Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Fiona E. Pryde"'
Autor:
Ann-Marie Ritchie, David W. Melton, Jim Selfridge, Denis Jullien, Shirin Khalili, Kathryn Robertson, Fiona E. Pryde, Yasuhisa Adachi
Publikováno v:
Journal of Cell Science. 118:2043-2055
53BP1 protein is re-localized to the sites of DNA damage after ionizing radiation (IR) and is involved in DNA-damage-checkpoint signal transduction. We examined the dynamics of GFP-53BP1 in living cells. The protein starts to accumulate at the sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d15e3d740dd3f6c2b00ac4ccab1259
https://doi.org/10.1242/jcs.02336
https://doi.org/10.1242/jcs.02336
Autor:
Edward J. Louis, Fiona E. Pryde
Publikováno v:
The EMBO Journal. 18:2538-2550
Silencing at native yeast telomeres, in which the subtelomeric elements are intact, is different from silencing at terminal truncations. The repression of URA3 inserted in different subtelomeric positions at several chromosome ends was investigated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6386f9d0e7fcd1c5bac10b31b8c92e
https://doi.org/10.1093/emboj/18.9.2538
https://doi.org/10.1093/emboj/18.9.2538
Autor:
Sophie G. Martin, Susan M. Gasser, Fiona E. Pryde, Hazel Gorham, Thierry Laroche, Monica Gotta, Edward J. Louis
Publikováno v:
Current Biology. 8(11):653-657
The mammalian Ku70 and Ku86 proteins form a heterodimer that binds to the ends of double-stranded DNA in vitro and is required for repair of radiation-induced strand breaks and V(D)J recombination [1,2]. Deletion of the Saccharomyces cerevisiae genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642fe4bcfaf1aca5735aca41d61d21a4
Publikováno v:
Yeast. 11:371-382
Approximately 3·9 kb of DNA, centromere proximal to the previously sequenced Y′ element at the right end of chromosome XV in Saccharomyces cerevisiae strain YP1, has been sequenced. A number of the known sub-telomeric repeat sequences were identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726010dac190e18a7bb45135815faf76
https://doi.org/10.1002/yea.320110410
https://doi.org/10.1002/yea.320110410
Publikováno v:
BMC Molecular Biology
Sealey, D C F, Kostic, A D, LeBel, C, Pryde, F & Harrington, L 2011, ' The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis ', BMC Molecular Biology, vol. 12, 45 . https://doi.org/10.1186/1471-2199-12-45
BMC Molecular Biology, Vol 12, Iss 1, p 45 (2011)
Sealey, D C F, Kostic, A D, LeBel, C, Pryde, F & Harrington, L 2011, ' The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis ', BMC Molecular Biology, vol. 12, 45 . https://doi.org/10.1186/1471-2199-12-45
BMC Molecular Biology, Vol 12, Iss 1, p 45 (2011)
BackgroundThe first telomerase-associated protein (Est1) was isolated in yeast due to its essential role in telomere maintenance. The human counterparts EST1A, EST1B, and EST1C perform diverse functions in nonsense-mediated mRNA decay (NMD), telomere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcc5abe680efe91438a952e06e0f3d2
https://pubmed.ncbi.nlm.nih.gov/22011238
https://pubmed.ncbi.nlm.nih.gov/22011238
Telomere maintenance and survival in saccharomyces cerevisiae in the absence of telomerase and RAD52
Autor:
Catherine LeBel, David C.F. Sealey, David Lydall, Emanuel Rosonina, Fiona E. Pryde, Laura Maringele, Lea Harrington
Publikováno v:
Genetics. 182(3)
Telomeres are essential features of linear genomes that are crucial for chromosome stability. Telomeric DNA is usually replenished by telomerase. Deletion of genes encoding telomerase components leads to telomere attrition with each cycle of DNA repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451a3672d9b805bebd32315e51b3c44b
https://pubmed.ncbi.nlm.nih.gov/19380905
https://pubmed.ncbi.nlm.nih.gov/19380905
Autor:
Edward J. Louis, Ian D. Hickson, Darren Lester, Pei-Hsiu Huang, Rhona H. Borts, Fiona E. Pryde, Rachelle L Maddison
Publikováno v:
Current biology : CB. 11(2)
In S. cerevisiae , mutations in genes that encode telomerase components, such as the genes EST1 , EST2 , EST3, and TLC1, result in the loss of telomerase activity in vivo [1–3]. Two telomerase-independent mechanisms can overcome the resulting senes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72512b8a2e9d4d155a068792c5a4f0d
https://pubmed.ncbi.nlm.nih.gov/11231130
https://pubmed.ncbi.nlm.nih.gov/11231130
Autor:
Meng Fatt Ho, J. Brown, Jean Louis Dufier, Fiona E. Pryde, Lee J. Hardwick, Josseline Kaplan, Alexander J. Edgar, Katherine L. Dry, Shelagh Boyle, Anthony M. Monaco, M A Aldred, Maria A. Musarella, Alan F. Wright, Douglas H. Lester
Publikováno v:
Genomics. 37(2)
The gene responsible for X-linked retinitis pigmentosa (xlRP) in Xp21.1 (RP3) was initially localized by deletion analysis to within a 150- to 170-kb region between the CYBB locus and the proximal deletion junction (BBJ PROX ) from a patient, BB, who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49cdd28a4c7c4923242f83924b853b8
https://pubmed.ncbi.nlm.nih.gov/8921393
https://pubmed.ncbi.nlm.nih.gov/8921393
Autor:
Edward J. Louis, Nicholas A. Kent, Peter W. Inglis, Esther R Loney, Fiona E. Pryde, Jane Mellor, Sarah Sharp
Publikováno v:
Epigenetics & Chromatin
Loney, E R, Inglis, P W, Sharp, S, Pryde, F E, Kent, N A, Mellor, J & Louis, E J 2009, ' Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae ', Epigenetics & chromatin, vol. 2, 18, pp.-. https://doi.org/10.1186/1756-8935-2-18
Oncology Publications
Epigenetics & Chromatin, Vol 2, Iss 1, p 18 (2009)
Loney, E R, Inglis, P W, Sharp, S, Pryde, F E, Kent, N A, Mellor, J & Louis, E J 2009, ' Repressive and non-repressive chromatin at native telomeres in Saccharomyces cerevisiae ', Epigenetics & chromatin, vol. 2, 18, pp.-. https://doi.org/10.1186/1756-8935-2-18
Oncology Publications
Epigenetics & Chromatin, Vol 2, Iss 1, p 18 (2009)
Background In Saccharomyces cerevisiae genes that are located close to a telomere can become transcriptionally repressed by an epigenetic process known as telomere position effect. There is large variation in the level of the telomere position effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bf08c911ac82455ca5d10c0ec7d8ee
http://europepmc.org/articles/PMC3225887
http://europepmc.org/articles/PMC3225887
Autor:
Rebecca Curley, Francesca Romana Mariotti, Alastair R.W. Kerr, Devanshi Jain, Fiona E. Pryde, Maria Vogelauer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 6, p e5882 (2009)
Pryde, F, Jain, D, Kerr, A, Curley, R, Mariotti, F R & Vogelauer, M 2009, ' H3 K36 Methylation Helps Determine the Timing of Cdc45 Association with Replication Origins ', PLoS ONE, vol. 4, no. 6, e5882, pp. 1-13 .
PLoS ONE, Vol 4, Iss 6, p e5882 (2009)
Pryde, F, Jain, D, Kerr, A, Curley, R, Mariotti, F R & Vogelauer, M 2009, ' H3 K36 Methylation Helps Determine the Timing of Cdc45 Association with Replication Origins ', PLoS ONE, vol. 4, no. 6, e5882, pp. 1-13 .
BackgroundReplication origins fire at different times during S-phase. Such timing is determined by the chromosomal context, which includes the activity of nearby genes, telomeric position effects and chromatin structure, such as the acetylation state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf42ac31a3851f5f9584b91186b6b6e2
https://doi.org/10.1371/journal.pone.0005882
https://doi.org/10.1371/journal.pone.0005882