Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Findeiß, Sven"'
Long non-coding RNAs (lncRNAs) are widely recognized as important regulators of gene expression. Their molecular functions range from miRNA sponging to chromatin-associated mechanisms, leading to effects in disease progression and establishing them a
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https://ul.qucosa.de/id/qucosa%3A85302
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https://ul.qucosa.de/api/qucosa%3A85302/attachment/ATT-0/
We describe a synthetic riboswitch element that implements a regulatory principle which directly addresses an essential tRNA maturation step. Constructed using a rational in silico design approach, this riboswitch regulates RNase P-catalyzed tRNA 5'-
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A78047
https://ul.qucosa.de/api/qucosa%3A78047/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A78047/attachment/ATT-0/
Autor:
Domin, Gesine, Findeiß, Sven, Wachsmuth, Manja, Will, Sebastian, Stadler, Peter F., Mörl, Mario
Publikováno v:
Nucleic Acids Research, 2016 doi: 10.1093/nar/gkw1267
Riboswitches have gained attention as tools for synthetic biology, since they enable researchers to reprogram cells to sense and respond to exogenous molecules. In vitro evolutionary approaches produced numerous RNA aptamers that bind such small liga
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A15259
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https://ul.qucosa.de/api/qucosa%3A15259/attachment/ATT-0/
The EGF-TM7 receptor CD97 shows different features of expression and function in muscle cells compared to hematopoetic and tumor cells. Since the molecular function and regulation of CD97 are poorly understood, this study aimed at defining its basal
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31891
https://ul.qucosa.de/api/qucosa%3A31891/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31891/attachment/ATT-0/
Autor:
Rose, Dominic, Hackermüller, Jörg, Washietl, Stefan, Reiche, Kristin, Hertel, Jana, Findeiß, Sven, Stadler, Peter F., Prohaska, Sonja J.
Recent experimental and computational studies have provided overwhelming evidence for a plethora of diverse transcripts that are unrelated to protein-coding genes. One subclass consists of those RNAs that require distinctive secondary structure motif
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A31952
https://ul.qucosa.de/api/qucosa%3A31952/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A31952/attachment/ATT-0/
Artificial RNA molecules with novel functionality have many applications in synthetic biology, pharmacy and white biotechnology. The de novo design of such devices using computational methods and prediction tools is a resource-efficient alternative t
Externí odkaz:
http://arxiv.org/abs/1902.01143
Autor:
Findeiß, Sven
The detection of non-protein-coding RNA (ncRNA) genes in bacteria and their diverse regulatory mode of action moved the experimental and bio-computational analysis of ncRNAs into the focus of attention. Regulatory ncRNA transcripts are not translated
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A11159
https://ul.qucosa.de/api/qucosa%3A11159/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A11159/attachment/ATT-0/
Autor:
Klapproth, Christopher, Zötzsche, Siegfried, Kühnl, Felix, Fallmann, Jörg, Stadler, Peter F, Findeiß, Sven
Publikováno v:
NAR Genomics & Bioinformatics; Sep2023, Vol. 5 Issue 3, p1-16, 16p
This report documents the program and outcomes of Dagstuhl Seminar 22381 "Rational Design of RiboNucleic Acids" (RNAs). The seminar covered a wide array of models, algorithmic strategies, molecular scales and modalities, all targeting in silico desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b60d8175266be21456fd0c5e3d9c93fe
Autor:
Müller, Stephan A., Findeiß, Sven, Pernitzsch, Sandy R., Wissenbach, Dirk K., Stadler, Peter F., Hofacker, Ivo L., von Bergen, Martin, Kalkhof, Stefan
Publikováno v:
In Journal of Proteomics 28 June 2013 86:27-42