Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Fiona A, Ross"'
Autor:
Fiona A. Ross, James H. Park, David Mansouri, Emilie Combet, Paul G. Horgan, Donald C. McMillan, Campbell S. D. Roxburgh
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Introduction The presence of inflammation is a key hallmark of cancer and, plays an important role in disease progression and survival in colorectal cancer (CRC). Calprotectin detected in the faeces is a sensitive measure of colonic inflamma
Externí odkaz:
https://doaj.org/article/40a7a3489fcb4154a596b27c63d49a59
Autor:
Anees Rahman Cheratta, Faisal Thayyullathil, Simon A. Hawley, Fiona A. Ross, Abdelmajdid Atrih, Douglas J. Lamont, Siraj Pallichankandy, Karthikeyan Subburayan, Ameer Alakkal, Rachid Rezgui, Alex Gray, D. Grahame Hardie, Sehamuddin Galadari
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110761- (2022)
Summary: AMP-activated protein kinase (AMPK) coordinates energy homeostasis during metabolic and energy stress. We report that the catalytic subunit isoform AMPK-α1 (but not α2) is cleaved by caspase-3 at an early stage during induction of apoptosi
Externí odkaz:
https://doaj.org/article/dc89a458593d474787f73e8f3cb61c58
Autor:
Lenore Manderson, Fiona C. Ross
Publikováno v:
Humanities & Social Sciences Communications, Vol 7, Iss 1, Pp 1-9 (2020)
Abstract Despite successful clinical interventions and maternal and child health monitoring for over a century, low and middle-income countries, including South Africa, continue to experience the quadruple burden of disease of high maternal mortality
Externí odkaz:
https://doaj.org/article/537e5180fa974ee7bce53a8d3842eaff
Autor:
Fiona C. Ross
Publikováno v:
South African Journal of Science (2020)
This Commentary is a response to a Commentary published in the May/June 2020 issue: Nattrass N. Why are black South African students less likely to consider studying biological sciences? S Afr J Sci. 2020;116(5/6), Art. #7864, 2 pages. https://doi
Externí odkaz:
https://doaj.org/article/47cc9e89c34e4f7c8c2abc6f0da781ca
Autor:
Molly Went, Amit Sud, Asta Försti, Britt-Marie Halvarsson, Niels Weinhold, Scott Kimber, Mark van Duin, Gudmar Thorleifsson, Amy Holroyd, David C. Johnson, Ni Li, Giulia Orlando, Philip J. Law, Mina Ali, Bowang Chen, Jonathan S. Mitchell, Daniel F. Gudbjartsson, Rowan Kuiper, Owen W. Stephens, Uta Bertsch, Peter Broderick, Chiara Campo, Obul R Bandapalli, Hermann Einsele, Walter A. Gregory, Urban Gullberg, Jens Hillengass, Per Hoffmann, Graham H. Jackson, Karl-Heinz Jöckel, Ellinor Johnsson, Sigurður Y. Kristinsson, Ulf-Henrik Mellqvist, Hareth Nahi, Douglas Easton, Paul Pharoah, Alison Dunning, Julian Peto, Federico Canzian, Anthony Swerdlow, Rosalind A. Eeles, ZSofia Kote-Jarai, Kenneth Muir, Nora Pashayan, Jolanta Nickel, Markus M. Nöthen, Thorunn Rafnar, Fiona M. Ross, Miguel Inacio da Silva Filho, Hauke Thomsen, Ingemar Turesson, Annette Vangsted, Niels Frost Andersen, Anders Waage, Brian A. Walker, Anna-Karin Wihlborg, Annemiek Broyl, Faith E. Davies, Unnur Thorsteinsdottir, Christian Langer, Markus Hansson, Hartmut Goldschmidt, Martin Kaiser, Pieter Sonneveld, Kari Stefansson, Gareth J. Morgan, Kari Hemminki, Björn Nilsson, Richard S. Houlston, The PRACTICAL consortium
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Multiple myeloma is a cancer of the plasma cells, and the complete aetiology of the disease is still unclear. Here the authors perform an additional GWAS analysis followed by a meta-analysis with existing GWAS and replication genotyping and identify
Externí odkaz:
https://doaj.org/article/af73d8d01835421aac1fd29b48af6093
Autor:
Molly Went, Amit Sud, Asta Försti, Britt-Marie Halvarsson, Niels Weinhold, Scott Kimber, Mark van Duin, Gudmar Thorleifsson, Amy Holroyd, David C. Johnson, Ni Li, Giulia Orlando, Philip J. Law, Mina Ali, Bowang Chen, Jonathan S. Mitchell, Daniel F. Gudbjartsson, Rowan Kuiper, Owen W. Stephens, Uta Bertsch, Peter Broderick, Chiara Campo, Obul R Bandapalli, Hermann Einsele, Walter A. Gregory, Urban Gullberg, Jens Hillengass, Per Hoffmann, Graham H. Jackson, Karl-Heinz Jöckel, Ellinor Johnsson, Sigurður Y. Kristinsson, Ulf-Henrik Mellqvist, Hareth Nahi, Douglas Easton, Paul Pharoah, Alison Dunning, Julian Peto, Federico Canzian, Anthony Swerdlow, Rosalind A. Eeles, Zsofia Kote-Jarai, Kenneth Muir, Nora Pashayan, The PRACTICAL consortium, Jolanta Nickel, Markus M. Nöthen, Thorunn Rafnar, Fiona M. Ross, Miguel Inacio da Silva Filho, Hauke Thomsen, Ingemar Turesson, Annette Vangsted, Niels Frost Andersen, Anders Waage, Brian A. Walker, Anna-Karin Wihlborg, Annemiek Broyl, Faith E. Davies, Unnur Thorsteinsdottir, Christian Langer, Markus Hansson, Hartmut Goldschmidt, Martin Kaiser, Pieter Sonneveld, Kari Stefansson, Gareth J. Morgan, Kari Hemminki, Björn Nilsson, Richard S. Houlston
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-3 (2019)
The original version of this Article contained an error in the spelling of a member of the PRACTICAL Consortium, Manuela Gago-Dominguez, which was incorrectly given as Manuela Gago Dominguez. This has now been corrected in both the PDF and HTML versi
Externí odkaz:
https://doaj.org/article/c1d3a611c8a4407e930cd1dd4d9814f3
Autor:
D. Grahame Hardie, Graeme J. Gowans, Alexander Gray, Diana Vara Ciruelos, Fiona A. Ross, Sarah Fogarty
The AMP-activated protein kinase (AMPK) is activated by phosphorylation at Thr172, either by the tumor suppressor kinase LKB1 or by an alternate pathway involving the Ca2+/calmodulin-dependent kinase, CAMKK2. Increases in AMP:ATP and ADP:ATP ratios,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b57d6fa029e3ecaeee2012b9207f6e5
https://doi.org/10.1158/1541-7786.c.6539973.v1
https://doi.org/10.1158/1541-7786.c.6539973.v1
Autor:
D. Grahame Hardie, Graeme J. Gowans, Alexander Gray, Diana Vara Ciruelos, Fiona A. Ross, Sarah Fogarty
Cellular stresses that increase AMP:ATP and AMP:ATP ratios activate AMPK in normal cells by promoting its phosphorylation by LKB1. This triggers inhibition of cell growth by phosphorylation of acetyl-CoA carboxylase (ACC), Raptor and other targets, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7f096a646d6fa9fa5b00f7f6db98c1
https://doi.org/10.1158/1541-7786.22511550
https://doi.org/10.1158/1541-7786.22511550
Autor:
Gareth J. Morgan, Faith E. Davies, Fiona M. Ross, Walter M. Gregory, David Gonzalez, Kevin D. Boyd, Matthew W. Jenner, Athanasia Zeisig, José L. Brito, David C. Johnson, Paola E. Leone, Brian A. Walker, Nicholas J. Dickens
Adobe PDF - Supplementary_Data.pdf from Homozygous Deletion Mapping in Myeloma Samples Identifies Genes and an Expression Signature Relevant to Pathogenesis and Outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b57e03859afabee5ae80e3524e91f3b
https://doi.org/10.1158/1078-0432.22442685.v1
https://doi.org/10.1158/1078-0432.22442685.v1
Autor:
Gareth J. Morgan, Faith E. Davies, Alex J. Szubert, Walter M. Gregory, Christopher P. Wardell, Brian A. Walker, William J. Tapper, Zoe J. Konn, GianPaolo Dagrada, Laura Chiecchio, Fiona M. Ross, Kevin D. Boyd
Supplementary Table 2 from Gender Disparities in the Tumor Genetics and Clinical Outcome of Multiple Myeloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffb3d5c8d7fafa3f4dfdb9af1b351fb
https://doi.org/10.1158/1055-9965.22435494
https://doi.org/10.1158/1055-9965.22435494