Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fiona M, Collier"'
Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity
Autor:
Sheree D. Martin, Timothy Connor, Andrew Sanigorski, Kevin A. McEwen, Darren C. Henstridge, Brunda Nijagal, David De Souza, Dedreia L. Tull, Peter J. Meikle, Greg M. Kowalski, Clinton R. Bruce, Paul Gregorevic, Mark A. Febbraio, Fiona M. Collier, Ken R. Walder, Sean L. McGee
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-13 (2023)
Abstract Lipotoxicity, the accumulation of lipids in non-adipose tissues, alters the metabolic transcriptome and mitochondrial metabolism in skeletal muscle. The mechanisms involved remain poorly understood. Here we show that lipotoxicity increased h
Externí odkaz:
https://doaj.org/article/cb089318d6ca4cdc83eb1a778a2e7a37
Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity
Autor:
Sheree D. Martin, Timothy Connor, Andrew Sanigorski, Kevin A. McEwen, Darren C. Henstridge, Brunda Nijagal, David De Souza, Dedreia L. Tull, Peter J. Meikle, Greg M. Kowalski, Clinton R. Bruce, Paul Gregorevic, Mark A. Febbraio, Fiona M. Collier, Ken R. Walder, Sean L. McGee
Lipotoxicity, the accumulation of lipids in non-adipose tissues, alters the metabolic transcriptome and mitochondrial metabolism in skeletal muscle. The mechanisms involved remain poorly understood. Here we show that lipotoxicity increased histone de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b6269684266e0bcc8f17692dacff11
https://doi.org/10.1101/2022.10.17.512492
https://doi.org/10.1101/2022.10.17.512492
Autor:
Tania J Fernandes, Jason M Hodge, Preetinder P Singh, Damien G Eeles, Fiona M Collier, Ian Holten, Peter R Ebeling, Geoffrey C Nicholson, Julian M W Quinn
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73266 (2013)
In bone, depletion of osteoclasts reduces bone formation in vivo, as does osteal macrophage depletion. How osteoclasts and macrophages promote the action of bone forming osteoblasts is, however, unclear. Since recruitment and differentiation of multi
Externí odkaz:
https://doaj.org/article/b996fcba88014c6eb9e56e026aeadd6f
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21462 (2011)
Macrophage-CSF (M-CSF) is critical for osteoclast (OC) differentiation and is reported to enhance mature OC survival and motility. However, its role in the regulation of bone resorption, the main function of OCs, has not been well characterised. To a
Externí odkaz:
https://doaj.org/article/5e35af53f8344c7fb260abc9b243bfd3
Autor:
Abhilasha, Tiwari, Melinda L, Tursky, Dolly, Mushahary, Samiksha, Wasnik, Fiona M, Collier, Kantipudi, Suma, Mark A, Kirkland, Gopal, Pande
Publikováno v:
Journal of tissue engineering and regenerative medicine. 7(11)
Lineage-specific expansion of haematopoietic stem/progenitor cells (HSPCs) from human umbilical cord blood (UCB) is desirable because of their several applications in translational medicine, e.g. treatment of cancer, bone marrow failure and immunodef