Identification of a thalidomide derivative that selectively targets tumorigenic liver progenitor cells and comparing its effects with lenalidomide and sorafenib

Autor: Woo, Ken, Stewart, Scott G., Kong, Geraldine S., Finch-Edmondson, Megan L., Dwyer, Benjamin J., Yeung, Sing Y., Abraham, Lawrence J., Kampmann, Sven S., Diepeveen, Luke A., Passman, Adam M., Elsegood, Caryn L., Tirnitz-Parker, Janina E.E., Callus, Bernard A., Olynyk, John K., Yeoh, George C.T.

Publikováno v: In European Journal of Medicinal Chemistry 14 September 2016 120:275-283

Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins.

Autor: Goodall, Katharine J.¹ katharine.goodall@monash.edu, Finch-Edmondson, Megan L.², van Vuuren, Joanne³, Yeoh, George C.^2,3, Gentle, Ian E.^1,4, Vince, James E.^1,5,6, Ekert, Paul G.^1,5,7, Vaux, David L.^1,5,6, Callus, Bernard A.^1,2,8

Publikováno v: PLoS ONE. 11/2/2016, Vol. 11 Issue 11, p1-18. 18p.

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Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.

Autor: Verma A; Department of Biological Sciences, National University of Singapore, Singapore., Jing-Song F; Department of Biological Sciences, National University of Singapore, Singapore., Finch-Edmondson ML; Mechanobiology Institute, National University of Singapore, Singapore., Velazquez-Campoy A; Institute of Biocomputation and Physics of Complex Systems (BIFI)-Joint Units: BIFI-IQFR (CSIC) and GBsC-CSIC, Universidad de Zaragoza, Spain, Department of Biochemistry and Molecular and Cellular Biology, Universidad de Zaragoza, Fundacion ARAID, Gobierno de Aragon, Spain, Aragon Health Research Institute (IIS Aragon), Universidad de Zaragoza, Zaragoza, Spain., Balasegaran S; Department of Biological Sciences, National University of Singapore, Singapore., Sudol M; Mechanobiology Institute, National University of Singapore, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, MD9, Singapore.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research, Singapore., Sivaraman J; Department of Biological Sciences, National University of Singapore, Singapore.

Publikováno v: Oncotarget [Oncotarget] 2018 Jan 03; Vol. 9 (8), pp. 8068-8080. Date of Electronic Publication: 2018 Jan 03 (Print Publication: 2018).