Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Fiona O'Neill"'
Autor:
Neil T Conlon, Sandra Roche, Amira F Mahdi, Alacoque Browne, Laura Breen, Johanna Gaubatz, Justine Meiller, Fiona O'Neill, Lorraine O'Driscoll, Mattia Cremona, Bryan T Hennessy, Lisa D Eli, John Crown, Denis M Collins
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102073- (2024)
Background: HER2-targeted therapies have revolutionised the treatment of HER2-positive breast cancer. However, de novo resistance or the emergence of acquired resistance is a persistent clinical problem. Here we report that neratinib, an irreversible
Externí odkaz:
https://doaj.org/article/80c2e8e9bf2e4172bafb263c57f5769f
Publikováno v:
Plasma, Vol 7, Iss 2, Pp 284-299 (2024)
A detailed review of the scientific literature was undertaken to examine the most recent developments in plasma processing in the field of medicine. The first part of the review includes a detailed breakdown of the different types of coatings that ca
Externí odkaz:
https://doaj.org/article/be2302cf1c604c5ea017bfa90be25621
Autor:
Beatrice Olayiwola, Fiona O’Neill, Chloe Frewen, Darren F. Kavanagh, Rosemary O’Hara, Liam O’Neill
Publikováno v:
Pathogens, Vol 13, Iss 4, p 326 (2024)
Hospital-acquired infections (HAIs) remain a significant factor in hospitals, with implant surfaces often becoming contaminated by highly resistant strains of bacteria. Recent studies have shown that electrical plasma discharges can reduce bacterial
Externí odkaz:
https://doaj.org/article/6d35c252a68f47b682a5682f788ce5a2
Autor:
Sandra Roche, Patricia Gaule, Deirdre Winrow, Nupur Mukherjee, Fiona O'Neill, Neil T Conlon, Justine Meiller, Denis M Collins, Alexandra Canonici, Mohammed Ibrahim Fawsi, Alejandra Estepa-Fernández, Stephen F Madden, John Crown, Norma O'Donovan, Alex J Eustace
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282512 (2023)
Triple Negative Breast Cancer (TNBC), a subtype of breast cancer, has fewer successful therapeutic therapies than other types of breast cancer. Insulin-like growth factor receptor 1 (IGF1R) and the Insulin receptor (IR) are associated with poor outco
Externí odkaz:
https://doaj.org/article/b9644b158fb94f80a2b68dadca1eef19
Autor:
Fiona O’Neill, Taylor-Jade Allen-Coyle, Sandra Roche, Justine Meiller, Neil T. Conlon, Niall Swan, Robert M. Straubinger, Justin Geoghegan, Ninfa L. Straubinger, Kevin Conlon, Ray McDermott, Finbarr O’Sullivan, Michael Henry, Paula Meleady, Gerard McVey, Robert O’Connor, Michael Moriarty, Martin Clynes
Publikováno v:
Life, Vol 13, Iss 3, p 608 (2023)
Herein, we describe the global comparison of miRNAs in human pancreatic cancer tumors, adjacent normal tissue, and matched patient-derived xenograft models using microarray screening. RNA was extracted from seven tumor, five adjacent normal, and eigh
Externí odkaz:
https://doaj.org/article/a7c66f94d63d447e9e0fc09d6ba50f6e
Autor:
Alexandra Canonici, Alacoque L. Browne, Mohamed F. K. Ibrahim, Kevin P. Fanning, Sandra Roche, Neil T. Conlon, Fiona O’Neill, Justine Meiller, Mattia Cremona, Clare Morgan, Bryan T. Hennessy, Alex J. Eustace, Flavio Solca, Norma O’Donovan, John Crown
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic options. Epidermal growth factor receptor (EGFR) has been shown to be over-expressed in TNBC and represents a rational treatment targe
Externí odkaz:
https://doaj.org/article/30ed8d6b4bc948429c56a9912d216c9d
Autor:
Orla Coleman, Michael Henry, Fiona O'Neill, Sandra Roche, Niall Swan, Lorraine Boyle, Jean Murphy, Justine Meiller, Neil T. Conlon, Justin Geoghegan, Kevin C. Conlon, Vincent Lynch, Ninfa L. Straubinger, Robert M. Straubinger, Gerard McVey, Michael Moriarty, Paula Meleady, Martin Clynes
Publikováno v:
Proteomes, Vol 6, Iss 4, p 45 (2018)
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide; it develops in a relatively symptom-free manner, leading to rapid disease progression and metastasis, leading to a 5-year survival rate of less than 5%. A lack of depe
Externí odkaz:
https://doaj.org/article/f10951bc0cb2430db525772b88936f29
Autor:
Sara Noorani, Shannon R. Nelson, Neil T. Conlon, Justine Meiller, Ekaterina Shcheglova, Alice Usai, Jojanneke Stoof, Letizia Palanga, Fiona O’Neill, Sandra Roche, Maura B. Cotter, Niall Swan, Naomi Walsh
Publikováno v:
Organoids; Volume 1; Issue 2; Pages: 168-183
Pancreatic cancer is a highly lethal disease. Therapeutic resistance to chemotherapy is a major cause of treatment failure and recurrence in pancreatic cancer. Organoids derived from cancer stem cells (CSC) are promising models for the advancement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb5642f7a2d7bd2126e62834b9b9b8e
Autor:
Fiona O'Neill, Jeanne-Marie Viljoen
Publikováno v:
Language and Intercultural Communication. 21:572-587
Intercultural pedagogies are increasingly seen as affording opportunities for students to share perspectives, understandings and knowledge. In the shift towards such pedagogies, ways that language is conceptualised and the interrelationship between l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bd3b3b3cc5da77c4029567a9c4d6a2
https://doi.org/10.1080/14708477.2021.1888965
https://doi.org/10.1080/14708477.2021.1888965
Autor:
Fiona O'Neill, Orla Coleman, Niall Swan, Michael Moriarty, Martin Clynes, Gerard McVey, Kevin C. Conlon, Michael Henry, Sandra Roche, Justin Geoghegan, Paula Meleady
Publikováno v:
Pancreas. 49:1109-1116
Objectives A limited repertoire of good pancreatic ductal adenocarcinoma (PDAC) models is one of the main barriers in developing effective new PDAC treatments. We aimed to characterize 6 commonly used PDAC cell lines and compare them with PDAC patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5cd2d81d1abbdff412126bdf0aec24
https://doi.org/10.1097/mpa.0000000000001633
https://doi.org/10.1097/mpa.0000000000001633