Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Fiona Kupresanin"'
Autor:
Pablo A. Silveira, Fiona Kupresanin, Adelina Romano, Wei-Hsun Hsu, Tsun-Ho Lo, Xinsheng Ju, Hsiao-Ting Chen, Helen Roberts, Daniel G. Baker, Georgina J. Clark
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antibodies targeting the activation marker CD83 can achieve immune suppression by targeting antigen-presenting mature dendritic cells (DC). This study investigated the immunosuppressive mechanisms of anti-CD83 antibody treatment in mice and tested it
Externí odkaz:
https://doaj.org/article/b71c3ee5e94f4cca9f993daa274505a7
Autor:
Edward Abadir, Robin E. Gasiorowski, Kaitao Lai, Fiona Kupresanin, Adelina Romano, Pablo A. Silveira, Tsun‐Ho Lo, Phillip D. Fromm, Marina L. Kennerson, Harry J. Iland, P. Joy Ho, P. Mark Hogarth, Kenneth Bradstock, Derek N.J. Hart, Georgina J. Clark
Publikováno v:
Molecular Oncology, Vol 13, Iss 10, Pp 2107-2120 (2019)
Antibody‐based therapy in acute myeloid leukemia (AML) has been marred by significant hematologic toxicity due to targeting of both hematopoietic stem and progenitor cells (HSPCs). Achieving greater success with therapeutic antibodies requires care
Externí odkaz:
https://doaj.org/article/45bf9c7fc9c74c24a8afac22a249fba2
Autor:
Charis E. Teh, Najoua Lalaoui, Reema Jain, Antonia N. Policheni, Melanie Heinlein, Silvia Alvarez-Diaz, Julie M. Sheridan, Eva Rieser, Stefanie Deuser, Maurice Darding, Hui-Fern Koay, Yifang Hu, Fiona Kupresanin, Lorraine A. O’Reilly, Dale I. Godfrey, Gordon K. Smyth, Philippe Bouillet, Andreas Strasser, Henning Walczak, John Silke, Daniel H. D. Gray
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
LUBAC is a ubiquitin ligase complex of HOIL-1, HOIP and SHARPIN important for signal transduction of a range of stimuli. Here the authors define the function of all three LUBAC components in T cell development and homeostasis.
Externí odkaz:
https://doaj.org/article/c1d02d8f3cfd4e61aaa53ba2e9e08e3d
Autor:
Tsun-Ho Lo, Edward Abadir, Robin E Gasiorowski, Karieshma Kabani, Murari Ramesh, Daniel Orellana, Phillip D Fromm, Fiona Kupresanin, Elizabeth Newman, Ilona Cunningham, Derek N J Hart, Pablo A Silveira, Georgina J Clark
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216368 (2019)
Acute myeloid leukemia (AML) is the most common form of adult acute leukemia with ~20,000 new cases yearly. The disease develops in people of all ages, but is more prominent in the elderly, who due to limited treatment options, have poor overall surv
Externí odkaz:
https://doaj.org/article/75649774d1c04dbaafc3e41c4a7c1ba6
Autor:
Ziduo Li, Xinsheng Ju, Kenneth Lee, Candice Clarke, Jennifer L. Hsu, Edward Abadir, Christian E. Bryant, Suzanne Pears, Neroli Sunderland, Scott Heffernan, Annemarie Hennessy, Tsun-Ho Lo, Geoffrey A. Pietersz, Fiona Kupresanin, Phillip D. Fromm, Pablo A. Silveira, Con Tsonis, Wendy A. Cooper, Ilona Cunningham, Christina Brown, Georgina J. Clark, Derek N.J. Hart
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Chemotherapy and hematopoietic stem cell transplantation are effective treatments for most Hodgkin lymphoma patients, however there remains a need for better tumor-specific target therapy in Hodgkin lymphoma patients with refractory or relapsed disea
Externí odkaz:
https://doaj.org/article/63f149b189ae42c788167b1de64141fd
Autor:
Adele M Mount, Christopher M Smith, Fiona Kupresanin, Kristina Stoermer, William R Heath, Gabrielle T Belz
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1691 (2008)
Dendritic cells (DC) are a heterogeneous cell population that bridge the innate and adaptive immune systems. CD8alpha DC play a prominent, and sometimes exclusive, role in driving amplification of CD8(+) T cells during a viral infection. Whether this
Externí odkaz:
https://doaj.org/article/b0670517b7d04f0cbd6247285c948ccd
Autor:
Michael S. Papadimitrious, Christian E Bryant, Derek N.J. Hart, Tsun-Ho Lo, Pablo A. Silveira, Ahmed H. Mekkawy, Xinsheng Ju, Barbara Fazekas de St Groth, Phillip D. Fromm, John Gibson, Elizabeth Newman, Helen M. McGuire, Jennifer Hsu, Adelina Romano, Georgina J. Clark, Fiona Kupresanin, Ilona Cunningham, Benjamin Y. Kong, Wei-Hsun Hsu, P. Mark Hogarth, Edward Abadir
Publikováno v:
Journal of Leukocyte Biology. 107:323-339
Myeloid lineage cells present in human peripheral blood include dendritic cells (DC) and monocytes. The DC are identified phenotypically as HLA-DR+ cells that lack major cell surface lineage markers for T cells (CD3), B cells (CD19, CD20), NK cells (
Autor:
Pablo A. Silveira, Fiona Kupresanin, Adelina Romano, Wei-Hsun Hsu, Tsun-Ho Lo, Xinsheng Ju, Hsiao-Ting Chen, Helen Roberts, Daniel G. Baker, Georgina J. Clark
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antibodies targeting the activation marker CD83 can achieve immune suppression by targeting antigen-presenting mature dendritic cells (DC). This study investigated the immunosuppressive mechanisms of anti-CD83 antibody treatment in mice and tested it
Autor:
Melanie Heinlein, John Silke, Cathrine Hall, Daniel H.D. Gray, Reema Jain, Andreas Strasser, Julie Sheridan, Henning Walczak, Fiona Kupresanin, James A Rickard, Kelin Zhao, Philippe Bouillet, Waruni Abeysekera
Publikováno v:
Cell Death Differ
Thymic epithelial cells (TECs) form a unique microenvironment that orchestrates T cell differentiation and immunological tolerance. Despite the importance of TECs for adaptive immunity, there is an incomplete understanding of the signalling networks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915b19c0bdbc9fd213c0dc3fc5d4d28d
https://europepmc.org/articles/PMC8481470/
https://europepmc.org/articles/PMC8481470/
Autor:
P. Joy Ho, Kenneth F. Bradstock, Tsun-Ho Lo, Phillip D. Fromm, Harry J. Iland, Derek N.J. Hart, Adelina Romano, Fiona Kupresanin, Marina L. Kennerson, Kaitao Lai, Robin Gasiorowski, Georgina J. Clark, Edward Abadir, Pablo A. Silveira, P. Mark Hogarth
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 13, Iss 10, Pp 2107-2120 (2019)
Molecular Oncology, Vol 13, Iss 10, Pp 2107-2120 (2019)
Antibody‐based therapy in acute myeloid leukemia (AML) has been marred by significant hematologic toxicity due to targeting of both hematopoietic stem and progenitor cells (HSPCs). Achieving greater success with therapeutic antibodies requires care