Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Fiona J, Warner"'
Autor:
Christine Yee, Nathan M Main, Alexandra Terry, Igor Stevanovski, Annette Maczurek, Alison J Morgan, Sarah Calabro, Alison J Potter, Tina L Iemma, David G Bowen, Golo Ahlenstiel, Fiona J Warner, Geoffrey W McCaughan, Susan V McLennan, Nicholas A Shackel
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0215557 (2019)
BackgroundChronic inflammation is the driver of liver injury and results in progressive fibrosis and eventual cirrhosis with consequences including both liver failure and liver cancer. We have previously described increased expression of the highly m
Externí odkaz:
https://doaj.org/article/d0940ab7fa584a72b7bc28e44329defd
Novel Aspects of the Liver Microenvironment in Hepatocellular Carcinoma Pathogenesis and Development
Autor:
Thomas Tu, Magdalena A. Budzinska, Annette E. Maczurek, Robert Cheng, Anna Di Bartolomeo, Fiona J. Warner, Geoffrey W. McCaughan, Susan V. McLennan, Nicholas A. Shackel
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 6, Pp 9422-9458 (2014)
Hepatocellular carcinoma (HCC) is a prevalent primary liver cancer that is derived from hepatocytes and is characterised by high mortality rate and poor prognosis. While HCC is driven by cumulative changes in the hepatocyte genome, it is increasingly
Externí odkaz:
https://doaj.org/article/98be9c65a75a43f2a0ac1ae7a2e2fde8
Autor:
Sarah R Calabro, Annette E Maczurek, Alison J Morgan, Thomas Tu, Victoria W Wen, Christine Yee, Auvro Mridha, Maggie Lee, William d'Avigdor, Stephen A Locarnini, Geoffrey W McCaughan, Fiona J Warner, Susan V McLennan, Nicholas A Shackel
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e90571 (2014)
The classical paradigm of liver injury asserts that hepatic stellate cells (HSC) produce, remodel and turnover the abnormal extracellular matrix (ECM) of fibrosis via matrix metalloproteinases (MMPs). In extrahepatic tissues MMP production is regulat
Externí odkaz:
https://doaj.org/article/5fb65a4f64194cb481221ea58bfb0859
Autor:
Christine Yee, Alison J. Potter, S.R. Calabro, Alexandra M. Terry, Geoffrey W. McCaughan, Igor Stevanovski, Annette E. Maczurek, Nicholas A. Shackel, Golo Ahlenstiel, David G. Bowen, Susan V. McLennan, A.J. Morgan, Tina L. Iemma, Nathan M. Main, Fiona J. Warner
BackgroundChronic inflammation is the driver of liver injury resulting in progressive fibrosis and eventual cirrhosis. The consequences include both liver failure and liver cancer. We have previously described increased expression of the highly multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01329334b7957896721266f62c2c637
Autor:
S.R. Calabro, Nicholas A. Shackel, Tina L. Iemma, Igor Stevanovski, Fiona J. Warner, Golo Ahlenstiel, Geoffrey W. McCaughan, A.J. Morgan, Susan V. McLennan, Nathan M. Main, Christine Yee, Alexandra M. Terry, Annette E. Maczurek, David G. Bowen, Alison J. Potter
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0215557 (2019)
PLoS ONE
PLoS ONE
BackgroundChronic inflammation is the driver of liver injury and results in progressive fibrosis and eventual cirrhosis with consequences including both liver failure and liver cancer. We have previously described increased expression of the highly m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c213ceb848031d5d80440d1ebc8a91b7
https://hdl.handle.net/10453/162889
https://hdl.handle.net/10453/162889
Autor:
Ian Kronborg, Niranjan Arachchi, Susan V. McLennan, Geoffrey W. McCaughan, A. Rode, Fiona J. Warner, Amanda Nicoll, Annette E. Maczurek, Seok Lim, Alexandra Gorelik, A. Lee, Nicholas A. Shackel, Danny Liew, Lucy Lim, Peter W Angus
Publikováno v:
Journal of Gastroenterology and Hepatology. 31:459-466
Background and Aim: The glycoprotein CD147 has a role in tumor progression, is readily detectable in the circulation, and is abundantly expressed in hepatocellular carcinoma (HCC). Advanced HCC patients are a heterogeneous group with some individuals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d721f63515527b706824bc7c13810252
https://doi.org/10.1111/jgh.13148
https://doi.org/10.1111/jgh.13148
Autor:
Annette E. Maczurek, Magdalena A. Budzinska, Thomas Tu, Fiona J. Warner, Susan V. McLennan, A. Lee, Nicholas A. Shackel, S.R. Calabro
Publikováno v:
Journal of Gastroenterology and Hepatology. 30:1696-1704
Chronic liver disease causes significant morbidity and mortality through progressive fibrosis, cirrhosis, and liver cancer. The classical theory of fibrogenesis has hepatic stellate cells (HSCs) as the principal and only significant source of abnorma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68bf25ff1f4a767da22cac422a2edb27
https://doi.org/10.1111/jgh.13065
https://doi.org/10.1111/jgh.13065
Autor:
Alexandra F. Sharland, Thomas Tu, Jean Yee Hwa Yang, Fiona J. Warner, Geoffrey W. McCaughan, Wassim Rahman, D. Scott Bowden, Richard I. Christopherson, Alexander J. Thompson, Simone I. Strasser, David G. Bowen, Larissa Belov, Pauline Huang, Nicholas A. Shackel, David J. Koorey, Magdalena A. Budzinska, Jeremy S. Chrisp
Publikováno v:
Transplantation. 99:e120-e126
Hepatitis C virus (HCV) reinfection of the liver allograft after transplantation is universal, with some individuals suffering severe disease recurrence. Predictive markers of recurrent disease severity are urgently needed. In this study, we used a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df831128612e10c3239635b318610dd8
https://doi.org/10.1097/tp.0000000000000617
https://doi.org/10.1097/tp.0000000000000617
Autor:
Nicholas A. Shackel, Dennis K. Yue, Danqing Min, Fiona J. Warner, Wensheng Bao, Stephen M. Twigg, Susan V. McLennan
Publikováno v:
American Journal of Physiology-Cell Physiology. 299:C1212-C1219
CD147 is a highly glycosylated transmembrane protein that is known to play a role in regulation of many protein families. It has the unique ability to maintain functional activity in both the membrane bound state and in the soluble form. CD147 is kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfaa67c4e662933e160ddb2e952edbd
https://doi.org/10.1152/ajpcell.00228.2010
https://doi.org/10.1152/ajpcell.00228.2010
Autor:
Mélanie A. Eckersley-Maslin, Geoffrey W. McCaughan, Candice Alexandra Grzelak, Fiona J. Warner, Nicholas A. Shackel
Publikováno v:
Journal of Gastroenterology and Hepatology. 24:1608-1616
The contribution of bone marrow stem cell responses to liver homeostasis, injury and malignancy is discussed in this review. Pluripotent stem cells or their more committed progenitor progeny are essential to tissue development, regeneration and repai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ca414929d0e8f44c86bf771b600e87
https://doi.org/10.1111/j.1440-1746.2009.06004.x
https://doi.org/10.1111/j.1440-1746.2009.06004.x