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The tumour suppressor p53 is activated following stress and initiates a heterogeneous response in a cell-, tissue- and stress-dependent manner. This heterogeneity is reflected in the different physiological outcomes that follow p53 activation. One me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c10bb5c5db50c9d97918c7232ee284a
https://doi.org/10.1038/nrm2451
https://doi.org/10.1038/nrm2451
Autor:
Dimitris P. Xirodimas, David P. Lane, Mark K. Saville, Fiona Murray-Zmijewski, Jean-Christophe Bourdon, Geng Liu, Kenneth Fernandes, Alexandra Diot
Publikováno v:
Genes & Development. 19:2122-2137
The recently discovered p53-related genes, p73 and p63, express multiple splice variants and N-terminally truncated forms initiated from an alternative promoter in intron 3. To date, no alternative promoter and multiple splice variants have been desc