Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Fiona M Frame"'
Autor:
Rebecca Garnham, Daniel Geh, Ryan Nelson, Erik Ramon-Gil, Laura Wilson, Edward N. Schmidt, Laura Walker, Beth Adamson, Adriana Buskin, Anastasia C. Hepburn, Kirsty Hodgson, Hannah Kendall, Fiona M. Frame, Norman Maitland, Kelly Coffey, Douglas W. Strand, Craig N. Robson, David J. Elliott, Rakesh Heer, Matthew Macauley, Jennifer Munkley, Luke Gaughan, Jack Leslie, Emma Scott
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Immune checkpoint blockade has yet to produce robust anti-cancer responses for prostate cancer. Sialyltransferases have been shown across several solid tumours, including breast, melanoma, colorectal and prostate to promote immune suppressio
Externí odkaz:
https://doaj.org/article/d33390bb279b44abab86eb903fea0a8a
Autor:
Engin Ulukaya, Fiona M Frame, Buse Cevatemre, Davide Pellacani, Hannah Walker, Vincent M Mann, Matthew S Simms, Michael J Stower, Veysel T Yilmaz, Norman J Maitland
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64278 (2013)
The outcome for patients with advanced metastatic and recurrent prostate cancer is still poor. Therefore, new chemotherapeutics are required, especially for killing cancer stem cells that are thought to be responsible for disease recurrence. In this
Externí odkaz:
https://doaj.org/article/fa2ab04b61094a7daa200d16cc8d7ccd
Autor:
Claudia Buhigas, Anne Y. Warren, Wing-Kit Leung, Hayley C. Whitaker, Hayley J. Luxton, Steve Hawkins, Jonathan Kay, Adam Butler, Yaobo Xu, Dan J. Woodcock, Sue Merson, Fiona M. Frame, Atef Sahli, Federico Abascal, CRUK-ICGC Prostate Cancer Group, Iñigo Martincorena, G. Steven Bova, Christopher S. Foster, Peter Campbell, Norman J. Maitland, David E. Neal, Charlie E. Massie, Andy G. Lynch, Rosalind A. Eeles, Colin S. Cooper, David C. Wedge, Daniel S. Brewer
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background Up to 80% of cases of prostate cancer present with multifocal independent tumour lesions leading to the concept of a field effect present in the normal prostate predisposing to cancer development. In the present study we applied W
Externí odkaz:
https://doaj.org/article/ab88a2ce376d486096a3008701e9592f
Autor:
Leanne K. Archer, Fiona M. Frame, Hannah F. Walker, Alastair P. Droop, Georgina L. K. McDonald, Samuel Kucko, Daniel M. Berney, Vincent M. Mann, Matthew S. Simms, Norman J. Maitland
Publikováno v:
FEBS Open Bio, Vol 12, Iss 7, Pp 1365-1387 (2022)
This study aimed to elucidate the role of ELF3, an ETS family member in normal prostate growth and prostate cancer. Silencing ELF3 in both benign prostate (BPH‐1) and prostate cancer (PC3) cell lines resulted in decreased colony‐forming ability,
Externí odkaz:
https://doaj.org/article/aa77d4e3bca64e6fbadf19f5700541d1
Autor:
Conor M. Devlin, Fiona M. Frame, Leanne K. Archer, Vincent M. Mann, Hannah Walker, Matthew S. Simms, Daniel M. Berney, Anne T. Collins, Norman J. Maitland
Publikováno v:
European Urology Open Science, Vol 21, Iss , Pp 29-32 (2020)
Externí odkaz:
https://doaj.org/article/2769066dae164640bd16b32114735e25
Autor:
Rebecca Garnham, Daniel Geh, Ryan Nelson, Erik Ramon-Gill, Laura Wilson, Edward N Schmidt, Laura Walker, Beth Adamson, Adriana Buskin, Anastasia Hepburn, Kirsty Hodgson, Hannah Kendall, Fiona M Frame, Norman Maitland, Kelly Coffey, Craig N Robson, David J Elliott, Rakesh Heer, Matthew Macauley, Jennifer Munkley, Luke Gaughan, Jack Leslie, Emma Scott
Immune checkpoint blockade trials have yet to produce a robust anti-cancer response in prostate cancer patients as a monotherapy due to the immunosuppressed prostate cancer tumour immune microenvironment. ST3Gal1 and other sialyltransferases are impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afd19d74fed230432ab833178839a691
https://doi.org/10.1101/2023.04.03.535346
https://doi.org/10.1101/2023.04.03.535346
Autor:
Anna Dubrovska, Michael Baumann, Norman J. Maitland, Fiona M. Frame, Gustavo B. Baretton, Michael Muders, Marieta Toma, Vladimir Novotny, Gennady D. Telegeev, Eduard A. Stakhovsky, Mechthild Krause, Manfred P. Wirth, Evelin Schröck, Barbara Klink, Franziska Trautmann, Katrin Mäbert, Ina Kurth, Linda Hein, Monica Cojoc, Claudia Peitzsch
Regulation of the genes involved in WNT signaling pathway in the ALDH+ population of DU145 radioresistant (RR) cells versus ALDH- population of DU145 RR cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90156ae620869e1b0ee3a87076027e9a
https://doi.org/10.1158/0008-5472.22411397.v1
https://doi.org/10.1158/0008-5472.22411397.v1
Autor:
Anna Dubrovska, Michael Baumann, Norman J. Maitland, Fiona M. Frame, Gustavo B. Baretton, Michael Muders, Marieta Toma, Vladimir Novotny, Gennady D. Telegeev, Eduard A. Stakhovsky, Mechthild Krause, Manfred P. Wirth, Evelin Schröck, Barbara Klink, Franziska Trautmann, Katrin Mäbert, Ina Kurth, Linda Hein, Monica Cojoc, Claudia Peitzsch
Radiotherapy is a mainstay of curative prostate cancer treatment, but risks of recurrence after treatment remain significant in locally advanced disease. Given that tumor relapse can be attributed to a population of cancer stem cells (CSC) that survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb54c120b6c9fba132aaae8a53744b2e
https://doi.org/10.1158/0008-5472.c.6508217.v1
https://doi.org/10.1158/0008-5472.c.6508217.v1
Autor:
Anna Dubrovska, Michael Baumann, Norman J. Maitland, Fiona M. Frame, Gustavo B. Baretton, Michael Muders, Marieta Toma, Vladimir Novotny, Gennady D. Telegeev, Eduard A. Stakhovsky, Mechthild Krause, Manfred P. Wirth, Evelin Schröck, Barbara Klink, Franziska Trautmann, Katrin Mäbert, Ina Kurth, Linda Hein, Monica Cojoc, Claudia Peitzsch
Description of additional methods and procedures used in the study. Also includes Supplementary Reference.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bf692f6373ee0ddb5657b1618e529b
https://doi.org/10.1158/0008-5472.22411412
https://doi.org/10.1158/0008-5472.22411412
Autor:
Anna Dubrovska, Michael Baumann, Norman J. Maitland, Fiona M. Frame, Gustavo B. Baretton, Michael Muders, Marieta Toma, Vladimir Novotny, Gennady D. Telegeev, Eduard A. Stakhovsky, Mechthild Krause, Manfred P. Wirth, Evelin Schröck, Barbara Klink, Franziska Trautmann, Katrin Mäbert, Ina Kurth, Linda Hein, Monica Cojoc, Claudia Peitzsch
Irradiation-induced changes in the expression of stem cell markers (S1); Genetic alterations in the irradiated prostate cancer cells (S2); Regulation of histone methylation in response to cell irradiation (S3); Differential expression of stem cell an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de26fedfd0d9866426009f7fda42be6
https://doi.org/10.1158/0008-5472.22411418.v1
https://doi.org/10.1158/0008-5472.22411418.v1