Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fiona M. Chapman"'
Autor:
Ann T. Doherty, George E. Johnson, Fiona M. Chapman, Katherine E. Chapman, Jatin R. Verma, Eleanor C. Wilde, James A. Tonkin, Leanne M. Stannard, Gareth J.S. Jenkins, M. Rowan Brown, Ume-Kulsoom Shah, Anna L. Seager, Shareen H. Doak
Publikováno v:
Archives of Toxicology
Current in vitro genotoxicity tests can produce misleading positive results, indicating an inability to effectively predict a compound’s subsequent carcinogenic potential in vivo. Such oversensitivity can incur unnecessary in vivo tests to further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a23b0c49eed7468aa74bcdecf69813
https://cronfa.swan.ac.uk/Record/cronfa55186/Download/55186__18359__b5f156f08e5d4ed9bbdcc8a37f5027bb.pdf
https://cronfa.swan.ac.uk/Record/cronfa55186/Download/55186__18359__b5f156f08e5d4ed9bbdcc8a37f5027bb.pdf
Autor:
Fiona M. Chapman, Christopher McGuigan, Sahar Kandil, Christophe Pannecouque, Andrew D. Westwell
Human Immunodeficiency Virus (HIV) damages the immune system and leads to the life-threatening acquired immunodeficiency syndrome (AIDS). Despite the advances in the field of antiretroviral treatment, HIV remains a major public health challenge. Nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6b927cbe36819bd2982a15e8a4cec6
https://lirias.kuleuven.be/handle/20.500.12942/687783
https://lirias.kuleuven.be/handle/20.500.12942/687783
Autor:
Gareth J.S. Jenkins, Fiona M. Chapman, David J. Sanders, Chris Sparham, Andrew D. Scott, Roger van Egmond, Katherine E. Chapman, Shareen H. Doak, Colin Hastie
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 67
Genotoxicity testing methods in vitro provide a means to predict the DNA damaging effects of chemicals on human cells. This is hindered in the case of hydrophobic test compounds, however, which will partition to in vitro components such as plastic-wa
Autor:
Fiona M. Chapman, Lucy Swithenbank, Gareth J.S. Jenkins, U. K. Shah, Shareen H. Doak, Katherine E. Chapman
Publikováno v:
The Micronucleus Assay in Toxicology ISBN: 9781788011341
The micronucleus (MN) assay, a mainstay of DNA damage testing for over 30 years, has been applied to dozens of human cell model systems and used to generate hazard identification data on hundreds of chemical (and physical) agents in vitro. Standardis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3411454bd52d6e74d3713308c7fe27c
https://doi.org/10.1039/9781788013604-00169
https://doi.org/10.1039/9781788013604-00169
Autor:
Mathew Hoskins, Edward James, Andrew Paul Smith, Renee Rosky, Andrew D. Westwell, Fiona M. Chapman, Ben Sessa, Jacob Barrow, Thomas L Robertshaw, Michael John Pascoe, Rick Doblin
Publikováno v:
Drug Science, Policy and Law. 7:205032452110349
Background Despite rescheduling of cannabis to Schedule 2 and amendments to the law permitting legal availability of cannabis for the treatment of medical conditions, access to cannabis for medical use remains challenging for patients in the United K
Autor:
Edward James, Thomas L Robertshaw, Michael J Pascoe, Fiona M Chapman, Andrew D Westwell, Andrew P Smith
Publikováno v:
Drug Science, Policy and Law. 5:205032451987612
Background:Contemporary research indicates that the legal classifications of cannabis (Schedule 2, Class B), 3,4-methylenedioxymethamphetamine (MDMA) (Schedule 1, Class A) and psilocybin (Schedule 1, Class A) in the United Kingdom are not entirely ba
Publikováno v:
Eye. 13:674-676
Publikováno v:
Scopus-Elsevier
Studies suggest a link between visual acuity and visual hallucinations in dementia, but links with specific eye pathologies have not been evaluated.Fifty patients (20 with visual hallucinations, 30 without) with probable Alzheimer's disease had an ev
Publikováno v:
BMJ (Clinical research ed.). 318(7182)
EDITOR—Hogg reported a textbook example of a basal cell carcinoma in which biopsy was non-diagnostic.1 The lesion apparently resolved after potent topical steroids were given based on a diagnosis of “sensitivity to PPD, a component of hair dye.