Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Fiona J Radcliff"'
Autor:
Ries J Langley, Yi Tian Ting, Fiona Clow, Paul G Young, Fiona J Radcliff, Jeong Min Choi, Richard P Sequeira, Silva Holtfreter, Heather Baker, John D Fraser
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006549 (2017)
Staphylococcus aureus is an opportunistic pathogen that produces many virulence factors. Two major families of which are the staphylococcal superantigens (SAgs) and the Staphylococcal Superantigen-Like (SSL) exoproteins. The former are immunomodulato
Externí odkaz:
https://doaj.org/article/40b9902d97ac42128986edcdb616c876
Publikováno v:
Vaccines, Vol 7, Iss 4, p 191 (2019)
Development of a vaccine to limit the impact of antibiotic resistant Neisseria gonorrhoeae is now a global priority. Serum bactericidal antibody (SBA) is a possible indicator of protective immunity to N. gonorrhoeae, but conventional assays measure c
Externí odkaz:
https://doaj.org/article/e0a96a46339c44059c7b38c1baadf702
Autor:
Fiona J Radcliff, Sharon Waldvogel-Thurlow, Fiona Clow, Murali Mahadevan, James Johnston, Gen Li, Thomas Proft, Richard G Douglas, John D Fraser
Publikováno v:
Pathogens, Vol 8, Iss 3, p 90 (2019)
Staphylococcus aureus and Group A Streptococcus (GAS) are common occupants of the tonsils and many strains produce potent exotoxins (mitogens) that directly target T cells, which could be a driver for tonsillar hyperplasia. Tonsil tissues from 41 pat
Externí odkaz:
https://doaj.org/article/09b06b73edee4eb8b6de73a4ef5964f9
Autor:
Silva Holtfreter, Fiona J Radcliff, Dorothee Grumann, Hannah Read, Sarah Johnson, Stefan Monecke, Stephen Ritchie, Fiona Clow, Christiane Goerke, Barbara M Bröker, John D Fraser, Siouxsie Wiles
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e71142 (2013)
More effective antibiotics and a protective vaccine are desperately needed to combat the 'superbug' Staphylococcus aureus. While in vivo pathogenicity studies routinely involve infection of mice with human S. aureus isolates, recent genetic studies h
Externí odkaz:
https://doaj.org/article/2177ecd54e1043b6aec02362dcae7e77
Autor:
Brett Wagner Mackenzie, Melissa Zoing, Fiona Clow, David W. Waite, Fiona J. Radcliff, Michael W. Taylor, Kristi Biswas, Richard G. Douglas
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The role of Staphylococcus aureus in the pathogenesis of the chronic sinonasal disease chronic rhinosinusitis (CRS), has not been definitively established. Comparative analyses of S. aureus isolates from CRS with those from control participa
Externí odkaz:
https://doaj.org/article/fa0bbe6bbdc04bf4a4adf456bbc8008c
Autor:
Kristi Biswas, David W. Waite, Melissa Zoing, Michael W. Taylor, Fiona J. Radcliff, Fiona Clow, Brett Wagner Mackenzie, Richard G. Douglas
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
The role of Staphylococcus aureus in the pathogenesis of the chronic sinonasal disease chronic rhinosinusitis (CRS), has not been definitively established. Comparative analyses of S. aureus isolates from CRS with those from control participants may o
Publikováno v:
Immunology and cell biology. 100(3)
The group A Streptococcus (GAS) pilus is a long, flexible, hair-like structure anchored to the cell surface that facilitates the adherence of GAS to host cells, thus playing a critical role in initiating infections. Because of its important role in G
Autor:
Brett Wagner Mackenzie, Kristi Biswas, Richard G. Douglas, Fiona J. Radcliff, Stephen Ball, Satya Amirapu
Publikováno v:
International Journal of Otolaryngology, Vol 2021 (2021)
International Journal of Otolaryngology
International Journal of Otolaryngology
The purpose of this review is to summarise contemporary knowledge of sinonasal tissue remodelling during chronic rhinosinusitis (CRS), a chronic disease involving long-term inflammation of the paranasal sinuses and nasal passage. The concept of tissu
Autor:
Kristi Biswas, Richard G. Douglas, Carmen Astudillo-García, Michael Hoggard, Fiona J. Radcliff, James Johnston, Murali Mahadevan
Publikováno v:
International Journal of Pediatric Otorhinolaryngology. 113:51-57
Culture-independent methods, based on bacterial 16 S rRNA gene sequencing, have been used previously to investigate the adenotonsillar microbiota. However, these studies have focused on a single sampling site (usually a surface swab). We aimed to inv
Autor:
Michael Hoggard, Sharon Waldvogel-Thurlow, James Johnston, Carmen Astudillo-García, Richard G. Douglas, Kristi Biswas, Fiona J. Radcliff, Murali Mahadevan
Publikováno v:
International Journal of Pediatric Otorhinolaryngology. 113:281-288
Introduction Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA