Empagliflozin decreases myocardial cytoplasmic Na ⁺ through inhibition of the cardiac Na ⁺ /H ⁺ exchanger in rats and rabbits.

Autor: Baartscheer A; Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Schumacher CA; Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Wüst RC; Department of Physiology, Institute for Cardiovascular Research, VU University Medical Centre, Amsterdam, the Netherlands.; Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Fiolet JW; Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Stienen GJ; Department of Physiology, Institute for Cardiovascular Research, VU University Medical Centre, Amsterdam, the Netherlands.; Department of Physics and Astronomy, Faculty of Science, VU University, Amsterdam, the Netherlands., Coronel R; Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.; University of Bordeaux, L'Institut du Rythmologie et Modélisation Cardiaque (LIRYC), Bordeaux, France., Zuurbier CJ; Department of Anesthesiology, Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands. c.j.zuurbier@amc.uva.nl.

Publikováno v: Diabetologia [Diabetologia] 2017 Mar; Vol. 60 (3), pp. 568-573. Date of Electronic Publication: 2016 Oct 17.

Atrial fibrosis and conduction slowing in the left atrial appendage of patients undergoing thoracoscopic surgical pulmonary vein isolation for atrial fibrillation.

Autor: Krul SP; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., Berger WR; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., Smit NW; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., van Amersfoorth SC; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., Driessen AH; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., van Boven WJ; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., Fiolet JW; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., van Ginneken AC; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., van der Wal AC; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., de Bakker JM; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., Coronel R; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.)., de Groot JR; From the Heart Center, Departments of Clinical and Experimental Cardiology (S.P.J.K., W.R.B., N.W.S., S.C.M.v.A., J.W.T.F., J.M.T.d.B., R.C., J.R.d.G.) and Cardiothoracic Surgery (A.H.G.D., W.J.v.B.), Departments of Anatomy, Embryology, and Physiology (A.C.G.v.G.) and Pathology (A.C.v.d.W.), Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands (J.M.T.d.B.); and L'Institut de RYthmologie et Modélisation Cardiaque (LIRYC), Université de Bordeaux, Bordeaux, France (R.C.). j.r.degroot@amc.uva.nl.

Publikováno v: Circulation. Arrhythmia and electrophysiology [Circ Arrhythm Electrophysiol] 2015 Apr; Vol. 8 (2), pp. 288-95. Date of Electronic Publication: 2015 Feb 11.

The Driving Force of the Na/Ca-Exchanger during Metabolic Inhibition.

Autor: Baartscheer A; Experimental Cardiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam Amsterdam, Netherlands., Schumacher CA, Coronel R, Fiolet JW

Publikováno v: Frontiers in physiology [Front Physiol] 2011 Mar 11; Vol. 2, pp. 10. Date of Electronic Publication: 2011 Mar 11 (Print Publication: 2011).

Acute administration of fish oil inhibits triggered activity in isolated myocytes from rabbits and patients with heart failure.

Autor: Den Ruijter HM; Department of Experimental Cardiology, Center for Heart Failure Research, Academic Medical Center, Room K2-113, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. h.m.denruijter@amc.uva.nl, Berecki G, Verkerk AO, Bakker D, Baartscheer A, Schumacher CA, Belterman CN, de Jonge N, Fiolet JW, Brouwer IA, Coronel R

Publikováno v: Circulation [Circulation] 2008 Jan 29; Vol. 117 (4), pp. 536-44. Date of Electronic Publication: 2008 Jan 14.

Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials.

Autor: Verkerk AO; Experimental and Molecular Cardiology Group, Academic Medical Center, University of Amsterdam, The Netherlands., van Ginneken AC, Berecki G, den Ruijter HM, Schumacher CA, Veldkamp MW, Baartscheer A, Casini S, Opthof T, Hovenier R, Fiolet JW, Zock PL, Coronel R

Publikováno v: Cardiovascular research [Cardiovasc Res] 2006 Jun 01; Vol. 70 (3), pp. 509-20. Date of Electronic Publication: 2006 Feb 28.