Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma

Autor: Latifa Khalfaoui, Fiona A. Symon, Simon Couillard, Beverley Hargadon, Rekha Chaudhuri, Steve Bicknell, Adel H. Mansur, Rahul Shrimanker, Timothy S. C. Hinks, Ian D. Pavord, Stephen J. Fowler, Vanessa Brown, Lorcan P. McGarvey, Liam G. Heaney, Cary D. Austin, Peter H. Howarth, Joseph R. Arron, David F. Choy, Peter Bradding

Publikováno v: Khalfaoui, L, Symon, F A, Couillard, S, Hargadon, B, Chaudhuri, R, Bicknell, S, Mansur, A H, Shrimanker, R, Hinks, TS C, Pavord, I D, Fowler, S J, Brown, V, McGarvey, L P, Heaney, L G, Austin, C D, Howarth, P H, Arron, J R, Choy, D F & Bradding, P 2022, ' Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma ', Allergy . https://doi.org/10.1111/all.15376
UK Medical Research Council Refractory Asthma Stratification programme (RASP-UK) 2022, ' Airway remodelling rather than cellular infiltration characterises both type2 cytokine biomarker-high and-low severe asthma ', Allergy . https://doi.org/10.1111/all.15376

Background: The most recognizable phenotype of severe asthma comprises people who are blood eosinophil and FeNO-high, driven by type-2 (T2) cytokine biology which responds to targeted biological therapies. However, in many people with severe asthma,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d335eaa0fe9178f81b6b89fe40cd151
https://doi.org/10.1111/all.15376