Zobrazeno 1 - 10
of 559
pro vyhledávání: '"Fiona M Watt"'
Autor:
Michele Avissar-Whiting, Frédérique Belliard, Stefano M Bertozzi, Amy Brand, Katherine Brown, Géraldine Clément-Stoneham, Stephanie Dawson, Gautam Dey, Daniel Ecer, Scott C Edmunds, Ashley Farley, Tara D Fischer, Maryrose Franko, James S Fraser, Kathryn Funk, Clarisse Ganier, Melissa Harrison, Anna Hatch, Haley Hazlett, Samantha Hindle, Daniel W Hook, Phil Hurst, Sophien Kamoun, Robert Kiley, Michael M Lacy, Marcel LaFlamme, Rebecca Lawrence, Thomas Lemberger, Maria Leptin, Elliott Lumb, Catriona J MacCallum, Christopher Steven Marcum, Gabriele Marinello, Alex Mendonça, Sara Monaco, Kleber Neves, Damian Pattinson, Jessica K Polka, Iratxe Puebla, Martyn Rittman, Stephen J Royle, Daniela Saderi, Richard Sever, Kathleen Shearer, John E Spiro, Bodo Stern, Dario Taraborelli, Ron Vale, Claudia G Vasquez, Ludo Waltman, Fiona M Watt, Zara Y Weinberg, Mark Williams
Publikováno v:
PLoS Biology, Vol 22, Iss 2, p e3002502 (2024)
Peer review is an important part of the scientific process, but traditional peer review at journals is coming under increased scrutiny for its inefficiency and lack of transparency. As preprints become more widely used and accepted, they raise the po
Externí odkaz:
https://doaj.org/article/f7671182619f4d25a357cd58e213eba8
Autor:
Emanuel Rognoni, Georgina Goss, Toru Hiratsuka, Kalle H Sipilä, Thomas Kirk, Katharina I Kober, Prudence PokWai Lui, Victoria SK Tsang, Nathan J Hawkshaw, Suzanne M Pilkington, Inchul Cho, Niwa Ali, Lesley E Rhodes, Fiona M Watt
Publikováno v:
eLife, Vol 10 (2021)
Solar ultraviolet radiation (UVR) is a major source of skin damage, resulting in inflammation, premature ageing, and cancer. While several UVR-induced changes, including extracellular matrix reorganisation and epidermal DNA damage, have been document
Externí odkaz:
https://doaj.org/article/4829444af2e143fb9fb4e90ef82c6974
Autor:
Mukul Tewary, Dominika Dziedzicka, Joel Ostblom, Laura Prochazka, Nika Shakiba, Tiam Heydari, Daniel Aguilar-Hidalgo, Curtis Woodford, Elia Piccinini, David Becerra-Alonso, Alice Vickers, Blaise Louis, Nafees Rahman, Davide Danovi, Mieke Geens, Fiona M Watt, Peter W Zandstra
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000081 (2019)
In vitro models of postimplantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report characterization of a robust in vitro platform that enabled high-content screening of multiple human
Externí odkaz:
https://doaj.org/article/3d54779845f24e319469e56edbe389d3
Autor:
Chun-Chun Cheng, Ko Tsutsui, Toru Taguchi, Noriko Sanzen, Asako Nakagawa, Kisa Kakiguchi, Shigenobu Yonemura, Chiharu Tanegashima, Sean D Keeley, Hiroshi Kiyonari, Yasuhide Furuta, Yasuko Tomono, Fiona M Watt, Hironobu Fujiwara
Publikováno v:
eLife, Vol 7 (2018)
The heterogeneity and compartmentalization of stem cells is a common principle in many epithelia, and is known to function in epithelial maintenance, but its other physiological roles remain elusive. Here we show transcriptional and anatomical contri
Externí odkaz:
https://doaj.org/article/fea5db47f77942c583134c642d2adbe0
Autor:
Katharina Isabelle Kober, Amparo Cano, Cyrill Géraud, Kalle Sipilä, Seyedeh Atefeh Mobasseri, Christina Philippeos, Angela Oliveira Pisco, Andrew Stannard, Alberto Martin, Fernando Salvador, Vanesa Santos, Michael Boutros, Emanuel Rognoni, Fiona M Watt
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199679 (2018)
Lysyl oxidase-like 2 (LOXL2) is a copper-dependent monoamine oxidase that contributes to the remodelling of the extracellular matrix (ECM) by cross linkage of collagen and elastin fibres and has emerged as a potential therapeutic target in cancer and
Externí odkaz:
https://doaj.org/article/3577d4da62a94bc9957d9343e2fde00e
Autor:
Ajay Mishra, Bénédicte Oulès, Angela Oliveira Pisco, Tony Ly, Kifayathullah Liakath-Ali, Gernot Walko, Priyalakshmi Viswanathan, Matthieu Tihy, Jagdeesh Nijjher, Sara-Jane Dunn, Angus I Lamond, Fiona M Watt
Publikováno v:
eLife, Vol 6 (2017)
Epidermal homeostasis depends on a balance between stem cell renewal and terminal differentiation. The transition between the two cell states, termed commitment, is poorly understood. Here, we characterise commitment by integrating transcriptomic and
Externí odkaz:
https://doaj.org/article/2df07b38696f4e27bfbda3fe780a3c64
Autor:
Mika Watanabe, Ken Natsuga, Wataru Nishie, Yasuaki Kobayashi, Giacomo Donati, Shotaro Suzuki, Yu Fujimura, Tadasuke Tsukiyama, Hideyuki Ujiie, Satoru Shinkuma, Hideki Nakamura, Masamoto Murakami, Michitaka Ozaki, Masaharu Nagayama, Fiona M Watt, Hiroshi Shimizu
Publikováno v:
eLife, Vol 6 (2017)
Type XVII collagen (COL17) is a transmembrane protein located at the epidermal basement membrane zone. COL17 deficiency results in premature hair aging phenotypes and in junctional epidermolysis bullosa. Here, we show that COL17 plays a central role
Externí odkaz:
https://doaj.org/article/de5c2abe4d95455fbf4741ece7554610
Publikováno v:
eLife, Vol 4 (2015)
eLife is introducing a new article type—called Tools and Resources—to highlight new experimental techniques, datasets, software tools and other resources.
Externí odkaz:
https://doaj.org/article/9d279af0a3f24624b0e7b99ce47a10cf
Autor:
Tia DiTommaso, Lynelle K Jones, Denny L Cottle, WTSI Mouse Genetics Program, Anna-Karin Gerdin, Valerie E Vancollie, Fiona M Watt, Ramiro Ramirez-Solis, Allan Bradley, Karen P Steel, John P Sundberg, Jacqueline K White, Ian M Smyth
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004705 (2014)
The skin is a highly regenerative organ which plays critical roles in protecting the body and sensing its environment. Consequently, morbidity and mortality associated with skin defects represent a significant health issue. To identify genes importan
Externí odkaz:
https://doaj.org/article/03c745db72054c98b2c15844f603b5cc
Publikováno v:
eLife, Vol 3 (2014)
eLife has introduced a new type of article–the Research Advance–that allows the authors of an eLife paper to publish results that build on their original research paper.
Externí odkaz:
https://doaj.org/article/08f3b9bf5960412aa4fa7e8d38c2db5a