Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Fiona Brabazon"'
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Insulin is a hormone typically associated with pancreatic release and blood sugar regulation. The brain was long thought to be “insulin-independent,” but research has shown that insulin receptors (IR) are expressed on neurons, microglia and astro
Externí odkaz:
https://doaj.org/article/5a391f060e424f508fed9d79aff87a45
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201878 (2018)
Microglia are the macrophages of the central nervous system (CNS), which function to monitor and maintain homeostasis. Microglial activation occurs after CNS injury, infection or disease. Prolonged microglial activation is detrimental to the CNS as t
Externí odkaz:
https://doaj.org/article/b2b3f7d436c345bba11b407eb124095b
Autor:
Bruce F Bebo, Mark Allegretta, Douglas Landsman, Kathy M Zackowski, Fiona Brabazon, Walter A Kostich, Timothy Coetzee, Alexander Victor Ng, Ruth Ann Marrie, Kelly R Monk, Amit Bar-Or, Caroline C Whitacre
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England). 28(3)
Background: Multiple Sclerosis (MS) is a growing global health challenge affecting nearly 3 million people. Progress has been made in the understanding and treatment of MS over the last several decades, but cures remain elusive. The National MS Socie
Autor:
Shalini Jaiswal, Fiona Brabazon, Ramona von Leden, Deanna Acs, Sean Collier, Nathanael Allison, Bernard Dardzinski, Kimberly R. Byrnes
Publikováno v:
Neuroscience letters. 771
The pathophysiology following spinal cord injury (SCI) progresses from its lesion epicenter resulting in cellular and systemic changes acutely, sub-acutely and chronically. The symptoms of the SCI depend upon the severity of the injury and its locati
Autor:
Kathryn M. DeVeau, Cynthia Gomes, Jeffrey C. Petruska, Eric C. Rouchka, Fiona Brabazon, Scott R. Whittemore, Kathryn A. Harman, Julia H. Chariker, David S.K. Magnuson, Sujata Saraswat Ohri, Michal Hetman
Publikováno v:
Scientific Data, Vol 6, Iss 1, Pp 1-9 (2019)
Scientific Data
Scientific Data
Multi-organ dysfunction is a major complication after spinal cord injury (SCI). In addition to local injury within the spinal cord, SCI causes major disruption to the peripheral organ innervation and regulation. The liver contains sympathetic, parasy
Autor:
Morgan Sharp, Scott R. Whittemore, Cynthia Gomes, Eric C. Rouchka, Kathryn A. Harman, David S.K. Magnuson, Fiona Brabazon, Sujata Saraswat Ohri, Jeffrey C. Petruska, Julia H. Chariker
Publikováno v:
Data in Brief
Reduced muscle mass and increased fatiguability are major complications after spinal cord injury (SCI), and often hinder the rehabilitation efforts of patients. Such detriments to the musculoskeletal system, and the concomitant reduction in level of
Autor:
Reed Selwyn, Fiona Brabazon, Kimberly R. Byrnes, Colin M. Wilson, Sanjeev Mathur, Shalini Jaiswal, Sara Bermudez, Dinesh K Shukla
Publikováno v:
Journal of Neurotrauma. 34:1074-1085
Non-invasive measurements of brain metabolism using 18F-fluorodeoxyglucose (FDG) with positron emission tomography (PET) may provide important information about injury severity following traumatic brain injury (TBI). There is growing interest in the
Autor:
David S.K. Magnuson, Scott R. Whittemore, Eric C. Rouchka, Jeffrey C. Petruska, Julia H. Chariker, Kathryn A. Harman, Fiona Brabazon, Sujata Saraswat Ohri, Cynthia Gomes
Publikováno v:
Scientific Data
Scientific Data, Vol 6, Iss 1, Pp 1-8 (2019)
Scientific Data, Vol 6, Iss 1, Pp 1-8 (2019)
Spinal cord injury (SCI) is a devastating clinical condition resulting in significant disabilities. Apart from local injury within the spinal cord, SCI patients develop a myriad of complications including multi-organ dysfunction. Some of the dysfunct
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201878 (2018)
Microglia are the macrophages of the central nervous system (CNS), which function to monitor and maintain homeostasis. Microglial activation occurs after CNS injury, infection or disease. Prolonged microglial activation is detrimental to the CNS as t
Autor:
Kimberly R. Byrnes, Shalini Jaiswal, Fiona Brabazon, nd William H Frey, John Reed, Colin M. Wilson
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 37(9)
Traumatic brain injury (TBI) results in learning and memory dysfunction. Cognitive deficits result from cellular and metabolic dysfunction after injury, including decreased cerebral glucose uptake and inflammation. This study assessed the ability of