Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Finkelstein DI"'
Autor:
Billings, JL, Gordon, SL, Rawling, T, Doble, PA, Bush, AI, Adlard, PA, Finkelstein, DI, Hare, DJ
© 2019 International Society for Neurochemistry Treatment with the dopamine (DA) precursor l-3,4-dihydroxyphenylalanine (l-DOPA) provides symptomatic relief arising from DA denervation in Parkinson's disease. Mounting evidence that DA autooxidation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e4751d9bdad1eb5a197b1f582fd69112
https://hdl.handle.net/10453/135825
https://hdl.handle.net/10453/135825
© 2017 The Royal Society of Chemistry. The biological transition metals iron (Fe), copper (Cu) and zinc (Zn) are thought to contribute to the neuronal pathologies that occur following traumatic brain injury (TBI), and indeed our previously published
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::80a7d7a97e0f9d6d67e2abf0549d65d1
https://hdl.handle.net/10453/111982
https://hdl.handle.net/10453/111982
Autor:
Portbury, SD, Hare, DJ, Sgambelloni, C, Perronnes, K, Portbury, AJ, Finkelstein, DI, Adlard, PA
This study assessed the therapeutic utility of the autophagy enhancing stable disaccharide trehalose in the Tg2576 transgenic mouse model of Alzheimer's disease (AD) via an oral gavage of a 2% trehalose solution for 31 days. Furthermore, as AD is a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::4c5c6277330eff444ba7ba7ee4a393a5
https://hdl.handle.net/10453/159718
https://hdl.handle.net/10453/159718
© 2016 The Royal Society of Chemistry. Traumatic brain injury (TBI) is complicated by a sudden and dramatic change in brain metal levels, including iron (Fe), copper (Cu) and zinc (Zn). Specific 'metallo-pathological' features of TBI include increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::b736414caae78615ebab71c30564cdfc
https://hdl.handle.net/10453/41097
https://hdl.handle.net/10453/41097
Autor:
Paul, B, Hare, DJ, Bishop, DP, Paton, C, Nguyen, VT, Cole, N, Niedwiecki, MM, Andreozzi, E, Vais, A, Billings, JL, Bray, L, Bush, AI, McColl, G, Roberts, BR, Adlard, PA, Finkelstein, DI, Hellstrom, J, Hergt, JM, Woodhead, JD, Doble, PA
© The Royal Society of Chemistry 2016. A funder was omitted in the Acknowledgements section and the following text should have been added: This work was also supported by the Ramaciotti Foundation. The Royal Society of Chemistry apologises for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::f63d4ed2ef7194e6ba4335f2cb9705e7
https://hdl.handle.net/10453/132283
https://hdl.handle.net/10453/132283
Autor:
Paul, B, Hare, DJ, Bishop, DP, Paton, C, Nguyen, VT, Cole, N, Niedzwiecki, MM, Andreozzi, E, Vais, A, Billings, JL, Bray, L, Bush, AI, McColl, G, Roberts, BR, Adlard, PA, Finkelstein, DI, Hellstrom, J, Hergt, JM, Woodhead, JD, Doble, PA
© The Royal Society of Chemistry. Correction for 'Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging' by Bence Paul et al., Chem. Sci., 2015, DOI: 10.1039/c5sc0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::2b344c8cff7c8625992377244a680800
https://hdl.handle.net/10453/41100
https://hdl.handle.net/10453/41100
Autor:
Davies, KM, Hare, DJ, Bohic, S, James, SA, Billings, JL, Finkelstein, DI, Doble, PA, Double, KL
© 2015 American Chemical Society. Redox-active metals in the brain mediate numerous biochemical processes and are also implicated in a number of neurodegenerative diseases. A number of different approaches are available for quantitatively measuring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::ab43532051ec7e2894c875a97a865de7
https://hdl.handle.net/10453/36511
https://hdl.handle.net/10453/36511
Autor:
Ayton, S, Lei, P, Hare, DJ, Duce, JA, George, JL, Adlard, PA, McLean, C, Rogers, JT, Cherny, RA, Finkelstein, DI, Bush, AI
© 2015 the authors. Elevation of both neuronal iron and nitric oxide (NO) in the substantia nigra are associated with Parkinson’s disease (PD) pathogenesis. We reported previously that the Alzheimer-associated β-amyloid precursor protein (APP) fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::6c6a997a2b72cc7fda4dada7a12babae
https://hdl.handle.net/10453/35237
https://hdl.handle.net/10453/35237
Autor:
Hare, DJ, Lei, P, Ayton, S, Roberts, BR, Grimm, R, George, JL, Bishop, DP, Beavis, AD, Donovan, SJ, McColl, G, Volitakis, I, Masters, CL, Adlard, PA, Cherny, RA, Bush, AI, Finkelstein, DI, Doble, PA
The co-localization of iron and dopamine raises the risk of a potentially toxic reaction. Disturbance of the balance in this unique chemical environment makes neurons in the substantia nigra pars compacta (SNc) particularly vulnerable to parkinsonian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::633b4bacdee639f1eddf29eea46ecd24
https://hdl.handle.net/10453/3280110453/29630
https://hdl.handle.net/10453/3280110453/29630