Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fiona M. Rudkin"'
Autor:
María Fernanda Alonso, Judith M. Bain, Fiona M. Rudkin, Lars P. Erwig, Alistair J.P. Brown, Neil A.R. Gow
Publikováno v:
The Cell Surface, Vol 9, Iss , Pp 100106- (2023)
Externí odkaz:
https://doaj.org/article/30426ef88bc143d598db4acfd6573381
Autor:
María Fernanda Alonso, Judith M. Bain, Fiona M. Rudkin, Lars P. Erwig, Alistair J.P. Brown, Neil A.R. Gow
Publikováno v:
The Cell Surface, Vol 8, Iss , Pp 100082- (2022)
Phagocytosis is an essential component of our immune defence against fungal pathogens. Differences in the dynamics of phagocyte migration, recognition, uptake and phagolysosome maturation are dependent on the characteristics of the fungal cargo, and
Externí odkaz:
https://doaj.org/article/ccb6820628234afcb4260568f4e8cb07
Autor:
Fiona M. Rudkin, Ingrida Raziunaite, Hillary Workman, Sosthene Essono, Rodrigo Belmonte, Donna M. MacCallum, Elizabeth M. Johnson, Lisete M. Silva, Angelina S. Palma, Ten Feizi, Allan Jensen, Lars P. Erwig, Neil A. R. Gow
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Late diagnosis and ineffective treatment of fungal infections lead to high mortality. Here, Rudkin et al. generate anti-Candida human monoclonal antibodies with diagnostic and therapeutic potential, by expressing recombinant antibodies from genes clo
Externí odkaz:
https://doaj.org/article/3962deb6cda443548deab4a2e58b1fbe
Autor:
Fiona M. Rudkin, Judith M. Bain, Catriona Walls, Leanne E. Lewis, Neil A. R. Gow, Lars P. Erwig
Publikováno v:
mBio, Vol 4, Iss 6 (2013)
ABSTRACT An important first line of defense against Candida albicans infections is the killing of fungal cells by professional phagocytes of the innate immune system, such as polymorphonuclear cells (PMNs) and macrophages. In this study, we employed
Externí odkaz:
https://doaj.org/article/617564fc7d054d9bab8a1142f5a00331
Autor:
Ten Feizi, Lars P. Erwig, Sosthene Essono, Rodrigo Belmonte, Hillary Workman, Lisete M. Silva, Angelina S. Palma, Fiona M. Rudkin, Allan Jensen, Elizabeth M. Johnson, Ingrida Raziunaite, Donna M. MacCallum, Neil A. R. Gow
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Rudkin, F, Raziunaite, I, Workman, H, Essono, S, Belmonte, R, MacCallum, D M, Johnson, E M, Silva, L M, Palma, A S, Feizi, T, Jensen, A, Erwig, L P & Gow, N A R 2018, ' Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis ', Nature Communications, vol. 9, no. 1, 5288 (2018) . https://doi.org/10.1038/s41467-018-07738-1
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Rudkin, F, Raziunaite, I, Workman, H, Essono, S, Belmonte, R, MacCallum, D M, Johnson, E M, Silva, L M, Palma, A S, Feizi, T, Jensen, A, Erwig, L P & Gow, N A R 2018, ' Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis ', Nature Communications, vol. 9, no. 1, 5288 (2018) . https://doi.org/10.1038/s41467-018-07738-1
FCT Investigator IF/00033/2012. Wellcome Trust (086827, 075470, 099215, 099197 and 101873) Wellcome Trust ISSF award (105625), MRC CiC (MC_PC_14114) and MRC Centre for Medical Mycology and University of Aberdeen for funding and a Wellcome Trust Strat
Autor:
Allan Jensen, Ten Feizi, Neil A. R. Gow, Sosthene Essono, Ingrida Raziunaite, Fiona M. Rudkin, Lisete M. Silva, Lars Erwig, Rodrigo Belmonte, Donna M. MacCallum, H. Workman, Elizabeth M. Johnson, Angelina S. Palma
Publikováno v:
Nature Communications
Rudkin, F M, Raziunaite, I, Workman, H, Essono, S, Belmonte, R, MacCallum, D M, Johnson, E M, Silva, L, Palma, A S, Feizi, T, Jensen, A, Erwig, L P & Gow, N A R 2019, ' Author Correction : Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis ', Nature Communications, vol. 10, no. 1, pp. 394 . https://doi.org/10.1038/s41467-019-08392-x
Nature Communications, Vol 10, Iss 1, Pp 1-2 (2019)
Rudkin, F M, Raziunaite, I, Workman, H, Essono, S, Belmonte, R, MacCallum, D M, Johnson, E M, Silva, L, Palma, A S, Feizi, T, Jensen, A, Erwig, L P & Gow, N A R 2019, ' Author Correction : Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis ', Nature Communications, vol. 10, no. 1, pp. 394 . https://doi.org/10.1038/s41467-019-08392-x
Nature Communications, Vol 10, Iss 1, Pp 1-2 (2019)
The high global burden of over one million annual lethal fungal infections reflects a lack of protective vaccines, late diagnosis and inadequate chemotherapy. Here, we have generated a unique set of fully human anti-Candida monoclonal antibodies (mAb
Autor:
Marina Kovaleva, Ronan O’Dwyer, Caroline J. Barelle, Helen Dooley, Fiona M. Rudkin, Mischa R. Müller
Publikováno v:
Antibody Engineering ISBN: 9781617799730
The drive to exploit novel targets and biological pathways has lead to the expansion of classical antibody research into innovative fragment adaptations and novel scaffolds. The hope being that alternative or cryptic epitopes may be targeted, tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44739a6eddba967b092e8bc91bb33e5e
https://doi.org/10.1007/978-1-61779-974-7_9
https://doi.org/10.1007/978-1-61779-974-7_9
Autor:
Collette Gillespie, Fiona M. Rudkin, Leanne E. Lewis, Neil A. R. Gow, Judith M. Bain, Lars P. Erwig, Christina Lowes
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 8, Iss 3, p e1002578 (2012)
PLoS Pathogens; Vol 8
PLoS Pathogens, Vol 8, Iss 3, p e1002578 (2012)
PLoS Pathogens; Vol 8
Candida albicans is a major life-threatening human fungal pathogen. Host defence against systemic Candida infection relies mainly on phagocytosis of fungal cells by cells of the innate immune system. In this study, we have employed video microscopy,
Autor:
Leanne E Lewis, Judith M Bain, Christina Lowes, Collette Gillespie, Fiona M Rudkin, Neil A R Gow, Lars-Peter Erwig
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3, p e1002578 (2012)
Candida albicans is a major life-threatening human fungal pathogen. Host defence against systemic Candida infection relies mainly on phagocytosis of fungal cells by cells of the innate immune system. In this study, we have employed video microscopy,
Externí odkaz:
https://doaj.org/article/2b1e0b6bca974a3a937a909bcf9ca385