Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Fiona L. L. Stratford"'
Autor:
Mohabir Ramjeesingh, Christine E. Bear, Ling-Jun Huan, Francisca Ugwu, Fiona L. L. Stratford, Canhui Li
Publikováno v:
Biochemical Journal. 412:315-321
The two NBDs (nucleotide-binding domains) of ABC (ATP-binding-cassette) proteins function in a complex to mediate ATPase activity and this activity has been linked to their regulated transport activity. A similar model has been proposed for CFTR (cys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ba6e50307ea6517f489a893f244906
https://doi.org/10.1042/bj20071719
https://doi.org/10.1042/bj20071719
Autor:
Fiona L. L. Stratford, Jody Parker, Malcolm Martin Claude Pereira, Margaret A. McPherson, Robert L. Dormer
Publikováno v:
Biochemical Journal. 405:181-189
The CFTR [CF (cystic fibrosis) transmembrane conductance regulator] chloride channel is activated by cyclic nucleotide-dependent phosphorylation and ATP binding, but also by non-phosphorylation-dependent mechanisms. Other CFTR functions such as regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fbc08dfea692e712daab3a3e877fec
https://doi.org/10.1042/bj20061879
https://doi.org/10.1042/bj20061879
Autor:
Paul Brooks, Katia Forti, Fiona L. L. Stratford, Alexander J. Pemberton, A. Jennifer Rivett, Suchira Bose, David Onion, David Shirley
Publikováno v:
Experimental Gerontology. 37:1217-1222
Proteasomes play a major role in intracellular protein turnover. They exist in cells in several different molecular forms including 20S proteasomes, 26S proteasomes and PA28-20S proteasome complexes. In this study we have compared the properties of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba3962f15070420a8704efe3662d646
https://doi.org/10.1016/s0531-5565(02)00127-4
https://doi.org/10.1016/s0531-5565(02)00127-4
Autor:
Bertrand Friguet, Fiona L. L. Stratford, Niki Chondrogianni, Efstathios S. Gonos, A. Jennifer Rivett, Ioannis P. Trougakos
Publikováno v:
Free Radical Research 37 112-112
Normal human fibroblasts undergo a limited number of divisions in culture and progressively they reach a state of irreversible growth arrest, a process termed as replicative senescence. The proteasome is the major cellular proteolytic machinery, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9150b877e7a70b4f567fea7755a66640
http://helios-eie.ekt.gr/EIE/handle/10442/2971
http://helios-eie.ekt.gr/EIE/handle/10442/2971
Autor:
Ling-Jun Huan, Joanne C. Cheung, Christine E. Bear, Fiona L. L. Stratford, Mohabir Ramjeesingh
Publikováno v:
The Biochemical journal. 401(2)
CFTR (cystic fibrosis transmembrane conductance regulator), a member of the ABC (ATP-binding cassette) superfamily of membrane proteins, possesses two NBDs (nucleotide-binding domains) in addition to two MSDs (membrane spanning domains) and the regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f3a77b3da2fe5899f3842495bd606d
https://pubmed.ncbi.nlm.nih.gov/16989640
https://pubmed.ncbi.nlm.nih.gov/16989640
Autor:
Hsin-Hen Kuo, Charles M. Deber, Fiona L. L. Stratford, Leigh Wellhauser, Canhui Li, Winnie Luong, Ling-Jun Huan, Christine E. Bear, Mohabir Ramjeesingh
Publikováno v:
The Biochemical journal. 398(2)
Mutations in ClC-5 (chloride channel 5), a member of the ClC family of chloride ion channels and antiporters, have been linked to Dent's disease, a renal disease associated with proteinuria. Several of the disease-causing mutations are premature stop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb38ae570b31709824d9075f3d83344
https://pubmed.ncbi.nlm.nih.gov/16686597
https://pubmed.ncbi.nlm.nih.gov/16686597
Autor:
Ioannis P. Trougakos, Niki Chondrogianni, A. Jennifer Rivett, Efstathios S. Gonos, Fiona L. L. Stratford
Publikováno v:
FEBS letters. 580(16)
We have investigated immunoproteasomes in human fibroblasts during replicative senescence. Unlike levels of constitutive proteasome catalytic subunits and 26S proteasome regulatory subunits, levels of immunosubunits did not decrease dramatically in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c51d00fbbc6158a9cf29705523e87fd
https://pubmed.ncbi.nlm.nih.gov/16806194
https://pubmed.ncbi.nlm.nih.gov/16806194
Autor:
A. Jennifer Rivett, Grant G. F. Mason, Kerry I. Broadfoot, Fiona L. L. Stratford, Suchira Bose
Publikováno v:
The Biochemical journal. 378(Pt 1)
In animal cells there are several regulatory complexes which interact with 20S proteasomes and give rise to functionally distinct proteasome complexes. gamma-Interferon upregulates three immuno beta catalytic subunits of the 20S proteasome and the PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55da2729fbdd7e8d3b94e6f158e4ede7
https://pubmed.ncbi.nlm.nih.gov/14583091
https://pubmed.ncbi.nlm.nih.gov/14583091
Autor:
Niki, Chondrogianni, Fiona L L, Stratford, Ioannis P, Trougakos, Bertrand, Friguet, A Jennifer, Rivett, Efstathios S, Gonos
Publikováno v:
The Journal of biological chemistry. 278(30)
Normal human fibroblasts undergo a limited number of divisions in culture and progressively they reach a state of irreversible growth arrest, a process termed as replicative senescence. The proteasome is the major cellular proteolytic machinery, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac20ca85b960c12c276544f08debfc83
https://pubmed.ncbi.nlm.nih.gov/12736271
https://pubmed.ncbi.nlm.nih.gov/12736271
Autor:
Margaret A. McPherson, Robert L. Dormer, Fiona L. L. Stratford, Frédéric Becq, Malcolm M.C. Pereira
Publikováno v:
Biochemical and biophysical research communications. 300(2)
Proteins comprising the first nucleotide-binding- and R-domains of wild-type and Delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) have been synthesised by in vitro transcription/translation. The kinetics and extent of degradation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9abf12154acb64276882fbd1232e012b
https://pubmed.ncbi.nlm.nih.gov/12504115
https://pubmed.ncbi.nlm.nih.gov/12504115