Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fiona Eyers"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163392 (2016)
Exacerbations of asthma are linked to significant decline in lung function and are often poorly controlled by corticosteroid treatment. Clinical investigations indicate that viral and bacterial infections play crucial roles in the onset of steroid-re
Externí odkaz:
https://doaj.org/article/11ecff0b2fe14f7d81ffc22ac6fb05fb
Autor:
Maximilian W Plank, Steven Maltby, Hock L Tay, Jessica Stewart, Fiona Eyers, Philip M Hansbro, Paul S Foster
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144810 (2015)
MicroRNAs are post-transcriptional regulators of gene expression that are differentially regulated during development and in inflammatory diseases. A role for miRNAs in allergic asthma is emerging and further investigation is required to determine wh
Externí odkaz:
https://doaj.org/article/78686957c1254903a706059d07dd7d36
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97537 (2014)
BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNAs that regulate complex transcriptional networks underpin immune responses. However, little is known about the specific miRNA networks that control differentiation of specific leukocyte subsets.
Externí odkaz:
https://doaj.org/article/d7b6f01be829458fb16fd31f0752b678
Identification of microRNAs regulating the developmental pathways of bone marrow derived mast cells.
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98139 (2014)
MicroRNAs (miRNAs) play important roles in leukocyte differentiation, although those utilised for specific programs and key functions remain incompletely characterised. As a global approach to gain insights into the potential regulatory role of miRNA
Externí odkaz:
https://doaj.org/article/11397c5503b944baae9f2a658bbf3d3c
Autor:
Leon A. Sokulsky, Simon Keely, Philip G. Board, Paul S. Foster, Ming Yang, Simonne Sherwin, Gerard E. Kaiko, Fiona Eyers, Bridie J. Goggins
Publikováno v:
Clinical & Experimental Allergy. 50:609-624
BACKGROUND Glutathione S-transferases omega class 1 (GSTO1-1) is a unique member of the GST family regulating cellular redox metabolism and innate immunity through the promotion of LPS/TLR4/NLRP3 signalling in macrophages. House dust mite (HDM) trigg
Autor:
Ming Yang, Karen L. Laurie, Ian G. Barr, Keilah Garcia Netto, Xiang Li, Xiaoming Liu, Fiona Eyers, Hock L. Tay, Paul S. Foster, Thi Hiep Nguyen, Alan Chen-Yu Hsu, Chi Liu, Leon A. Sokulsky
Publikováno v:
Respirology (Carlton, Vic.)REFERENCES. 26(11)
BACKGROUND AND OBJECTIVE Influenza virus (FLU), rhinovirus (RV) and respiratory syncytial virus (RSV) are the most common acute respiratory infections worldwide. Infection can cause severe health outcomes, while therapeutic options are limited, prima
Publikováno v:
Allergy and immunology.
Publikováno v:
Allergy and immunology.
Viral respiratory infections trigger exacerbation of asthma, characterized by an exaggerated inflammatory response and airway hyperresponsiveness (AHR) resulting in worsening disease symptoms and a decline in lung function. Conventional therapies suc
Autor:
Paul S. Foster, Jodie L. Simpson, Ming Yang, Fiona Eyers, Steven Maltby, Thi Hiep Nguyen, Peter G. Gibson, Katherine J. Baines
Publikováno v:
The Journal of Immunology. 196:3547-3558
Viral respiratory infections trigger severe exacerbations of asthma, worsen disease symptoms, and impair lung function. To investigate the mechanisms underlying viral exacerbation, we established a mouse model of respiratory syncytial virus (RSV)–i
Publikováno v:
The Journal of Immunology. 196:3421-3428
MicroRNAs (miRNAs) are short noncoding RNAs that regulate a broad spectrum of biological processes, including immune responses. Although the contributions of miRNAs to the function of immune cells are beginning to emerge, their specific roles remain