Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fiona G. Mackinnon"'
Autor:
Andrew D. Cox, Derek W. Hood, James C. Richards, Ronald Chalmers, Christoph M. Tang, Joyce S. Plested, Fiona G. Mackinnon, E. Richard Moxon, Katherine Makepeace, Philip A. Coull, J. Claire Wright
Publikováno v:
Molecular Microbiology. 43:931-943
We have identified a gene, lpt-3, that is required for the addition of phosphoethanolamine to the 3-position (PEtn-3) on the beta-chain heptose (HepII) of the inner core lipopolysaccharide (LPS) of Neisseria meningitidis (Nm). The presence of this PE
Autor:
Helen G Griffiths, A. K. Lehmann, Berne Ferry, Katherine Makepeace, James C. Richards, Joyce S. Plested, E. Richard Moxon, Philip A. Coull, Mark Herbert, Fiona G. Mackinnon
Publikováno v:
Infection and Immunity. 69:3203-3213
A recently described flow cytometric opsonophagocytic assay (OPA) was adapted to quantify the functional activity of serum antibodies specifically directed against serogroup B inner core lipopolysaccharide (LPS) ofNeisseria meningitidis. The percenta
Autor:
Andrew Robinson, Andrew Gorringe, Fiona G. Mackinnon, Andrew J. Fox, Alison S. Johnson, Ray Borrow
Publikováno v:
FEMS Immunology & Medical Microbiology. 25:349-354
An effective vaccine for serogroup B meningococci has yet to be developed and attention has turned to subcapsular antigens of the meningococcus as possible vaccine candidates. Iron binding proteins are being studied, with most interest focused on the
Autor:
Milan S. Blake, Fiona G. Mackinnon, Mohammed H. Sayegh, Yu Ho, Francis Michon, Anil Chandraker, Lee M. Wetzler
Publikováno v:
The Journal of Infectious Diseases. 180:755-761
A T cell-dependent immune response to group C meningococcal capsular polysaccharide (CPS) can be elicited when CPS is conjugated to the class 3 neisserial porin (CPS-porin). Treatment of CPS-porin-immunized mice with B7-2 blocking monoclonal antibody
Publikováno v:
Microbial Pathogenesis. 15:359-366
Using an infant mouse intranasal infection model, we have compared the virulence of 17 epidemiologically related isolates of Neisseria meningitidis associated with an outbreak of meningococcal disease in Gloucestershire, UK, and one German isolate. T
Autor:
Fiona G Mackinnon
Publikováno v:
Australian Prescriber. 35:197-197
Publikováno v:
Microbial pathogenesis. 12(6)
In human meningococcal infection the mechanism of the transition from asymptomatic carriage to invasive disease is unknown, partly due to the lack of an effective animal model that mimics all stages of the human disease. Therefore, we have endeavoure