Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Fiona Bright"'
Efficient Gene Expression in Human Stem Cell Derived-Cortical Organoids Using Adeno Associated Virus
Publikováno v:
Cells, Vol 11, Iss 20, p 3194 (2022)
Cortical organoids are 3D structures derived either from human embryonic stem cells or human induced pluripotent stem cells with their use exploding in recent years due to their ability to better recapitulate the human brain in vivo in respect to org
Externí odkaz:
https://doaj.org/article/1539950e54e0445ab3eb68881431afc4
Autor:
Fiona Bright, Jared S. Katzeff, John R. Hodges, Olivier Piguet, Jillian J. Kril, Glenda M. Halliday, Woojin Scott Kim
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Behavioral variant frontotemporal dementia (bvFTD) is a younger onset form of neurodegeneration initiated in the frontal and/or temporal lobes with a slow clinical onset but rapid progression. bvFTD is highly complex biologically with different patho
Externí odkaz:
https://doaj.org/article/a7159db1de2a47dc84e8b8c7e5f30555
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7781 (2021)
The abnormal mislocalisation and ubiquitinated protein aggregation of the TAR DNA binding protein 43 (TDP-43) within the cytoplasm of neurons and glia in the central nervous system (CNS) is a pathological hallmark of early-onset neurodegenerative dis
Externí odkaz:
https://doaj.org/article/097a7ebd33c1465ea898fb35eaa4209f
Autor:
Jared S. Katzeff, Fiona Bright, Katherine Phan, Jillian J. Kril, Lars M. Ittner, Michael Kassiou, John R. Hodges, Olivier Piguet, Matthew C. Kiernan, Glenda M. Halliday, Woojin Scott Kim
Publikováno v:
Brain. 145:1598-1609
Frontotemporal dementia refers to a group of neurodegenerative disorders characterized by behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is a rapidly progressing neurodegenerative disease characterized by lo
Autor:
Astrid Feiten, Carol Au, Miheer Sabale, Annika van Hummel, Julia van der Hoven, Yuanyuan Deng, Magdalena Przybyla, Fiona Bright, Troy Butler, Fabien Delerue, Amer Toutonji, Silvia Guglietta, Susanne Wegmann, Bradley T Hyman, Carsten Krieg, Yazi D Ke, Lars Ittner
Background. Amyloid-β (Aβ) and tau form pathogenic lesions in Alzheimer’s disease (AD) brains. As ΑD clinically progresses, tau pathology propagates in a very distinct pattern between connected brain areas. The molecular mechanisms underlying th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f0cfe383990b82595f898855cb4fd2b
https://doi.org/10.21203/rs.3.rs-741896/v2
https://doi.org/10.21203/rs.3.rs-741896/v2
Publikováno v:
Neurodegenerative Diseases Biomarkers ISBN: 9781071617113
Neurodegenerative Diseases Biomarkers
Neurodegenerative Diseases Biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::005d1dd9172052924ce7ae8763df5e77
https://doi.org/10.1007/978-1-0716-1712-0_17
https://doi.org/10.1007/978-1-0716-1712-0_17
Autor:
Lars M. Ittner, Astrid F. Feiten, Bradley T. Hyman, Troy A. Butler, Amer Toutonji, Annika van Hummel, Yuanyuan Deng, Magdalena Przybyla, Julia van der Hoven, Carsten Krieg, Carol G. Au, Silvia Guglietta, Yazi D. Ke, Fabien Delerue, Fiona Bright, Susanne Wegmann
Background. Amyloid-β (Aβ) and tau form pathogenic lesions in Alzheimer’s disease (AD) brains. As ΑD clinically progresses, tau pathology propagates in a very distinct pattern between connected brain areas. The molecular mechanisms underlying th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70168d236b83f670e0034628395173b
https://doi.org/10.21203/rs.3.rs-741896/v1
https://doi.org/10.21203/rs.3.rs-741896/v1
Autor:
Andrew J. Affleck, Claire E. Shepherd, Glenda M. Halliday, Shelley L. Forrest, Milan Kapur, Andrew B. McGeachie, Marloes van Roijen, Yue Huang, Jillian J. Kril, Ciara V. McGinley, Rachel Tan, Heather McCann, Fiona Bright, Anastasia Sizemova
Publikováno v:
Journal of neuropathology and experimental neurology. 79(10)
This study proposes a practical approach, using the minimum number of brain regions and stains, to consolidate previously published neuropathological criteria into one operationalized schema to differentiate subtypes of frontotemporal lobar degenerat
Autor:
Michael Kassiou, Fiona Bright, Glenda M. Halliday, Jillian J. Kril, Matthew C. Kiernan, John R. Hodges, Lars M. Ittner, Ben Crossett, Angela Connolly, Olivier Piguet, Kitty Lo, Clement T. Loy, Woojin S. Kim, Jared S. Katzeff
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases that are considered to be on the same disease spectrum because of overlapping genetic, pathological and clinical traits. Changes in serum proteins in
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7781, p 7781 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The abnormal mislocalisation and ubiquitinated protein aggregation of the TAR DNA binding protein 43 (TDP-43) within the cytoplasm of neurons and glia in the central nervous system (CNS) is a pathological hallmark of early-onset neurodegenerative dis