Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Fiona E. Yull"'
Autor:
Evan B. Glass, Alyssa A. Hoover, Kennady K. Bullock, Matthew Z. Madden, Bradley I. Reinfeld, Whitney Harris, Dominique Parker, Demetra H. Hufnagel, Marta A. Crispens, Dineo Khabele, W. Kimryn Rathmell, Jeffrey C. Rathmell, Andrew J. Wilson, Todd D. Giorgio, Fiona E. Yull
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background Current cancer immunotherapies have made tremendous impacts but generally lack high response rates, especially in ovarian cancer. New therapies are needed to provide increased benefits. One understudied approach is to target the l
Externí odkaz:
https://doaj.org/article/695878c019a54c44a19092e66e5e5079
Autor:
Alyssa A. Hoover, Demetra H. Hufnagel, Whitney Harris, Kennady Bullock, Evan B. Glass, Esther Liu, Whitney Barham, Marta A. Crispens, Dineo Khabele, Todd D. Giorgio, Andrew J. Wilson, Fiona E. Yull
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs from M2 (pro-tumor) to M1 (anti-tumor) phenotypes represents an important
Externí odkaz:
https://doaj.org/article/1721307f4b964b83b11c876f207a8f61
Autor:
Demetra H. Hufnagel, Andrew J. Wilson, Jamie Saxon, Timothy S. Blackwell, Jaclyn Watkins, Dineo Khabele, Marta A. Crispens, Fiona E. Yull, Alicia Beeghly-Fadiel
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background The canonical and non-canonical nuclear factor-kappaB (NF-κB) signaling pathways have key roles in cancer, but studies have previously evaluated only the association of canonical transcription factors and ovarian cancer survival.
Externí odkaz:
https://doaj.org/article/64b228fc34df4340b790ce58498187c7
Autor:
Evan B. Glass, Shirin Masjedi, Stephanie O. Dudzinski, Andrew J. Wilson, Craig L. Duvall, Fiona E. Yull, Todd D. Giorgio
Publikováno v:
ACS Omega, Vol 4, Iss 16, Pp 16756-16767 (2019)
Externí odkaz:
https://doaj.org/article/707777e550c74bc5b73e57113c426b70
Autor:
Allyson G. McLoed, Taylor P. Sherrill, Dong-Sheng Cheng, Wei Han, Jamie A. Saxon, Linda A. Gleaves, Pingsheng Wu, Vasiliy V. Polosukhin, Michael Karin, Fiona E. Yull, Georgios T. Stathopoulos, Vassilis Georgoulias, Rinat Zaynagetdinov, Timothy S. Blackwell
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 120-132 (2016)
Although epithelial NF-κB signaling is important for lung carcinogenesis, NF-κB inhibitors are ineffective for cancer treatment. To explain this paradox, we studied mice with genetic deletion of IKKβ in myeloid cells and found enhanced tumorigenes
Externí odkaz:
https://doaj.org/article/f58ff440a1344da388aafc8cddd5f332
Autor:
Andrea A. Hill, Emily K. Anderson-Baucum, Arion J. Kennedy, Corey D. Webb, Fiona E. Yull, Alyssa H. Hasty
Publikováno v:
Molecular Metabolism, Vol 4, Iss 10, Pp 665-677 (2015)
Objective: Macrophage accumulation in adipose tissue (AT) during obesity contributes to inflammation and insulin resistance. Recruitment of monocytes to obese AT has been the most studied mechanism explaining this accumulation. However, recent eviden
Externí odkaz:
https://doaj.org/article/495cf572ae5149b79793fd4e85ae6883
Autor:
Hui Li, Wei Han, Vasilly Polosukhin, Fiona E. Yull, Brahm H. Segal, Can-Mao Xie, Timothy S. Blackwell
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Introduction. Since the NF-κB pathway regulates both inflammation and host defense, it is uncertain whether interventions targeting NF-κB would be beneficial in sepsis. Based on the kinetics of the innate immune response, we postulated that selecti
Externí odkaz:
https://doaj.org/article/4450ed477dc5413aa19175d0e8f955df
Autor:
Georgios T. Stathopoulos, Antonia Marazioti, Manolis Pasparakis, Timothy S. Blackwell, Fiona E. Yull, Sebastian Marwitz, Torsten Goldmann, Vasileios Armenis, Theodora Agalioti, Magda Spella, Nikolaos I. Kanellakis, Ioanna Giopanou, Marina Lianou, Georgia A. Giotopoulou, Maria Papageorgopoulou, Ioannis Lilis, Malamati Vreka
Supplementary file containing Supplementary Methods (pertaining to reagents, imaging, immunoblotting, cellular studies, microarray data, NF-κB ELISA, PCR, cell culture, histology, cytology, flow cytometry, constructs, and cellular Assays), 4 Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f118144bdeeb859bccc720a623362b2
https://doi.org/10.1158/0008-5472.22417056
https://doi.org/10.1158/0008-5472.22417056
Autor:
Georgios T. Stathopoulos, Antonia Marazioti, Manolis Pasparakis, Timothy S. Blackwell, Fiona E. Yull, Sebastian Marwitz, Torsten Goldmann, Vasileios Armenis, Theodora Agalioti, Magda Spella, Nikolaos I. Kanellakis, Ioanna Giopanou, Marina Lianou, Georgia A. Giotopoulou, Maria Papageorgopoulou, Ioannis Lilis, Malamati Vreka
Although oncogenic activation of NFκB has been identified in various tumors, the NFκB–activating kinases (inhibitor of NFκB kinases, IKK) responsible for this are elusive. In this study, we determined the role of IKKα and IKKβ in KRAS-mutant l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bea61fccec74be0be06b24dc38c02c
https://doi.org/10.1158/0008-5472.c.6509730.v1
https://doi.org/10.1158/0008-5472.c.6509730.v1
Autor:
Ann Richmond, Fiona E. Yull, Michael Karin, Sebastian Joyce, Gregory D. Ayers, Mark Boothby, Pavlo Gilchuk, Whitney Barham, Oriana E. Hawkins, Jinming Yang
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fc2d65220e4b30ef6e7a599cbec87f
https://doi.org/10.1158/0008-5472.22403763.v1
https://doi.org/10.1158/0008-5472.22403763.v1