Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Fiona C. Mansergh"'
Autor:
Balamurali K. Ambati, David J Keegan, Ruth E Hogg, Fiona C. Mansergh, Malkit K. Singh, Maximilian Padilla, Nathan G. Lambert, Michael A. Wride, Hanan ElShelmani
Publikováno v:
Progress in Retinal and Eye Research. 54:64-102
A biomarker can be a substance or structure measured in body parts, fluids or products that can affect or predict disease incidence. As age-related macular degeneration (AMD) is the leading cause of blindness in the developed world, much research and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b70a628622a37fcdc5a9be0a33699b
https://doi.org/10.1016/j.preteyeres.2016.04.003
https://doi.org/10.1016/j.preteyeres.2016.04.003
Publikováno v:
Visual Neuroscience. 31:289-307
Significant advances have been made over the last decade or two in the elucidation of the molecular pathogenesis of inherited ocular disorders. In particular, remarkable successes have been achieved in exploration of gene-based medicines for these co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaf8b9ec8157040fa5101af66b0e058
https://doi.org/10.1017/s0952523814000133
https://doi.org/10.1017/s0952523814000133
Autor:
Celine Bourdon, Jane Farrar, Roisin Kearney, Fiona C. Mansergh, Despina Bazou, Michael A. Wride
Publikováno v:
Ultrasound in Medicine & Biology
In the present paper, gene expression analysis of mouse embryonic stem (ES) cells levitated in a novel ultrasound standing wave trap (USWT) (Bazou et al. 2005a) at variable acoustic pressures (0.08–0.85 MPa) and times (5–60 min) was performed. Ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670ac153ab40ec4008c28b239e129cf9
Autor:
Peng Mui Iryn Gan, Llinos A Williams, Michael A. Wride, Michael E. Boulton, Lilian Kisiswa, Jenny Geatrell, Martin J. Evans, Miguel Jarrin, Fiona C. Mansergh
Publikováno v:
Experimental Eye Research
Evidence is emerging for apoptosis gene expression in the lens during development. Therefore, here we used a filter array to assess expression of 243 apoptosis-related genes in the developing postnatal mouse lens using 33P labelled cDNA synthesized f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a9c723d2bcb03dc38990e0f39434e60
https://doi.org/10.1016/j.exer.2009.01.020
https://doi.org/10.1016/j.exer.2009.01.020
Publikováno v:
Gut. 56:1410-1414
Background and aims: SPARC (secreted protein acidic, rich in cysteine) is a matricellular protein that has been found to be activated in a number of human cancers. More recently, it has been shown to be upregulated in human gastric and colorectal can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c4842d613977a60fe6ccb3a20c839d0
https://doi.org/10.1136/gut.2006.116921
https://doi.org/10.1136/gut.2006.116921
Autor:
Derrick E. Rancourt, Michael J. Kuiper, Fiona C. Mansergh, Lois M. Mulligan, Michael A. Wride, Scott D. Andrew
Publikováno v:
Gene Function & Disease. 3:1-8
Zinc finger transcription factors play essential roles in neural crest cell development. Even subtle disruptions of the function of these genes could contribute significantly to complex developmental phenotypes such as the multigenic disorder Hirschs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16eed0c7fd011a522d8f032880da7fde
https://doi.org/10.1002/1438-826x(200212)3:3/4<1::aid-gnfd60>3.0.co
https://doi.org/10.1002/1438-826x(200212)3:3/4<1::aid-gnfd60>3.0.co
Autor:
Jamila M. Somani, Michael A. Wride, Fiona C. Mansergh, Derrick E. Rancourt, Robert J. Winkfein
Publikováno v:
Gene. 289:49-59
Transcription factors play important roles in development and homeostasis. We have completed an embryonic stem cell-based neural differentiation screen, which was carried out with a view to isolating early regulators of neurogenesis. Fifty eight of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a8e62945787f57e4d3fca03395cffe
https://doi.org/10.1016/s0378-1119(02)00473-0
https://doi.org/10.1016/s0378-1119(02)00473-0
Publikováno v:
Biochemistry and Cell Biology. 78:613-628
Neurodegenerative diseases cost the economies of the developed world billions of dollars per annum. Given ageing population profiles and the increasing extent of this problem, there has been a surge of interest in neural stem cells and in neural diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::871e72f1a8e2e2d6f863b36e9227ad8c
https://doi.org/10.1139/o00-074
https://doi.org/10.1139/o00-074
Autor:
Derrick E. Rancourt, Gerard Bain, Jackie Hance, S.L. Rancourt, Teruhisa Tsuzuki, William J. Ray, David I. Gottlieb, A. Isogawa, Fiona C. Mansergh, Michael A. Wride, Y. Yoshimura
Publikováno v:
Functional & Integrative Genomics. 1:127-139
We have used a method for synchronously differentiating murine embryonic stem (ES) cells into functional neurons and glia in culture. Using subtractive hybridization we isolated approximately 1200 cDNA clones from ES cell cultures at the neural precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d95e89a5a5f56fb10c486924f6915e4
https://doi.org/10.1007/s101420000014
https://doi.org/10.1007/s101420000014
Autor:
Anna-Sophia Kiang, Peter Humphries, G. Jane Farrar, Avril Kennan, Fiona C. Mansergh, Marian M. Humphries, Paul F. Kenna, Sophia Millington-Ward
Publikováno v:
The American Journal of Human Genetics. 64(4):971-985
SummaryFamily ZMK is a large Irish kindred that segregates progressive sensorineural hearing loss and retinitis pigmentosa. The symptoms in the family are almost identical to those observed in Usher syndrome type III. Unlike that in Usher syndrome ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bf8dd46c2bc0f9ea7159f8b1d27973