Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Fiona Furlong"'
Autor:
Yinghui Ren, Limin Cao, Limin Wang, Sijia Zheng, Qicheng Zhang, Xueru Guo, Xueqin Li, Mengmeng Chen, Xiang Wu, Fiona Furlong, Zhaowei Meng, Ke Xu
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract Tumor progression requires the communication between tumor cells and tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) are major components of stromal cells. CAFs contribute to metastasis process through direct or indirect i
Externí odkaz:
https://doaj.org/article/0188e3f77de34756b027cce3d93a57a2
Autor:
Lana McClements, Stephanie Annett, Anita Yakkundi, Martin O’Rourke, Andrea Valentine, Nermeen Moustafa, Abdelrahim Alqudah, Bruno M. Simões, Fiona Furlong, Amy Short, Stuart A. McIntosh, Helen O. McCarthy, Robert B. Clarke, Tracy Robson
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Optimising breast cancer treatment remains a challenge. Resistance to therapy is a major problem in both ER- and ER+ breast cancer. Tumour recurrence after chemotherapy and/or targeted therapy leads to more aggressive tumours with
Externí odkaz:
https://doaj.org/article/2e02e553d486425d82cd0912d627c29b
Autor:
Heba Abd-El-Azim, Ismaiel A. Tekko, Ahlam Ali, Alyaa Ramadan, Noha Nafee, Nawal Khalafallah, Taifur Rahman, William Mcdaid, Rania G. Aly, Lalitkumar K. Vora, Steven J. Bell, Fiona Furlong, Helen O. McCarthy, Ryan F. Donnelly
Publikováno v:
Abd-El-Azim, H, Tekko, I A, Ali, A, Ramadan, A, Nafee, N, Khalafallah, N, Rahman, T, Mcdaid, W, Aly, R G, Vora, L K, Bell, S J, Furlong, F, McCarthy, H O & Donnelly, R F 2022, ' Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer ', Journal of controlled release : official journal of the Controlled Release Society, vol. 348, pp. 849-869 . https://doi.org/10.1016/j.jconrel.2022.06.027
Photodynamic therapy (PDT) to manage non-melanoma skin cancers has garnered great attention over the past few years. Hypericin (Hy) is a potent lipid-soluble photosensitiser with promising anticancer therapeutic activities. Nevertheless, its poor wat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc4e360d4c150364d4ebce92428fe42
https://pure.qub.ac.uk/en/publications/18cc4767-8666-4e11-8fdd-5576ba39cf17
https://pure.qub.ac.uk/en/publications/18cc4767-8666-4e11-8fdd-5576ba39cf17
Autor:
Limin Cao, Xueru Guo, Fiona Furlong, Zhaowei Meng, Xiang Wu, Mengmeng Chen, Sijia Zheng, Qicheng Zhang, Limin Wang, Yinghui Ren, Ke Xu, Xueqin Li
Publikováno v:
Ren, Y, Cao, L, Wang, L, Zheng, S, Zhang, Q, Guo, X, Li, X, Chen, M, Wu, X, Furlong, F, Meng, Z & Xu, K 2021, ' Autophagic secretion of HMGB1 from cancer-associated fibroblasts promotes metastatic potential of non-small cell lung cancer cells via NFκB signaling ', Cell, Death & Disease, vol. 12, no. 10, 858 . https://doi.org/10.1038/s41419-021-04150-4
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Tumor progression requires the communication between tumor cells and tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) are major components of stromal cells. CAFs contribute to metastasis process through direct or indirect interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fb675a62fc7319cf70c9b1e0fabc7c
https://pure.qub.ac.uk/en/publications/autophagic-secretion-of-hmgb1-from-cancerassociated-fibroblasts-promotes-metastatic-potential-of-nonsmall-cell-lung-cancer-cells-via-nfb-signaling(e4963f16-24bf-43fc-85ca-a900034e8d2e).html
https://pure.qub.ac.uk/en/publications/autophagic-secretion-of-hmgb1-from-cancerassociated-fibroblasts-promotes-metastatic-potential-of-nonsmall-cell-lung-cancer-cells-via-nfb-signaling(e4963f16-24bf-43fc-85ca-a900034e8d2e).html
Autor:
Adrien Kissenpfennig, Irina G. Tikhonova, Shaun Spence, Clive Drakeford, Amy Short, Stephanie Annett, Pauline Johnson, Ciaran Campbell, Carolina Denis Garciarena, Danny Sharpe, Jennifer Dowling, Margaret Dennehy, Anita Yakkundi, Steve Kerrigan, Gianpiero L. Cavalleri, Fiona Furlong, Jacqueline C.Y. Lai, Tracy Robson, James O'Donnell, Gillian Moore
Publikováno v:
SSRN Electronic Journal.
A breakdown in vascular integrity and excessive inflammation are hallmarks of serious pathological conditions including sepsis, acute respiratory distress syndrome (ARDs) and most recently, severe COVID-19. FK506 – binding protein like (FKBPL) is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e957afae6fcc54722564da8ff0ed54
https://doi.org/10.2139/ssrn.3858052
https://doi.org/10.2139/ssrn.3858052
Autor:
Caitlin Beggan, Aaron Maguire, Tara Byrne, Sharon O'Toole, Amanda McCann, Stephen Bridgett, Karolina Weiner-Gorzel, Patricia Fitzpatrick, Fiona Furlong, Fengyu Zhang, Ahlam A. Ali, John J. O'Leary
Publikováno v:
Ali, A, Zhang, F, Maguire, A, Byrne, T, Weiner-Gorzel, K, Bridgett, S, O’toole, S, O’leary, J, Beggan, C, Fitzpatrick, P, McCann, A & Furlong, F 2020, ' Hdac6 degradation inhibits the growth of high-grade serous ovarian cancer cells ', Cancers, vol. 12, no. 12, 3734 . https://doi.org/10.3390/cancers12123734
Cancers
Cancers, Vol 12, Iss 3734, p 3734 (2020)
Volume 12
Issue 12
Cancers
Cancers, Vol 12, Iss 3734, p 3734 (2020)
Volume 12
Issue 12
Histone deacetylase 6 (HDAC6) is a unique histone deacetylating enzyme that resides in the cell cytoplasm and is linked to the modulation of several key cancer related responses, including cell proliferation and migration. The promising anti-cancer r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe021d2e141e84eedfdb40b20d0e26a1
https://pure.qub.ac.uk/en/publications/d32a0f96-1e53-4ab1-b2cf-89e44d3da13e
https://pure.qub.ac.uk/en/publications/d32a0f96-1e53-4ab1-b2cf-89e44d3da13e
Autor:
Catherine J. Kennedy, Amy Short, Ian Harley, Tracy Robson, W. Glenn McCluggage, Mark Bates, Anna deFazio, Fiona Furlong, Anita Yakkundi, Helen O. McCarthy, Cian M. McCrudden, John J. O'Leary, Donal J. Brennan, Gillian Moore, Nermeen Moustafa, Laura Nelson, Sharon O'Toole, Sudipto Das, Lana McClements, Stephanie Annett, Alison Brand, Darran P. O'Connor, Adrien Kissenpfennig, Raghwa Sharma, Andrea Marshall, Ciaran O'Riain
Publikováno v:
Annett, S, Moore, G, Short, A, Marshall, A, McCrudden, C, Yakkundi, A, Das, S, McCluggage, W G, Nelson, L, Harley, I, Moustafa, N, Kennedy, C J, deFazio, A, Brand, A, Sharma, R, Brennan, D, O'Toole, S, O'Leary, J, Bates, M, O'Riain, C, O'Connor, D, Furlong, F, McCarthy, H, Kissenpfennig, A, McClements, L & Robson, T 2020, ' FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer ', British Journal of Cancer, vol. 2020, no. 126, pp. 361 . https://doi.org/10.1038/s41416-019-0649-5
British Journal of Cancer
British Journal of Cancer
Background ALM201 is a therapeutic peptide derived from FKBPL that has previously undergone preclinical and clinical development for oncology indications and has completed a Phase 1a clinical trial in ovarian cancer patients and other advanced solid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5cfaa907dbcf4bc7183b58d1c0c388
https://hdl.handle.net/10453/137191
https://hdl.handle.net/10453/137191
Autor:
Tara Byrne, Laura Nelson, James P Beirne, Tracy Robson, W. Glenn McCluggage, Jennifer E. Quinn, Fiona Furlong, Daniel J. Sharpe
Publikováno v:
Byrne, T, Nelson, L, Beirne, J, Sharpe, D, Quinn, J E, Glenn McCluggage, W, Robson, T & Furlong, F 2018, ' BRCA1 and MAD2 are Co-expressed and are Prognostic Indicators in Tubo-ovarian High-grade Serous Carcinoma ', International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, vol. 28, no. 3, pp. 472-478 . https://doi.org/10.1097/IGC.0000000000001214
ObjectivesThe aim of this study was to investigate the relationship between BRCA1 and mitotic arrest deficiency protein 2 (MAD2) protein expression, as determined by immunohistochemistry, and clinical outcomes in epithelial ovarian carcinoma (EOC).Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5249daebd9b343745cb24325b4e9c6d
https://doi.org/10.1097/igc.0000000000001214
https://doi.org/10.1097/igc.0000000000001214
Autor:
Sonja Suvakov, Naomi Todd, Alyson Hunter, Ahlam A. Ali, Kelly-Ann Eastwood, Ian S. Young, David R. McCance, Guillermo Lopez-Campos, Valerie Holmes, Lana McClements, Vesna D. Garovic, Claire Richards, Abdelrahim Alqudah, Fiona Furlong, Anna Krasnodembskaya
Publikováno v:
Journal of Hypertension. 39:e26-e27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0200b0323e36c4b69bcadc65ff8945c
https://doi.org/10.1097/01.hjh.0000744632.79980.c9
https://doi.org/10.1097/01.hjh.0000744632.79980.c9
Autor:
Wafa' T Al-Jamal, Jani Seitsonen, Ahlam A. Ali, Amalia Ruiz, Fiona Furlong, Janne Ruokolainen, Vera L Silva, Jonathan A. Coulter, Sara Pereira
Publikováno v:
Silva, V L, Ruiz, A, Ali, A, Pereira, S, Seitsonen, J, Ruokolainen, J, Furlong, F, Coulter, J & Al-Jamal, W T 2021, ' Hypoxia-targeted cupric-tirapazamine liposomes potentiate radiotherapy in prostate cancer spheroids ', International journal of pharmaceutics, vol. 607, 121018 . https://doi.org/10.1016/j.ijpharm.2021.121018
Funding Information: V.L.S is grateful for her PhD studentship awarded by the University of East Anglia (studentship ref. 100099479). This work was also supported by the Prostate Cancer UK (CDF-12-002 Fellowship), the Engineering and Physical Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d10f817546d425881a28937c33e35c
https://doi.org/10.1016/j.ijpharm.2021.121018
https://doi.org/10.1016/j.ijpharm.2021.121018