Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Fiona J. E. Morgan"'
Autor:
Ewan M. Harrison, Lucy A. Weinert, Matthew T. G. Holden, John J. Welch, Katherine Wilson, Fiona J. E. Morgan, Simon R. Harris, Anette Loeffler, Amanda K. Boag, Sharon J. Peacock, Gavin K. Paterson, Andrew S. Waller, Julian Parkhill, Mark A. Holmes
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) is a global human health problem causing infections in both hospitals and the community. Companion animals, such as cats, dogs, and horses, are also frequently colonized by MRSA and can beco
Externí odkaz:
https://doaj.org/article/23eef690f87e4e0495719494f04dd758
Autor:
Jesper Larsen, Claire L. Raisen, Xiaoliang Ba, Nicholas J. Sadgrove, Guillermo F. Padilla-González, Monique S. J. Simmonds, Igor Loncaric, Heidrun Kerschner, Petra Apfalter, Rainer Hartl, Ariane Deplano, Stien Vandendriessche, Barbora Černá Bolfíková, Pavel Hulva, Maiken C. Arendrup, Rasmus K. Hare, Céline Barnadas, Marc Stegger, Raphael N. Sieber, Robert L. Skov, Andreas Petersen, Øystein Angen, Sophie L. Rasmussen, Carmen Espinosa-Gongora, Frank M. Aarestrup, Laura J. Lindholm, Suvi M. Nykäsenoja, Frederic Laurent, Karsten Becker, Birgit Walther, Corinna Kehrenberg, Christiane Cuny, Franziska Layer, Guido Werner, Wolfgang Witte, Ivonne Stamm, Paolo Moroni, Hannah J. Jørgensen, Hermínia de Lencastre, Emilia Cercenado, Fernando García-Garrote, Stefan Börjesson, Sara Hæggman, Vincent Perreten, Christopher J. Teale, Andrew S. Waller, Bruno Pichon, Martin D. Curran, Matthew J. Ellington, John J. Welch, Sharon J. Peacock, David J. Seilly, Fiona J. E. Morgan, Julian Parkhill, Nazreen F. Hadjirin, Jodi A. Lindsay, Matthew T. G. Holden, Giles F. Edwards, Geoffrey Foster, Gavin K. Paterson, Xavier Didelot, Mark A. Holmes, Ewan M. Harrison, Anders R. Larsen
Publikováno v:
Larsen, Jesper; Raisen, Claire L; Ba, Xiaoliang; Sadgrove, Nicholas J; Padilla-González, Guillermo F; Simmonds, Monique S J; Loncaric, Igor; Kerschner, Heidrun; Apfalter, Petra; Hartl, Rainer; Deplano, Ariane; Vandendriessche, Stien; Černá Bolfíková, Barbora; Hulva, Pavel; Arendrup, Maiken C; Hare, Rasmus K; Barnadas, Céline; Stegger, Marc; Sieber, Raphael N; Skov, Robert L; ... (2022). Emergence of methicillin resistance predates the clinical use of antibiotics. Nature, 602(7895), pp. 135-141. Springer Nature Limited 10.1038/s41586-021-04265-w
Larsen, J, Raisen, C L, Sadgrove, N J, Padilla-González, G F, Simmonds, M S J, Loncaric, I, Kerschner, H, Apfalter, P, Hartl, R, Ariane Deplano, A, Vandendriessche, S, Bolfíková, B Č, Hulva, P, Arendrup, M C, Hare, R K, Barnadas, C, Stegger, M, Sieber, R N, Skov, R L, Petersen, A, Angen, Ø, Rasmussen, S L, Espinosa-Gongora, C, Aarestrup, F M, Lindholm, L, Nykäsenoja, S, Laurent, F, Becker, K, Walther, B, Kehrenberg, C, Cuny, C, Layer, F, Werner, G, Witte, W, Stamm, I, Moroni, P, Jørgensen, H, de Lencastre, H, Cercenado, E, García-Garrote, F, Börjesson, S, Hæggman, S, Perreten, V, J. Teale, C, Waller, A, Pichon, B, Curran, M, Ellington, M, Welch, J, Peacock, S, Seilly, D, Morgan, F, Parkhill, J, Hadjirin, N, Lindsay, J, Holden, M T G, Edwards, G F, Foster, G, Paterson, G, Didelot, X, Holmes, M, Harrison, E & Larsen, A R 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, no. 7895, pp. 135-141 . https://doi.org/10.1038/s41586-021-04265-w
Larsen, J, Raisen, C L, Ba, X, Sadgrove, N J, Padilla-González, G F, Simmonds, M S J, Loncaric, I, Kerschner, H, Apfalter, P, Hartl, R, Deplano, A, Vandendriessche, S, Černá Bolfíková, B, Hulva, P, Arendrup, M C, Hare, R K, Barnadas, C, Stegger, M, Sieber, R N, Skov, R L, Petersen, A, Angen, Ø, Rasmussen, S L, Espinosa-Gongora, C, Aarestrup, F M, Lindholm, L J, Nykäsenoja, S M, Laurent, F, Becker, K, Walther, B, Kehrenberg, C, Cuny, C, Layer, F, Werner, G, Witte, W, Stamm, I, Moroni, P, Jørgensen, H J, de Lencastre, H, Cercenado, E, García-Garrote, F, Börjesson, S, Hæggman, S, Perreten, V, Teale, C J, Waller, A S, Pichon, B, Curran, M D, Ellington, M J, Welch, J J, Peacock, S J, Seilly, D J, Morgan, F J E, Parkhill, J, Hadjirin, N F, Lindsay, J A, Holden, M T G, Edwards, G F, Foster, G, Paterson, G K, Didelot, X, Holmes, M A, Harrison, E M & Larsen, A R 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, pp. 135–141 . https://doi.org/10.1038/s41586-021-04265-w
Paterson, G K 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, pp. 135-141 . https://doi.org/10.1038/s41586-021-04265-w
Larsen, J, Raisen, C L, Sadgrove, N J, Padilla-González, G F, Simmonds, M S J, Loncaric, I, Kerschner, H, Apfalter, P, Hartl, R, Ariane Deplano, A, Vandendriessche, S, Bolfíková, B Č, Hulva, P, Arendrup, M C, Hare, R K, Barnadas, C, Stegger, M, Sieber, R N, Skov, R L, Petersen, A, Angen, Ø, Rasmussen, S L, Espinosa-Gongora, C, Aarestrup, F M, Lindholm, L, Nykäsenoja, S, Laurent, F, Becker, K, Walther, B, Kehrenberg, C, Cuny, C, Layer, F, Werner, G, Witte, W, Stamm, I, Moroni, P, Jørgensen, H, de Lencastre, H, Cercenado, E, García-Garrote, F, Börjesson, S, Hæggman, S, Perreten, V, J. Teale, C, Waller, A, Pichon, B, Curran, M, Ellington, M, Welch, J, Peacock, S, Seilly, D, Morgan, F, Parkhill, J, Hadjirin, N, Lindsay, J, Holden, M T G, Edwards, G F, Foster, G, Paterson, G, Didelot, X, Holmes, M, Harrison, E & Larsen, A R 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, no. 7895, pp. 135-141 . https://doi.org/10.1038/s41586-021-04265-w
Larsen, J, Raisen, C L, Ba, X, Sadgrove, N J, Padilla-González, G F, Simmonds, M S J, Loncaric, I, Kerschner, H, Apfalter, P, Hartl, R, Deplano, A, Vandendriessche, S, Černá Bolfíková, B, Hulva, P, Arendrup, M C, Hare, R K, Barnadas, C, Stegger, M, Sieber, R N, Skov, R L, Petersen, A, Angen, Ø, Rasmussen, S L, Espinosa-Gongora, C, Aarestrup, F M, Lindholm, L J, Nykäsenoja, S M, Laurent, F, Becker, K, Walther, B, Kehrenberg, C, Cuny, C, Layer, F, Werner, G, Witte, W, Stamm, I, Moroni, P, Jørgensen, H J, de Lencastre, H, Cercenado, E, García-Garrote, F, Börjesson, S, Hæggman, S, Perreten, V, Teale, C J, Waller, A S, Pichon, B, Curran, M D, Ellington, M J, Welch, J J, Peacock, S J, Seilly, D J, Morgan, F J E, Parkhill, J, Hadjirin, N F, Lindsay, J A, Holden, M T G, Edwards, G F, Foster, G, Paterson, G K, Didelot, X, Holmes, M A, Harrison, E M & Larsen, A R 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, pp. 135–141 . https://doi.org/10.1038/s41586-021-04265-w
Paterson, G K 2022, ' Emergence of methicillin resistance predates the clinical use of antibiotics ', Nature, vol. 602, pp. 135-141 . https://doi.org/10.1038/s41586-021-04265-w
X.D. was funded by a grant from the National Institute for Health Research (NIHR) Health Protection Research Unit in Genomics and Enabling Data (no. NIHR200892). M.A.H. was supported by grants from the Medical Research Council (nos. G1001787/1, MR/N0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c43e8cd39a109234141bcbc266c126
Autor:
David M Bulmer, Lubna Kharraz, Andrew J Grant, Paul Dean, Fiona J E Morgan, Michail H Karavolos, Anne C Doble, Emma J McGhie, Vassilis Koronakis, Richard A Daniel, Pietro Mastroeni, C M Anjam Khan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)
Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit
Externí odkaz:
https://doaj.org/article/0e54051753e7417a9ab0ff1ecf95a74a
Autor:
Fiona J. E. Morgan, Raphaelle Taub, Eugenia Cammarota, Chiara Soriani, Clare E. Bryant, Sarah L. Veatch, Pietro Cicuta, Jiro Sakai
Publikováno v:
Journal of the Royal Society Interface
Signalling is of particular importance in immune cells, and upstream in the signalling pathway many membrane receptors are functional only as complexes, co-locating with particular lipid species. Work over the last 15 years has shown that plasma memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b57891985826b92957668c4d685331
Autor:
Michail H. Karavolos, Pietro Mastroeni, Lubna Kharraz, David M. Bulmer, Emma J. McGhie, Fiona J. E. Morgan, Paul Dean, Andrew J. Grant, Anne C. Doble, Vassilis Koronakis, Richard A. Daniel, C. M. Anjam Khan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)
PLoS Pathogens
PLoS Pathogens
Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c9c9b343cebceab62e914a8246c9d8
Autor:
Gavin K. Paterson, Petra Apfalter, Fiona J. E. Morgan, Rui Zhou, Xiaoliang Ba, Samantha L Girvan, Nazreen F. Hadjirin, Ewan M. Harrison, Lajos Kalmar, Mark A. Holmes, Heidrun Kerschner
Publikováno v:
Ba, X, Kalmar, L, Hadjirin, N, Kerschner, H, Apfalter, P, Morgan, F, Paterson, G, Girvan, S, Zhou, R, Harrison, E M & Holmes, M A 2019, ' Truncation of GdpP mediates β-lactam resistance in clinical isolates of Staphylococcus aureus ', Journal of Antimicrobial Chemotherapy . https://doi.org/10.1093/jac/dkz013
Objectives: High-level β-lactam resistance in methicillin-resistant Staphylococcus aureus is mediated in the majority of strains by a mecA or mecC gene. In this study, we identified ten mec gene negative MRSA human isolates from Austria and eleven b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60095faf6850308f7896d7579b4e04f
https://www.pure.ed.ac.uk/ws/files/78960058/Truncation_of_GdpP_mediates_lactam_resistance_in_clinical_isolates_of_Staphylococcus_aureus_accepted.docx
https://www.pure.ed.ac.uk/ws/files/78960058/Truncation_of_GdpP_mediates_lactam_resistance_in_clinical_isolates_of_Staphylococcus_aureus_accepted.docx
Autor:
Edward J. P. Cartwright, Sharon J. Peacock, Ewan M. Harrison, Fiona J. E. Morgan, Ruth N. Zadoks, Mark A. Holmes, M. E. Török, Julian Parkhill, Gavin K. Paterson
Publikováno v:
Journal of Antimicrobial Chemotherapy. 69:907-910
Objectives: There are limited data available on the epidemiology and prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in the human population that encode the recently described mecA homologue, mecC. To address this knowledge gap we un
Autor:
Julian Parkhill, Mark A. Holmes, Ewan M. Harrison, Sharon J. Peacock, Fiona J. E. Morgan, Gavin K. Paterson, Ruth N. Zadoks
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives mecC methicillin-resistant Staphylococcus aureus (MRSA) represent a newly recognized form of MRSA, distinguished by the possession of a divergent mecA homologue, mecC. The first isolate to be identified came from bovine milk, but there are
Autor:
Victoria F. John, Robert A. Kingsley, Gordon Dougan, Carole Janis, Andrew J. Grant, Jenny Houghton, Fiona J. E. Morgan, Trevelyan J. McKinley, Pietro Mastroeni
Publikováno v:
Infection and Immunity. 79:2481-2488
Salmonella enterica serovar Typhi, the agent of typhoid fever in humans, expresses the surface Vi polysaccharide antigen that contributes to virulence. However, Vi expression can also be detrimental to some key steps of S. Typhi infectivity, for exam
Autor:
Simon Clare, Ewan Shawcroft, Duncan J. Maskell, Pietro Mastroeni, Fiona J. E. Morgan, Trevelyan J. McKinley, Andrew J. Grant
Publikováno v:
Infection and Immunity. 79:636-643
The interaction between Salmonella enterica and the host immune system is complex. The outcome of an infection is the result of a balance between the in vivo environment where the bacteria survive and grow and the regulation of fitness genes at a lev