High incidence of thromboembolism in patients with chronic GVHD: association with severity of GVHD and donor-recipient ABO blood group

Autor: Najla El Jurdi, Heba Elhusseini, Joan Beckman, Todd E. DeFor, Grigori Okoev, John Rogosheske, Aleksandr Lazaryan, Kristen Weiler, Veronika Bachanova, Brian C. Betts, Bruce R. Blazar, Claudio G. Brunstein, Fiona He, Shernan G. Holtan, Murali Janakiram, Radhika Gangaraju, Joseph Maakaron, Margaret L. MacMillan, Armin Rashidi, Erica D. Warlick, Smita Bhatia, Gregory Vercellotti, Daniel J. Weisdorf, Mukta Arora

Publikováno v: Blood Cancer Journal, Vol 11, Iss 5, Pp 1-7 (2021)

Key points Patients with chronic GVHD after allogeneic hematopoietic cell transplantation are at high risk for thromboembolic events occurring years after diagnosis. More severe chronic GVHD, non-O donor-recipient ABO compared to O-O match and person

Externí odkaz: https://doaj.org/article/271f0e7337a541dbb1020ddc785fbb6c

Association of CD34 Cell Dose with 5-Year Overall Survival after Peripheral Blood Allogeneic Hematopoietic Cell Transplantation in Adults with Hematologic Malignancies

Autor: Qing Cao, Najla El Jurdi, Daniel J. Weisdorf, Veronika Bachanova, Joseph Maakaron, Mukta Arora, Brian C. Betts, Erica D. Warlick, Shernan G. Holtan, Claudio G. Brunstein, Timothy D. Gauntner, Fiona He

Publikováno v: Transplantation and Cellular Therapy. 28:88-95

Background : Higher CD34 cell dose is associated with improved engraftment after peripheral blood allogeneic hematopoietic stem cell transplantation (alloHCT), but may also increase the risk of long-term complications, such as graft-versus-host disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a15ee84dee1fba0808f3e5408892e68
https://doi.org/10.1016/j.jtct.2021.11.004

Long-term safety for patients with tisagenlecleucel-treated relapsed/refractory diffuse large B-cell lymphoma

Autor: Ulrich Jaeger, Constantine S. Tam, Peter Borchmann, Joseph P. McGuirk, Marianne Johansen, Edmund K. Waller, Samantha Jaglowski, Charalambos Andreadis, Stephen R. Foley, Jason R. Westin, Isabelle Fleury, P. Joy Ho, Stephan Mielke, Takanori Teshima, Gilles Salles, Stephen J. Schuster, Fiona He, Richard T. Maziarz, Sebastian Mayer, Shinichi Makita, Marie J. Kersten, Monalisa Ghosh, Nina Wagner-Johnston, Koji Kato, Paolo Corradini, Hideki Goto, Silvia Colicino, Abhijit Agarwal, Chiara Lobetti-Bodoni, Michael R. Bishop

Publikováno v: Jaeger, U, Tam, C S, Borchmann, P, McGuirk, J P, Johansen, M, Waller, E K, Jaglowski, S, Andreadis, C, Foley, S R, Westin, J R, Fleury, I, Ho, P J, Mielke, S, Teshima, T, Salles, G, Schuster, S J, He, F, Maziarz, R T, Mayer, S, Makita, S, Kersten, M J, Ghosh, M, Wagner-Johnston, N, Kato, K, Corradini, P, Goto, H, Colicino, S, Agarwal, A, Lobetti-Bodoni, C & Bishop, M R 2022, ' Long-term safety for patients with tisagenlecleucel-treated relapsed/refractory diffuse large B-cell lymphoma ', Blood, vol. 6, no. 16, pp. 4816-4820 . https://doi.org/10.1182/bloodadvances.2021006193
Blood, 6(16), 4816-4820. American Society of Hematology
Blood advances, 6(16), 4816-4820. American Society of Hematology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845b49630d97668467f6c44f77f474ae
https://research.vumc.nl/en/publications/d4cb09d4-1d54-4e76-8613-106f26f29173

The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male mice

Autor: Mathieu Favier, Elena Martin Garcia, Romain Icick, Camille de Almeida, Joachim Jehl, Mazarine Desplanque, Johannes Zimmermann, Annabelle Henrion, Nina Mansouri-Guilani, Coline Mounier, Svethna Ribeiro, Fiona Henderson, Andrea Geoffroy, Sebastien Mella, Odile Poirel, Véronique Bernard, Véronique Fabre, Yulong Li, Christian Rosenmund, Stéphane Jamain, Florence Vorspan, Alexandre Mourot, Philibert Duriez, Leora Pinhas, Rafael Maldonado, Nicolas Pietrancosta, Stéphanie Daumas, Salah El Mestikawy

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Abstract Cholinergic striatal interneurons (ChIs) express the vesicular glutamate transporter 3 (VGLUT3) which allows them to regulate the striatal network with glutamate and acetylcholine (ACh). In addition, VGLUT3-dependent glutamate increases ACh

Externí odkaz: https://doaj.org/article/92f0421dd9334d49b5771f81a762f0c7

TP53 Altered Acute Myeloid Leukemia Stem Cells Hyperactivate Nuclear Factor-Kappa B

Autor: Marie Lue Antony, Klara E Noble-Orcutt, Jeffrey Lee Jensen, Fiona He, Zohar Sachs

Publikováno v: Blood. 140:3399-3400

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b15f9ea5b4ca3b387c98b06bc50c98e
https://doi.org/10.1182/blood-2022-170479