3 S )-fluoro analogues of (−)-shikimic acid) have been synthesised from (−)-shikimic acid via an intermediate epoxide (a fungal metabolite from Cha
Autor:
Martyn Frederickson, Gareth M. Davies, Fiona S. MacBeath, Edwin Haslam, Neil A. Bailey, Roger Brettle, Harry Adams, Richard Cross
Publikováno v:
Tetrahedron. 52:8565-8580
The first successful method for the introduction of nitrogenous functionality at C-3 of the shikimate nucleus has been developed and has allowed the synthesis of (−)-3(R)-amino-4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid [the 3(R)-amino ana
Autor:
Trevor John Grinter, Graham R. Geen, Martin J. Parratt, Bernadette M. Choudary, Fiona S. MacBeath
Publikováno v:
Nucleosides and Nucleotides. 13:979-996
Reaction of 2-amino-6-chloropurine with trans-2-alkyl-5-iodoethyl-1,3-dioxanes under basic conditions afforded N-9 and N-7 alkylated products, the product ratio obtained being dependent on the size of the 2-alkyl group. This allowed a highly regiosel
Autor:
Fiona S. MacBeath, Graham R. Geen, Martin J. Parratt, Bernadette M. Choudary, Trevor John Grinter
Publikováno v:
ChemInform. 26
Reaction of 2-amino-6-chloropurine with trans-2-alkyl-5-iodoethyl-1,3-dioxanes under basic conditions afforded N-9 and N-7 alkylated products, the product ratio obtained being dependent on the size of the 2-alkyl group. This allowed a highly regiosel
Autor:
Martyn Frederickson, Fiona S. MacBeath, Edwin Haslam, Gareth M. Davies, Richard Cross, Roger Brettle
Publikováno v:
ChemInform. 27
(3 R )- and (3 S )-Fluoro-(4 R ,5 R )-dihydroxy-1-cyclohexene-1-carboxylic acids (the (3 R )- and (3 S )-fluoro analogues of (−)-shikimic acid) have been synthesised from (−)-shikimic acid via an intermediate epoxide (a fungal metabolite from Cha
Autor:
Fiona S. MacBeath, Roger Brettle, Richard Cross, Gareth M. Davies, Edwin Haslam, Martyn Frederickson
Publikováno v:
ChemInform. 27
The use of (−)-shikimic acid as starting material in the syntheses of a series of C-3 halogenated derivatives including the analogous 3α- and 3β-fluoro and 3β-chloro acids is described together with the first stereospecific synthesis of (−)-3-
Autor:
Gareth M. Davies, Fiona S. MacBeath, Edwin Haslam, Neil A. Bailey, Richard Cross, Roger Brettle, Harry Adams, Martyn Frederickson
Publikováno v:
ChemInform. 27
The first successful method for the introduction of nitrogenous functionality at C-3 of the shikimate nucleus has been developed and has allowed the synthesis of (−)-3(R)-amino-4(R),5(R)-dihydroxy-1-cyclohexene-1-carboxylic acid [the 3(R)-amino ana