Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Fiona E, Harrison"'
Autor:
Katrina Volk Robertson, Alec S. Rodriguez, Jean-Philippe Cartailler, Shristi Shrestha, Michael W. Schleh, Kyle R. Schroeder, Arianna M. Valenti, Alec T. Kramer, Fiona E. Harrison, Alyssa H. Hasty
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-24 (2024)
Abstract Background Microglial cell iron load and inflammatory activation are significant hallmarks of late-stage Alzheimer’s disease (AD). In vitro, microglia preferentially upregulate the iron importer, divalent metal transporter 1 (DMT1, gene na
Externí odkaz:
https://doaj.org/article/471d680b763f443b85bdae7d76d2dd8f
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106602- (2024)
Clinical studies have reported that increased epileptiform and subclinical epileptiform activity can be detected in many patients with an Alzheimer's disease (AD) diagnosis using electroencephalogram (EEG) and this may correlate with poorer cognition
Externí odkaz:
https://doaj.org/article/d9daa6365eb34f94b1b87ea48c886a52
Publikováno v:
Optical Materials: X, Vol 24, Iss , Pp 100369- (2024)
We present a new hypothesis and supporting experimental evidence about the essential role played by small impurities of dicarboxystilbene in the process of UV treatment of PET films irradiated with swift heavy ions (SHI). This treatment both forms hi
Externí odkaz:
https://doaj.org/article/3c1e5bd13e914e309ce942853421a4a1
Publikováno v:
Polymers, Vol 15, Iss 20, p 4050 (2023)
We present here a novel experimental study of changes after contact electrification in the optical transmission spectra of samples of both pristine and irradiated PET film treated with Kr+15 ions of energy of 1.75 MeV and a fluence of 3 × 1010 cm2.
Externí odkaz:
https://doaj.org/article/21250171af1147f58350c5ba5f503065
Autor:
William J. Behof, Clayton A. Whitmore, Justin R. Haynes, Adam J. Rosenberg, Mohammed N. Tantawy, Todd E. Peterson, Fiona E. Harrison, Robert B. Beelman, Wellington Pham
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Ergothioneine (ERGO) is a rare amino acid mostly found in fungi, including mushrooms, with recognized antioxidant activity to protect tissues from damage by reactive oxygen species (ROS) components. Prior to this publication, the biodistribu
Externí odkaz:
https://doaj.org/article/9f1da49055e5462fa3b225a7997b562e
Autor:
Heng-Yi Chen, Ana Almonte-Loya, Fang-Yun Lay, Michael Hsu, Eric Johnson, Edahí González-Avalos, Jieyun Yin, Richard S Bruno, Qin Ma, Hazem E Ghoneim, Daniel J Wozniak, Fiona E Harrison, Chan-Wang Jerry Lio
Publikováno v:
eLife, Vol 11 (2022)
Ascorbate (vitamin C) is an essential micronutrient in humans. The severe chronic deficiency of ascorbate, termed scurvy, has long been associated with increased susceptibility to infections. How ascorbate affects the immune system at the cellular an
Externí odkaz:
https://doaj.org/article/c4239ce054af46e581239b891b09faf5
Publikováno v:
Polymers, Vol 15, Iss 4, p 910 (2023)
The novelty of the study is that the ordering that occurs in a PET film under the action of SHI irradiation manifests itself as an increase in the integral intensity of intrinsic luminescence. The Urbach behaviour of the red shift of the absorption e
Externí odkaz:
https://doaj.org/article/d4a73d6b71b5482eb55bf706549e007f
Autor:
Clayton A. Whitmore, Justin R. Haynes, William J. Behof, Adam J. Rosenberg, Mohammed N. Tantawy, Brian C. Hachey, Brian E. Wadzinski, Benjamin W. Spiller, Todd E. Peterson, Krista C. Paffenroth, Fiona E. Harrison, Robert B. Beelman, Printha Wijesinghe, Joanne A. Matsubara, Wellington Pham
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 742 (2022)
Background: Ergothioneine (ERGO) is a unique antioxidant and a rare amino acid available in fungi and various bacteria but not in higher plants or animals. Substantial research data indicate that ERGO is a physiological antioxidant cytoprotectant. Di
Externí odkaz:
https://doaj.org/article/882ef7134def4279bbf43586617325cc
Autor:
Gabriella E. DiCarlo, Samuel J. Mabry, Xixi Cao, Clara McMillan, Tiffany G. Woynaroski, Fiona E. Harrison, India A. Reddy, Heinrich J. G. Matthies, Charles R. Flynn, Mark T. Wallace, Hui Wu, Aurelio Galli
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Background: Altered dopamine (DA) signaling has been associated with autism spectrum disorder (ASD), a neurodevelopmental condition estimated to impact 1 in 54 children in the United States. There is growing evidence for alterations in both gastroint
Externí odkaz:
https://doaj.org/article/badd709b2ac44cdcb483ecb52d827480
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246678 (2021)
Na+,K+-ATPase is a crucial protein responsible for maintaining the electrochemical gradients across the cell membrane. The Na+,K+-ATPase is comprised of catalytic α, β, and γ subunits. In adult brains, the α3 subunit, encoded by ATP1A3, is predom
Externí odkaz:
https://doaj.org/article/f4e2e527b9a44357b7d37719e1ee00b2