Výsledky vyhledávání - "Fiona Garner"

Akademický článek

Biological Monitoring: Evidence for Reductions in Occupational Exposure and Risk

Autor: Jackie Morton, Craig Sams, Elizabeth Leese, Fiona Garner, Shahwaiz Iqbal, Kate Jones

Publikováno v: Frontiers in Toxicology, Vol 4 (2022)

Aims: The aim of this publication is to explore occupational exposure trends from biological monitoring data collected over a period of more than 20 years. The data is stored within the HSE database, which holds more than 950,000 results from 120,000

Externí odkaz: https://doaj.org/article/68081c2cc130479ebf21a85c559a3bfc

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Supplementary Table from Elacestrant (RAD1901), a Selective Estrogen Receptor Degrader (SERD), Has Antitumor Activity in Multiple ER+ Breast Cancer Patient-derived Xenograft Models

Autor: Fiona Garner, Gary Hattersley, Dinesh M. Purandare, Jeffrey L. Brown, Hai Jiang, Nianjun Tao, Heike Arlt, Hitisha K. Patel, Teeru Bihani

Supplementary Table

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fccab120142b849f2163b795a443272
https://doi.org/10.1158/1078-0432.22462364

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Supplementary Figures from Elacestrant (RAD1901), a Selective Estrogen Receptor Degrader (SERD), Has Antitumor Activity in Multiple ER+ Breast Cancer Patient-derived Xenograft Models

Autor: Fiona Garner, Gary Hattersley, Dinesh M. Purandare, Jeffrey L. Brown, Hai Jiang, Nianjun Tao, Heike Arlt, Hitisha K. Patel, Teeru Bihani

Supplementary Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0affc5e557f62615a9ed3d3a8ee7f2
https://doi.org/10.1158/1078-0432.22462370

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Data from Elacestrant (RAD1901), a Selective Estrogen Receptor Degrader (SERD), Has Antitumor Activity in Multiple ER+ Breast Cancer Patient-derived Xenograft Models

Autor: Fiona Garner, Gary Hattersley, Dinesh M. Purandare, Jeffrey L. Brown, Hai Jiang, Nianjun Tao, Heike Arlt, Hitisha K. Patel, Teeru Bihani

Purpose: Estrogen receptor–positive (ER+) breast cancers are typically treated with endocrine agents, and dependence on the ER pathway is often retained even after multiple rounds of antiestrogen therapy. Selective estrogen receptor degraders (SERD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff3c157a1016b23c8bad8c1454b7e71
https://doi.org/10.1158/1078-0432.c.6525089

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Sargramostim and immune checkpoint inhibitors: combinatorial therapeutic studies in metastatic melanoma

Autor: Ahmad A. Tarhini, Fiona Garner, Ila Joshi

Publikováno v: Immunotherapy. 13:1011-1029

The use of immune checkpoint inhibitors in patients with metastatic melanoma generates clinical benefit, including improved survival. Yet disease resistance and immune-related adverse events persist as unmet needs. Sargramostim, a yeast-derived recom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1facfa2f8a2a14b126fb315648f3144a
https://doi.org/10.2217/imt-2021-0119

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Inhaled Sargramostim (Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor) for COVID-19-Associated Acute Hypoxemia: Results of the Phase 2, Randomized, Open-Label Trial (iLeukPulm)

Autor: Robert Paine, Robert Chasse, E Scott Halstead, Jay Nfonoyim, David J Park, Timothy Byun, Bela Patel, Guido Molina-Pallete, Estelle S Harris, Fiona Garner, Lorinda Simms, Sanjeev Ahuja, John L McManus, Debasish F Roychowdhury

Publikováno v: Military medicine.

Introduction Granulocyte-macrophage colony-stimulating factor (GM-CSF), a protein produced in the lung, is essential for pulmonary host defense and alveolar integrity. Prior studies suggest potential benefits in several pulmonary conditions, includin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382fbf3572ec75a094795cf132a8af44
https://pubmed.ncbi.nlm.nih.gov/36458916

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34 Monitoring with a Purpose: Using Biological Monitoring as Evidence for Reductions in Exposure and Risk

Autor: Kate Jones, Craig Sams, Jackie Morton, Liz Leese, Fiona Garner, Laura Kenny, Shahwaiz Iqbal

Publikováno v: Annals of Work Exposures and Health. 67:i21-i21

HSE operates the leading UK laboratory for biological monitoring. Samples come via HSE’s inspectors, hygienists and external occupational health professionals. Since 1996 all results have been stored in a database that now has over 950,000 results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ac789590c9a7d472a50f76682215a91
https://doi.org/10.1093/annweh/wxac087.054

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Elacestrant (RAD1901), a Selective Estrogen Receptor Degrader (SERD), Has Antitumor Activity in Multiple ER

Autor: Teeru, Bihani, Hitisha K, Patel, Heike, Arlt, Nianjun, Tao, Hai, Jiang, Jeffrey L, Brown, Dinesh M, Purandare, Gary, Hattersley, Fiona, Garner

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 23(16)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6caabc9273e43fc1e40585710005e08f
https://pubmed.ncbi.nlm.nih.gov/28473534

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A Phase 2 Study of Cpi-0610, a Bromodomain and Extraterminal (BET) Inhibitor, in Patients with Myelofibrosis (MF)

Autor: Fiona Garner, Marina Kremyanskaya, John Mascarenhas, Jennifer A. Mertz, Srdan Verstovsek, Adrian M. Senderowicz, Ronald Hoffman

Publikováno v: Blood. 132:5481-5481

MF is a myeloproliferative neoplasm characterized by abnormal megakaryocytes and elevated proinflammatory cytokines which results in bone marrow fibrosis, progressive hepatosplenomegaly due to extramedullary hematopoiesis, and debilitating constituti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4093f272d6e4f00e29075e1e1255ef4f
https://doi.org/10.1182/blood-2018-99-119157

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