Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Fiona E. Fleming"'
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Detection of viral infection by host cells leads to secretion of type I interferon, which induces antiviral gene expression. The class I major histocompatibility complex (MHCI) is required for viral antigen presentation and subsequent infected cell k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86342063e000e9c864b50755858a1f42
https://doi.org/10.1038/s41598-017-18464-x
https://doi.org/10.1038/s41598-017-18464-x
Autor:
Helen Blanchard, Paul D. Madge, Jaigeeth Deveryshetty, Barbara S. Coulson, Mark von Itzstein, Fiona E. Fleming, Thomas Haselhorst, Gavan Holloway, Xing Yu, Raphael Böhm, Vi T. Dang
Publikováno v:
Journal of Virology. 88:4558-4571
N -acetyl- and N -glycolylneuraminic acids (Sia) and α2β1 integrin are frequently used by rotaviruses as cellular receptors through recognition by virion spike protein VP4. The VP4 subunit VP8*, derived from Wa rotavirus, binds the internal N -acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b523c151cf799f8c683e0249cfef68
https://doi.org/10.1128/jvi.03431-13
https://doi.org/10.1128/jvi.03431-13
Autor:
Vi T. Dang, Xing Yu, Mark von Itzstein, Fiona E. Fleming, Barbara S. Coulson, Helen Blanchard
Publikováno v:
Journal of Virology. 86:13456-13466
The rotavirus spike protein domain VP8* is essential for recognition of cell surface carbohydrate receptors, notably those incorporating N -acylneuraminic acids (members of the sialic acid family). N -Acetylneuraminic acids occur naturally in both an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f20761860d797675900aae605c14cbf
https://doi.org/10.1128/jvi.06975-11
https://doi.org/10.1128/jvi.06975-11
Autor:
Barbara S. Coulson, Kate L. Graham, Helen E. Thomas, Fiona E. Fleming, Jessica A. Pane, Thomas W.H. Kay
Publikováno v:
Scientific Reports
Rotavirus infection is associated with childhood progression to type 1 diabetes. Infection by monkey rotavirus RRV accelerates diabetes onset in non-obese diabetic (NOD) mice, which relates to regional lymph node infection and a T helper 1-specific i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db5677e14f7ca4e7933130e3622dabb
Autor:
Mark von Itzstein, Helen Blanchard, Timm Fiebig, Fiona E. Fleming, Thomas Haselhorst, Barbara S. Coulson, Jeffrey Clifford Dyason
Publikováno v:
Angewandte Chemie. 123:1087-1090
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::044da070429b6fa4b8f0701ce77a528a
https://doi.org/10.1002/ange.201004116
https://doi.org/10.1002/ange.201004116
Autor:
Andrea Bugarcic, Mark J. Kraschnefski, Fiona E. Fleming, Xing Yu, Mark von Itzstein, Helen Blanchard, Barbara S. Coulson
Publikováno v:
Glycobiology. 19:194-200
The rotavirus spike protein VP4 mediates attachment to host cells and subsequent membrane penetration. The VP8(*) domain of VP4 forms the spike tips and is proposed to recognize host-cell surface glycans. For sialidase-sensitive rotaviruses such as r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9c39dac5186bbf1e535ed645c2896f
https://doi.org/10.1093/glycob/cwn119
https://doi.org/10.1093/glycob/cwn119
Publikováno v:
Archives of Virology. 152:1087-1101
Rotavirus outer capsid proteins VP5*, VP8* and VP7 elicit neutralizing, protective antibodies. The α2β1 integrin is a cellular receptor for rotavirus that is bound by VP5*. Some rotaviruses also recognize the α4β1 integrin. In this study, the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::502410a363dda65d0765eb60b002a1ad
https://doi.org/10.1007/s00705-007-0937-x
https://doi.org/10.1007/s00705-007-0937-x
Autor:
Andrea Maggioni, Gavan Holloway, Raphael Böhm, Barbara S. Coulson, Fiona E. Fleming, Thomas Haselhorst, Vi T. Dang, Mark von Itzstein
Publikováno v:
Nature Communications. 6
Histo-blood group antigens (HBGAs) have been proposed as rotavirus receptors. H type-1 and Lewis(b) antigens have been reported to bind VP8* from major human rotavirus genotypes P[4], P[6] and P[8], while VP8* from a rarer P[14] rotavirus recognizes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8361c000bd7d65b4e02f5a163d1dd9
https://doi.org/10.1038/ncomms6907
https://doi.org/10.1038/ncomms6907
Autor:
Mark von Itzstein, Milton J. Kiefel, Fiona E. Fleming, Martin Frank, Jeffrey Clifford Dyason, Alexander Jeffery Szyczew, Mark J. Kraschnefski, Gavan Holloway, Barbara S. Coulson, Helen Blanchard, Thomas Haselhorst
Publikováno v:
Glycobiology. 17:68-81
The VP8* subunit of rotavirus spike protein VP4 contains a sialic acid (Sia)-binding domain important for host cell attachment and infection. In this study, the binding epitope of the N-acetylneuraminic acid (Neu5Ac) derivatives has been characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab706b40e42daf3a1ce4dad92ec7881
https://doi.org/10.1093/glycob/cwl051
https://doi.org/10.1093/glycob/cwl051
Autor:
Kate L. Graham, Yoshikazu Takada, Marilyn J. Hewish, Ian H. Holmes, Fiona E. Fleming, Hadya S. Nagesha, Peter Halasz, Barbara S. Coulson
Publikováno v:
Journal of General Virology. 86:3397-3408
Group A rotaviruses are major intestinal pathogens that express potentialα4β1 andα4β7 integrin ligand sequences Leu–Asp–Val and Leu–Asp–Ile in their outer capsid protein VP7, and Ile–Asp–Ala in their spike protein VP4. Monkey rotaviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe884a7541c181a67d5c8b428e0b0ecb
https://doi.org/10.1099/vir.0.81102-0
https://doi.org/10.1099/vir.0.81102-0