Výsledky vyhledávání - "Fiona, Cuskin"

Analysis of glycans in a Burnt-on/Baked-on (BoBo) model food soil using Microarray Polymer Profiling (MAPP) and immunofluorescence microscopy

Autor: Cassie R, Bakshani, Fiona, Cuskin, Neil J, Lant, Hamish C L, Yau, William G T, Willats, J, Grant Burgess

Publikováno v: Food Chemistry. 410:135379

Burning of food materials during cooking can increase the difficulty in removal from solid surfaces, forming residual food soils. Using molecular probe-based technologies, the aim of this work was to elucidate the composition and relative abundance o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0868a5151d4a81ecf317d31118bc59d
https://doi.org/10.1016/j.foodchem.2022.135379

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A Bacteroidetes locus dedicated to fungal 1,6-β-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-β-glucanase

Autor: Fiona Cuskin, Max J. Temple, Elisabeth C. Lowe, Niall A. Hickey, Spencer J. Williams, Arnaud Baslé, Harry J. Gilbert, Gaetano Speciale

Publikováno v: The Journal of Biological Chemistry

Glycans are major nutrients available to the human gut microbiota. The Bacteroides are generalist glycan degraders, and this function is mediated largely by polysaccharide utilization loci (PULs). The genomes of several Bacteroides species contain a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f9b5d7a3b3b658009b6bc4fa85e206
http://europepmc.org/articles/PMC5481569

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Structure of the GH76 α-mannanase homolog, BT2949, from the gut symbiont Bacteroides thetaiotaomicron

Autor: R.J. Spears, Gideon J. Davies, Jerome Dabin, Harry J. Gilbert, Fiona Cuskin, Andrew J. Thompson, Johan P. Turkenburg

Publikováno v: Acta Crystallographica Section D: Biological Crystallography

A high-resolution structure of a noncanonical α-mannanase relevant to human health and nutrition has been solved via heavy-atom phasing of a selenomethionine derivative.
The large bowel microbiota, a complex ecosystem resident within the gastro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7bbdc781b386982e3ebeb4a37bec8a2
http://europepmc.org/articles/PMC4321491

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A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-inflammatory Gene Signature in Macrophages

Autor: Camille, Danne, Grigory, Ryzhakov, Maria, Martínez-López, Nicholas Edward, Ilott, Fanny, Franchini, Fiona, Cuskin, Elisabeth C, Lowe, Samuel J, Bullers, J Simon C, Arthur, Fiona, Powrie

Publikováno v: Microbial Cell

A high density of microbes inhabits the intestine, helping with food digestion, vitamin synthesis, xenobiotic detoxification, pathogen resistance and immune system maturation. Crucial for human health, communities of commensal bacteria (collectively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d050e9e11784829cb101d8a04959fba7
https://pubmed.ncbi.nlm.nih.gov/29611556

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Diverse specificity of cellulosome attachment to the bacterial cell surface

Autor: Holly L. Spencer, Shabir Najmudin, Kate Cameron, Joana L. A. Brás, Carlos M. G. A. Fontes, Virgínia M. R. Pires, Aldino Viegas, Pedro Bule, Benedita A. Pinheiro, Victor D. Alves, Steven P. Smith, Edward A. Bayer, Harry J. Gilbert, Fiona Cuskin, Maria João Romão, Ana Luísa Carvalho

Publikováno v: Scientific Reports
'Scientific Reports ', vol: 6, pages: 38292-1-38292-12 (2016)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

This work was supported by the EU FP7 programme under the WallTraC project (grant No. 263916) and by projects PTDC/BIA-MIC/5947/2014, RECI/BBB-BEP/0124/2012 and EXPL/BIA-MIC/1176/2012 supported by Fundacao para a Ciencia e Tecnologia (FCT-MCTES). The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de95a2bf04bd19655bb57581a141846
https://pubmed.ncbi.nlm.nih.gov/27924829

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Coevolution of yeast mannan digestion: Convergence of the civilized human diet, distal gut microbiome, and host immunity

Autor: D. Wade Abbott, Harry J. Gilbert, Elisabeth C. Lowe, Fiona Cuskin, Eric C. Martens

Publikováno v: Gut microbes. 6(5)

The complex carbohydrates accessible to the distal gut microbiota (DGM) are key drivers in determining the structure of this ecosystem. Typically, plant cell wall polysaccharides and recalcitrant starch (i.e. dietary fiber), in addition to host glyca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a577c954e4766b4ed93a932eb707ac
https://pubmed.ncbi.nlm.nih.gov/26440374

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The GH130 family of mannoside phosphorylases contains glycoside hydrolases that target beta-1,2 mannosidic linkages in Candida mannan

Autor: Simon Ladevèze, Gideon J. Davies, Elisabeth C. Lowe, Harry J. Gilbert, Alison M. Day, Gabrielle Potocki-Véronèse, Fiona Cuskin, Arnaud Baslé

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2015
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2015, 290 (41), ⟨10.1074/jbc.M115.681460⟩
Journal of Biological Chemistry 41 (290), 25023-25033. (2015)
The Journal of Biological Chemistry
Journal of Biological Chemistry, 2015, 290 (41), ⟨10.1074/jbc.M115.681460⟩

Background: A cohort of a family of mannose phosphorylases lack phosphate binding residues, suggesting that they display non-phosphorylase activities. Results: The non-phosphorylase enzymes were shown to be β-mannosidases. Conclusion: Replacing basi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6788326665642b1be5108a9bbbc6b65c
https://hal.archives-ouvertes.fr/hal-01184120

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