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A naturalistic assay for measuring behavioral responses to aversive stimuli at millisecond timescale
We have designed a Virtual Burrow Assay (VBA) to detect the behavioral responses of head-fixed mice to aversive stimuli. We demonstrate its suitability for measuring novelty detection as well as aversion to both conditioned and innately aversive cues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee7f94af47e918384260a5a1664d54b
Autor:
Bauer J; Max Planck Institute for Biological Intelligence, Martinsried, Germany. joel.bauer@ucl.ac.uk.; International Max Planck Research School for Molecular Life Sciences, Martinsried, Germany. joel.bauer@ucl.ac.uk.; Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK. joel.bauer@ucl.ac.uk., Lewin U; Max Planck Institute for Biological Intelligence, Martinsried, Germany.; Graduate School of Systemic Neurosciences, Ludwig-Maximilians-Universität München, Planegg, Germany., Herbert E; School of Life Sciences, Technical University of Munich, Freising, Germany., Gjorgjieva J; School of Life Sciences, Technical University of Munich, Freising, Germany., Schoonover CE; Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, USA.; Allen Institute for Neural Dynamics, Seattle, WA, USA., Fink AJP; Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, USA.; Department of Neurobiology, Northwestern University, Evanston, IL, USA., Rose T; Max Planck Institute for Biological Intelligence, Martinsried, Germany.; Institute for Experimental Epileptology and Cognition Research, University of Bonn, Medical Center, Bonn, Germany., Bonhoeffer T; Max Planck Institute for Biological Intelligence, Martinsried, Germany., Hübener M; Max Planck Institute for Biological Intelligence, Martinsried, Germany. mark.huebener@bi.mpg.de.
Publikováno v:
Nature communications [Nat Commun] 2024 Oct 23; Vol. 15 (1), pp. 9153. Date of Electronic Publication: 2024 Oct 23.
Autor:
Fink AJP; Present affiliation: Department of Neurobiology, Northwestern University, Evanston, IL, United States. Electronic address: af2243@columbia.edu., Hogan M; Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, United States., Schoonover CE; Present affiliation: Allen Institute for Neural Dynamics, Seattle, WA, United States. Electronic address: ces2001@columbia.edu.
Publikováno v:
Neurobiology of learning and memory [Neurobiol Learn Mem] 2024 Sep; Vol. 213, pp. 107951. Date of Electronic Publication: 2024 Jun 04.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 21. Date of Electronic Publication: 2024 Apr 21.
Autor:
Schoonover CE; Zuckerman Institute, Columbia University, New York, NY, United States., Fink AJP; Zuckerman Institute, Columbia University, New York, NY, United States., Poo C; Allen Institute for Neural Dynamics, Allen Institute, Seattle, CA, United States.; Champalimaud Research, Champalimaud Foundation, Lisbon, Portugal., Yuan Q; Division of Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.
Publikováno v:
Frontiers in cellular neuroscience [Front Cell Neurosci] 2023 Feb 02; Vol. 17, pp. 1146770. Date of Electronic Publication: 2023 Feb 02 (Print Publication: 2023).
Autor:
Schoonover CE; Howard Hughes Medical Institute, Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, USA. ces2001@columbia.edu., Ohashi SN; Howard Hughes Medical Institute, Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, USA.; Immunobiology Graduate Program, Yale School of Medicine, New Haven, CT, USA., Axel R; Howard Hughes Medical Institute, Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, USA. ra27@columbia.edu., Fink AJP; Howard Hughes Medical Institute, Mortimer B. Zuckerman Mind Brain Behavior Institute, Department of Neuroscience, Columbia University, New York, NY, USA. af2243@columbia.edu.
Publikováno v:
Nature [Nature] 2021 Jun; Vol. 594 (7864), pp. 541-546. Date of Electronic Publication: 2021 Jun 09.