Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Fiona E Freeman"'
Autor:
Jordan C. O’Donoghue, Fiona E. Freeman
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Osteosarcoma is a highly aggressive bone cancer primarily affecting children, adolescents, and young adults. The current gold standard for treatment of osteosarcoma patients consists of two to three rounds of chemotherapy, followed by extensive surgi
Externí odkaz:
https://doaj.org/article/385e3bbc7709433db9283b26492173a9
Autor:
David C. Browe, Ross Burdis, Pedro J. Díaz-Payno, Fiona E. Freeman, Jessica M. Nulty, Conor T. Buckley, Pieter A.J. Brama, Daniel J. Kelly
Publikováno v:
Materials Today Bio, Vol 16, Iss , Pp 100343- (2022)
Articular cartilage defects fail to heal spontaneously, typically progressing to osteoarthritis. Bone marrow stimulation techniques such as microfracture (MFX) are the current surgical standard of care; however MFX typically produces an inferior fibr
Externí odkaz:
https://doaj.org/article/87c2e54468a044dcbcd11fc8165ed03b
Autor:
Fiona E. Freeman, Meadhbh Á. Brennan, David C. Browe, Audrey Renaud, Julien De Lima, Daniel J. Kelly, Laoise M. McNamara, Pierre Layrolle
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
There is a distinct clinical need for new therapies that provide an effective treatment for large bone defect repair. Herein we describe a developmental approach, whereby constructs are primed to mimic certain aspects of bone formation that occur dur
Externí odkaz:
https://doaj.org/article/bf0e78b1e8b84b379f0b53a4593a193d
Autor:
Pedro J. Díaz-Payno, David C. Browe, Fiona E. Freeman, Jessica Nulty, Ross Burdis, Daniel J. Kelly
Publikováno v:
Tissue Engineering Part A. 28:724-736
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dccb51e7cc0265af5ff493245345187e
https://doi.org/10.1089/ten.tea.2021.0176
https://doi.org/10.1089/ten.tea.2021.0176
Autor:
Fiona E. Freeman, Pere Dosta, Lianne C. Shanley, Natalia Ramirez Tamez, Cristobal J. Riojas Javelly, Olwyn R. Mahon, Daniel J. Kelly, Natalie Artzi
Publikováno v:
Advanced Materials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::191b0ba3c0fbf2aa5bc5e1313f6abd5a
https://doi.org/10.1002/adma.202207877
https://doi.org/10.1002/adma.202207877
Autor:
David C. Browe, Pedro J. Díaz-Payno, Fiona E. Freeman, Rossana Schipani, Ross Burdis, Daniel P. Ahern, Jessica M. Nulty, Selcan Guler, Lindsey D. Randall, Conor T. Buckley, Pieter A.J. Brama, Daniel J. Kelly
Publikováno v:
Acta Biomaterialia. 143:266-281
While some clinical advances in cartilage repair have occurred, osteochondral (OC) defect repair remains a significant challenge, with current scaffold-based approaches failing to recapitulate the complex, hierarchical structure of native articular c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3b2dbf8bbb5ffdfd7ce58f6c71be16
https://doi.org/10.1016/j.actbio.2022.03.009
https://doi.org/10.1016/j.actbio.2022.03.009
Autor:
Fiona E. Freeman, Pere Dosta, Cristobal J. Riojas Javelly, Olwyn R. Mahon, Daniel J. Kelly, Natalie Artzi
Patients diagnosed with osteosarcoma undergo extensive surgical intervention and chemotherapy resulting in dismal prognosis and compromised quality of life owing to poor bone regeneration, which is further compromised with chemotherapy delivery. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b24a0f9507c4ec5a1cedc5a003b5dc
https://doi.org/10.1101/2022.09.09.507272
https://doi.org/10.1101/2022.09.09.507272
Autor:
Jessica Nulty, Pedro J. Díaz-Payno, Daniel J. Kelly, Fiona E. Freeman, Bin Wang, David C. Browe, Ross Burdis
Publikováno v:
Acta Biomaterialia. 128:130-142
3D bioprinting has emerged as a promising technology in the field of tissue engineering and regenerative medicine due to its ability to create anatomically complex tissue substitutes. However, it still remains challenging to develop bioactive bioinks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0970de21897b4a373765d4edb70783
https://doi.org/10.1016/j.actbio.2021.04.016
https://doi.org/10.1016/j.actbio.2021.04.016
Autor:
Daniel P. Ahern, Fiona E. Freeman, Pierluca Pitacco, Eben Alsberg, Yu Bin Lee, Ross Burdis, Daniel J. Kelly, Jessica Nulty, David C. Browe
Publikováno v:
Acta Biomaterialia. 126:154-169
For 3D bioprinted tissues to be scaled-up to clinically relevant sizes, effective prevascularisation strategies are required to provide the necessary nutrients for normal metabolism and to remove associated waste by-products. The aim of this study wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb49b55844247af1fbf5af13a4c51fe9
https://doi.org/10.1016/j.actbio.2021.03.003
https://doi.org/10.1016/j.actbio.2021.03.003
Autor:
Ross Burdis, Farhad Chariyev-Prinz, David C. Browe, Fiona E. Freeman, Jessica Nulty, Emily E. McDonnell, Kian F. Eichholz, Bin Wang, Pieter Brama, Daniel J. Kelly
Publikováno v:
Biomaterials. 289:121750
Modular biofabrication strategies using microtissues or organoids as biological building blocks have great potential for engineering replacement tissues and organs at scale. Here we describe the development of a biofabrication strategy to engineer os
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734855ed426d4e8489804ad29696073e
https://doi.org/10.1016/j.biomaterials.2022.121750
https://doi.org/10.1016/j.biomaterials.2022.121750