Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Fion Wan-Yee Sin"'
Autor:
Paul Ha-Sang Pang, Ray Chun-Fai Chan, Yong Xie, Fion Wan-Yee Sin, Kin-Tak Chan, Zhihong Guo, Luigi Ying-Wai Tse, Ying-Kit Cheung
Publikováno v:
Cancer Letters. 256:178-185
HCA661 is a cancer-testis (CT) antigen frequently expressed in human hepatocellular carcinoma (HCC). To search for immunogenic peptides of HCA661, bioinformatics analysis and CD8(+) T cell IFN-gamma ELISPOT assay were employed, and two HLA-A *0201 re
Publikováno v:
Vaccine
The severe acute respiratory syndrome coronavirus nucleocapsid protein (SARS-CoV N) is one of the major targets for SARS vaccine due to its high potency in triggering immune responses. In this study, we have identified a novel HLA-A*0201 restricted e
Publikováno v:
Vaccine. 23:629-638
Human papillomavirus Type 16 (HPV16) infections can cause neoplasia, which is thought to be closely associated with the development of cervical cancers. In the study, we attempted to construct a DNA plasmid encoding a HPV16 capsid protein (L1) and a
Autor:
Ho Tsun Wong, Fion Wan-Yee Sin, Samuel Chak-Sum Cheng, Yong Xie, E. W. C. Chan, Zu Tian Sheng
Publikováno v:
Vaccine. 20:2641-2647
A plasmid DNA vaccine candidate (pCEIS) encoding two foot-and-mouth disease virus (FMDV) VP1 epitopes (amino acid residues 141-160 and 200-213) has been demonstrated to have the ability to elicit both FMDV-specific T cell proliferation and neutralizi
Publikováno v:
Toxicology Letters. 122:81-87
Triptolide, a traditional Chinese medicine, has been reported to be effective in the treatment of auto-immune diseases, and it can also induce anti-neoplastic activity on several human tumor cell lines. This study investigates the cytotoxic function
Autor:
Samuel Chak-Sum Cheng, Chenjie Zeng, Kin-Tak Chan, Fion Wan-Yee Sin, Yaling Hu, Yan Ke, Yong Xie, Bofu Xue
Publikováno v:
Biochemical and biophysical research communications. 392(3)
Scavenger receptor A (SR-A) plays a crucial role in affecting the dendritic cell-mediated presentation of cancer testis antigens to T cells against human cancer cells. Here we use a dendritic cell-mediated model to verify that a sulphated polysacchar
Autor:
Yi Xie, Yong Xie, Ying-Kit Cheung, Fion Wan-Yee Sin, Kin-Tak Chan, Li-Hua Xie, Samuel Chak-Sum Cheng
Publikováno v:
Cancer immunology, immunotherapy : CII. 57(7)
Induction of anti-tumor immune responses by dendritic cells (DCs) transduced with a recombinant adeno-associated virus type 2 (rAAV2) encoding tumor antigens is considered a promising approach for cancer vaccine development. CML28, a novel antigen wi
Publikováno v:
Cancer Immunology, Immunotherapy; Jul2008, Vol. 57 Issue 7, p1029-1038, 10p, 1 Black and White Photograph, 1 Chart, 4 Graphs