Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Fiona E. Watt"'
Autor:
Jackie L. Whittaker, Raneem Kalsoum, James Bilzon, Philip G. Conaghan, Kay Crossley, George R. Dodge, Alan Getgood, Xiaojuan Li, Elena Losina, Deborah J. Mason, Brian Pietrosimone, May Arna Risberg, Frank Roemer, David Felson, Adam G. Culvenor, Duncan Meuffels, Nicole Gerwin, Lee S. Simon, L. Stefan Lohmander, Martin Englund, Fiona E. Watt
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 2, Pp 100449- (2024)
Objective: The global impact of osteoarthritis is growing. Currently no disease modifying osteoarthritis drugs/therapies exist, increasing the need for preventative strategies. Knee injuries have a high prevalence, distinct onset, and strong independ
Externí odkaz:
https://doaj.org/article/9634a8b393d041f6a76e083f95c7d6d1
Autor:
Malvika Gulati, Gretchen Brewer, Andrew Judge, Donna Kennedy, Tonia L. Vincent, Fiona E. Watt
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
IntroductionHand osteoarthritis is more common in women, and its risk increases around the time of the menopause. We set out to describe the timing between menopause and the onset of symptomatic hand osteoarthritis (OA), and associations with the use
Externí odkaz:
https://doaj.org/article/9a161359493c49fc817444e0919d59b4
Autor:
Ioana R. Marian, Megan Goff, Jennifer A. E. Williams, Malvika Gulati, Mae Chester-Jones, Anne Francis, Marion Watson, Tonia L. Vincent, Sue Woollacott, Charles Mackworth-Young, Victoria Glover, Dominic Furniss, Matthew Gardiner, Sarah E. Lamb, Katy Vincent, Vicki S. Barber, Joanna Black, Susan J. Dutton, Fiona E. Watt
Publikováno v:
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Background Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher amongst women, particularly around the age of the menopause. Whilst the relationship between sex hormones and
Externí odkaz:
https://doaj.org/article/814a33c795b04098be6e8c16fca98923
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The bone marrow (BM) vascular niche microenvironments harbor stem and progenitor cells of various lineages. Bone angiogenesis is distinct and involves tissue-specific signals. The nurturing vascular niches in the BM are complex and heterogenous consi
Externí odkaz:
https://doaj.org/article/10e86fe20d5f4cbcb98674e2e2a5cd1d
Autor:
Claire Mennan, Timothy Hopkins, Alastair Channon, Mark Elliott, Brian Johnstone, Timor Kadir, John Loughlin, Mandy Peffers, Andrew Pitsillides, Nidhi Sofat, Caroline Stewart, Fiona E. Watt, Eleftheria Zeggini, Cathy Holt, Sally Roberts
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 3, Pp 100081- (2020)
Objective: This UK-wide OATech Network + consensus study utilised a Delphi approach to discern levels of awareness across an expert panel regarding the role of existing and novel technologies in osteoarthritis research. To direct future cross-discipl
Externí odkaz:
https://doaj.org/article/0f8e9e91f8d64297b2f2880080ad00ea
Autor:
Mylène P. Jansen, Simon C. Mastbergen, Fiona E. Watt, Elske J. Willemse, Tonia L. Vincent, Sander Spruijt, Pieter J. Emans, Roel J. H. Custers, Ronald J. van Heerwaarden, Floris P. J. G. Lafeber
Publikováno v:
Applied Sciences, Vol 11, Iss 15, p 7156 (2021)
Knee joint distraction (KJD) treatment has shown cartilage repair and clinical improvement in patients with osteoarthritis, as has high tibial osteotomy (HTO). Following KJD, TGFβ-1 and IL-6 were increased in synovial fluid (SF), factors related to
Externí odkaz:
https://doaj.org/article/cc4ebbe54d454d81993771f6657477ad
Autor:
Fiona E. Watt, Malvika Gulati
Publikováno v:
European Medical Journal, Vol 2, Iss 1, Pp 50-58 (2017)
Osteoarthritis (OA) is the most common form of arthritis, yet has historically lagged far behind rheumatoid arthritis in terms of drug development. Despite the many challenges presented by clinical trials in OA, improvements in our understanding of d
Externí odkaz:
https://doaj.org/article/48e12f09b9664d5eaf81d0c5d382649a
Autor:
Zoe Paskins, Clare E Farmer, Fay Manning, David A Andersson, Tim Barlow, Felicity L Bishop, Christopher A Brown, Amanda Clark, Emma M Clark, Debra Dulake, Malvika Gulati, Christine L Le Maitre, Richard K Jones, John Loughlin, Deborah J Mason, Maura McCarron, Neil L Millar, Hemant Pandit, George Peat, Stephen M Richardson, Emma J Salt, E Jane Taylor, Linda Troeberg, Ruth K Wilcox, Elspeth Wise, Colin Wilkinson, Fiona E Watt
Publikováno v:
The Lancet Rheumatology
Richardson, S M 2022, ' Research priorities to reduce the impact of musculoskeletal disorders: a priority setting exercise with the child health and nutrition research initiative method ', The Lancet Rheumatology, vol. 4, no. 9, pp. e635-e645 . https://doi.org/10.1016/S2665-9913(22)00136-9
e645
e635
Richardson, S M 2022, ' Research priorities to reduce the impact of musculoskeletal disorders: a priority setting exercise with the child health and nutrition research initiative method ', The Lancet Rheumatology, vol. 4, no. 9, pp. e635-e645 . https://doi.org/10.1016/S2665-9913(22)00136-9
e645
e635
Involving research users in setting priorities for research is essential to ensure the outcomes are patient-centred and\ud maximise its value and impact. The Musculoskeletal Disorders Research Advisory Group Versus Arthritis led a\ud research priorit
Autor:
Linyi, Zhu, Pragash, Kamalathevan, Lada A, Koneva, Jadwiga Miotla, Zarebska, Anastasios, Chanalaris, Heba, Ismail, Akira, Wiberg, Michael, Ng, Hayat, Muhammad, John, Walsby-Tickle, James S O, McCullagh, Fiona E, Watt, Stephen N, Sansom, Dominic, Furniss, Matthew D, Gardiner, Tonia L, Vincent, Nick, Riley, Michelle, Spiteri, Ian, McNab, Christopher, Little, Lucy, Cogswell, Paul, Critchley, Henk, Giele, Rebecca, Shirley
Publikováno v:
Science translational medicine. 14(676)
More than 40% of individuals will develop osteoarthritis (OA) during their lifetime, yet there are currently no licensed disease-modifying treatments for this disabling condition. Common polymorphic variants in