Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fiona A. Prior"'
Publikováno v:
Vaccine. 28:2687-2692
A binding assay was recently published that differentiates between pertussis toxin (PTx) and the pertussis toxoid (PTd) used in acellular pertussis vaccines based on the selective binding of PTx to fetuin and detection with a polyclonal antibody. We
Publikováno v:
Transgenic Research. 15:261-265
A number of quantitative, real-time PCR methods have been developed for determining transgene copy numbers in plants. Here, we demonstrate that the Roche LightCyclerTM system can be used to determine the zygosity of transgenic lines without the use o
Autor:
Illimar Altosaar, Jelica Mehic, Fiona A. Prior, Suzanne Porter, Margaret Bell, Monika Tocchi, Peter R. Ganz, Ravinder Sardana, Eilleen S. Tackaberry, Anil K. Dudani
Publikováno v:
Genome. 46:521-526
The use of transgenic plants in the production of recombinant proteins for human therapy, including subunit vaccines, is being investigated to evaluate the efficacy and safety of these emerging biopharmaceutical products. We have previously shown tha
Autor:
Fiona A. Prior, Peter R. Ganz, Eilleen S. Tackaberry, K. E. Wright, Ravinder Sardana, Illimar Altosaar, Anil K. Dudani
Publikováno v:
Transgenic Research. 10:177-181
As part of ongoing studies into the use of plant expression systems for making human therapeutic proteins, we have successfully expressed the major glycoprotein, gB, of human cytomegalovirus (HCMV) in transgenic tobacco plants. Viral glycoprotein was
Autor:
Illimar Altosaar, P. R. Ganz, A. K. Dudani, Fiona A. Prior, Ravinder Sardana, Eilleen S. Tackaberry, M Tocchi
Publikováno v:
Vaccine. 17:3020-3029
Plant seeds offer unique opportunities for the production and delivery of oral subunit vaccines. We have used the immunodominant glycoprotein B complex of human cytomegalovirus (HCMV), introduced into tobacco plants, as a model system for studying th
Autor:
Fiona A. Prior, Jelica Mehic, Suzanne Porter, Illimar Altosaar, Karen Rowlandson, Anil K. Dudani, Mark R. Schleiss, P. R. Ganz, Mike Walsh, Monika Tocchi, Ravinder Sardana, Eilleen S. Tackaberry
Publikováno v:
Molecular biotechnology. 40(1)
Production of recombinant subunit vaccines in transgenic plants may be a means of reducing vaccine costs while increasing availability and safety. A plant-derived product found safe and effective for oral administration would provide additional advan