Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Finn, Kirpekar"'
Autor:
Marina Alexeeva, Marivi Nabong Moen, Xiang Ming Xu, Anette Rasmussen, Ingar Leiros, Finn Kirpekar, Arne Klungland, Lene Alsøe, Hilde Nilsen, Svein Bjelland
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Uracil arises in cellular DNA by cytosine (C) deamination and erroneous replicative incorporation of deoxyuridine monophosphate opposite adenine. The former generates C → thymine transition mutations if uracil is not removed by uracil-DNA glycosyla
Externí odkaz:
https://doaj.org/article/d7f045b476d94cb59da2ab03aa3d7809
Autor:
Ashley A. Rowden, Logan M. Peoples, Clemens Schauberger, Bo Thamdrup, Frank Wenzhöfer, Morten Larsen, Mathias Middelboe, Ronnie N. Glud, Finn Kirpekar, Douglas H. Bartlett
Publikováno v:
Limnology and Oceanography
LIMNOLOGY AND OCEANOGRAPHY
EPIC3Limnology and Oceanography, AMER SOC LIMNOLOGY OCEANOGRAPHY, 66, pp. 2095-2109, ISSN: 0024-3590
Schauberger, C, Middelboe, M, Larsen, M, Peoples, L M, Bartlett, D H, Kirpekar, F, Rowden, A A, Wenzhöfer, F, Thamdrup, B & Glud, R N 2021, ' Spatial variability of prokaryotic and viral abundances in the Kermadec and Atacama Trench regions ', Limnology and Oceanography, vol. 66, no. 6, pp. 2095-2109 . https://doi.org/10.1002/lno.11711
LIMNOLOGY AND OCEANOGRAPHY
EPIC3Limnology and Oceanography, AMER SOC LIMNOLOGY OCEANOGRAPHY, 66, pp. 2095-2109, ISSN: 0024-3590
Schauberger, C, Middelboe, M, Larsen, M, Peoples, L M, Bartlett, D H, Kirpekar, F, Rowden, A A, Wenzhöfer, F, Thamdrup, B & Glud, R N 2021, ' Spatial variability of prokaryotic and viral abundances in the Kermadec and Atacama Trench regions ', Limnology and Oceanography, vol. 66, no. 6, pp. 2095-2109 . https://doi.org/10.1002/lno.11711
Hadal trenches represent the deepest part of the ocean and are dynamic depocenters with intensified prokaryotic activity. Here, we explored the distribution and drivers of prokaryotic and viral abundance from the ocean surface and 40 cm into sediment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e30dc09a47d6c2db63e180f998bac1e
https://doi.org/10.1002/lno.11711
https://doi.org/10.1002/lno.11711
Autor:
Carsten Jers, Malwina Michalak, Dorte M Larsen, Kasper P Kepp, Haiying Li, Yao Guo, Finn Kirpekar, Anne S Meyer, Jørn D Mikkelsen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83902 (2014)
This paper reports rational engineering of Trypanosoma rangeli sialidase to develop an effective enzyme for a potentially important type of reactivity: production of sialylated prebiotic glycans. The Trypanosoma cruzi trans-sialidase and the homologo
Externí odkaz:
https://doaj.org/article/7ce5c01b05ce4c2b82b60c94e2281430
Autor:
Daria Zdżalik, Cathrine B Vågbø, Finn Kirpekar, Erna Davydova, Alicja Puścian, Agnieszka M Maciejewska, Hans E Krokan, Arne Klungland, Barbara Tudek, Erwin van den Born, Pål Ø Falnes
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98729 (2014)
The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno adducts on the nucleobases.
Externí odkaz:
https://doaj.org/article/b2fee403fcd749dabb5b49aae995b66c
Autor:
Lang Sun, Xiaojing Guo, Tanxi Cai, Yinlei Bai, Zhensheng Xie, Pernille Kronholm Rasmussen, Xuefu You, Jifeng Wang, Nali Zhu, Xiang Ding, Finn Kirpekar, Xiulan Chen, Lili Niu, Fuquan Yang
Publikováno v:
Antimicrob Agents Chemother
Sun, L, Rasmussen, P K, Bai, Y, Chen, X, Cai, T, Wang, J, Guo, X, Xie, Z, Ding, X, Niu, L, Zhu, N, You, X, Kirpekar, F & Yang, F 2020, ' Proteomic Changes of Klebsiella pneumoniae in Response to Colistin Treatment and crrB Mutation-Mediated Colistin Resistance ', Antimicrobial Agents and Chemotherapy, vol. 64, no. 6, e02200-19 . https://doi.org/10.1128/AAC.02200-19
Sun, L, Rasmussen, P K, Bai, Y, Chen, X, Cai, T, Wang, J, Guo, X, Xie, Z, Ding, X, Niu, L, Zhu, N, You, X, Kirpekar, F & Yang, F 2020, ' Proteomic Changes of Klebsiella pneumoniae in Response to Colistin Treatment and crrB Mutation-Mediated Colistin Resistance ', Antimicrobial Agents and Chemotherapy, vol. 64, no. 6, e02200-19 . https://doi.org/10.1128/AAC.02200-19
Polymyxins are increasingly used as the critical last-resort therapeutic options for multidrug-resistant Gram-negative bacteria. Unfortunately, polymyxin resistance has increased gradually over the past few years. Although studies on polymyxin mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741b9ba3b059fd5355008cd5bc04b3a0
https://europepmc.org/articles/PMC7269499/
https://europepmc.org/articles/PMC7269499/
Autor:
Birte Vester, Finn Kirpekar, Julie Mundus, Stine Tryggedsson, Eleni Ntokou, Patricia Teixeira Dos Santos, Lykke Haastrup Hansen
Publikováno v:
Kirpekar, F, Hansen, L H, Mundus, J, Tryggedsson, S, Teixeira Dos Santos, P, Ntokou, E & Vester, B 2018, ' Mapping of ribosomal 23S ribosomal RNA modifications in Clostridium sporogenes ', RNA Biology, vol. 15, no. 8, pp. 1060–1070 . https://doi.org/10.1080/15476286.2018.1486662
All organisms contain RNA modifications in their ribosomal RNA (rRNA), but the importance, positions and exact function of these are still not fully elucidated. Various functions such as stabilizing structures, controlling ribosome assembly and facil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0a0892f344215a8bdab0fa6d961717
https://doi.org/10.1080/15476286.2018.1486662
https://doi.org/10.1080/15476286.2018.1486662
Autor:
Stephen Douthwaite, Finn Kirpekar, Jesper F. Havelund, Simon Rose, Harald Huber, Sylvie Auxilien, Henri Grosjean
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (12), pp.6906--6918. ⟨10.1093/nar/gkaa411⟩
Rose, S, Auxilien, S, Havelund, J F, Kirpekar, F, Huber, H, Grosjean, H & Douthwaite, S 2020, ' The hyperthermophilic partners Nanoarchaeum and Ignicoccus stabilize their tRNA T-loops via different but structurally equivalent modifications ', Nucleic acids research, vol. 48, no. 12, pp. 6906-6918 . https://doi.org/10.1093/nar/gkaa411
Nucleic Acids Research, 2020, 48 (12), pp.6906--6918. ⟨10.1093/nar/gkaa411⟩
Rose, S, Auxilien, S, Havelund, J F, Kirpekar, F, Huber, H, Grosjean, H & Douthwaite, S 2020, ' The hyperthermophilic partners Nanoarchaeum and Ignicoccus stabilize their tRNA T-loops via different but structurally equivalent modifications ', Nucleic acids research, vol. 48, no. 12, pp. 6906-6918 . https://doi.org/10.1093/nar/gkaa411
Place: Oxford Publisher: Oxford Univ Press WOS:000574288800042; The universal L-shaped tertiary structure of tRNAs is maintained with the help of nucleotide modifications within the D- and T-loops, and these modifications are most extensive within hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b76e995c76b279dd947f01251ee9ff
https://hal.archives-ouvertes.fr/hal-02968376
https://hal.archives-ouvertes.fr/hal-02968376
Autor:
Finn Kirpekar, Anders Albrechtsen, Line Dahl Poulsen, Christel Enroth, Jeppe Vinther, Søren Iversen
Publikováno v:
Enroth, C, Poulsen, L D, Iversen, S, Kirpekar, F, Albrechtsen, A & Vinther, J 2019, ' Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing ', Nucleic acids research, vol. 47, no. 20, e126 . https://doi.org/10.1093/nar/gkz736
Nucleic Acids Research
Enroth, C, Poulsen, L D, Iversen, S, Kirpekar, F, Albrechtsen, A & Vinther, J 2019, ' Detection of internal N7-methylguanosine (m 7 G) RNA modifications by mutational profiling sequencing ', Nucleic Acids Research, vol. 47, no. 20, e126 . https://doi.org/10.1093/nar/gkz736
Nucleic Acids Research
Enroth, C, Poulsen, L D, Iversen, S, Kirpekar, F, Albrechtsen, A & Vinther, J 2019, ' Detection of internal N7-methylguanosine (m 7 G) RNA modifications by mutational profiling sequencing ', Nucleic Acids Research, vol. 47, no. 20, e126 . https://doi.org/10.1093/nar/gkz736
Methylation of guanosine on position N7 (m7G) on internal RNA positions has been found in all domains of life and have been implicated in human disease. Here, we present m7G Mutational Profiling sequencing (m7G-MaP-seq), which allows high throughput
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad865d1de5bdcf043ec06b49d74dc68c
https://findresearcher.sdu.dk:8443/ws/files/157065331/gkz736.pdf
https://findresearcher.sdu.dk:8443/ws/files/157065331/gkz736.pdf
Autor:
Marina Alexeeva, Peter Ruoff, Izaskun Muruzábal-Lecumberri, Kristin Grøsvik, Xiang Ming Xu, Almaz Nigatu Tesfahun, Arne Klungland, Anette Rasmussen, Marivi N. Moen, Finn Kirpekar, Kristine M. Olsen, Svein Bjelland
Publikováno v:
Alexeeva, M, Moen, M N, Grøsvik, K, Tesfahun, A N, Xu, X M, Muruzábal-Lecumberri, I, Olsen, K M, Rasmussen, A, Ruoff, P, Kirpekar, F, Klungland, A & Bjelland, S 2019, ' Excision of uracil from DNA by hSMUG1 includes strand incision and processing ', Nucleic Acids Research, vol. 47, no. 2, pp. 779-793 . https://doi.org/10.1093/nar/gky1184
Nucleic Acids Research
Nucleic Acids Research
Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. The base excision repair (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75365a8bc8f013d98f4a9e88573fb64b
http://hdl.handle.net/10852/71387
http://hdl.handle.net/10852/71387
Autor:
Anis Arnous, Anne S. Meyer, Jørn Dalgaard Mikkelsen, Yao Guo, Haiying Li, Finn Kirpekar, Carsten Jers
Publikováno v:
Guo, Y, Jers, C, Meyer, A S, Arnous, A, Li, H, Kirpekar, F & Mikkelsen, J D 2014, ' A Pasteurella multocida sialyltransferase displaying dual trans-sialidase activities for production of 3'-sialyl and 6'-sialyl glycans ', Journal of Biotechnology, vol. 170, pp. 60-67 . https://doi.org/10.1016/j.jbiotec.2013.11.013
This study examined a recombinant Pasteurella multocida sialyltransferase exhibiting dual trans-sialidase activities. The enzyme catalyzed trans-sialylation using either 2-O-(p-nitrophenyl)-α-d-N-acetylneuraminic acid or casein glycomacropeptide (wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a119d78f5e9d328f93081308e58edb5b
https://doi.org/10.1016/j.jbiotec.2013.11.013
https://doi.org/10.1016/j.jbiotec.2013.11.013