Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Filomena G. Ottaviano"'
Autor:
Anthony Rosenzweig, Ling Xiao, Santosh Khedkar, Vassilios J. Bezzerides, Aifeng Zhang, Filomena G. Ottaviano, David J. Milan, Shiro Baba, Stacey N. Lynch, Saumya Das, Alan C. Rigby, Katherine Hessler, Bridget Simonson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Alterations in sodium flux (INa) play an important role in the pathogenesis of cardiac arrhythmias and may also contribute to the development of cardiomyopathies. We have recently demonstrated a critical role for the regulation of the voltage-gated s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed646555a542b20a210e46e21b0b9f26
Autor:
Filomena G. Ottaviano, Tejvir S. Khurana, Ionita Ghiran, Bridget Simonson, Vinita Subramanya, Maria I. Kontaridis, Danielle Hunt, Hannabeth Franchino, Ashley C. Knight, Saumya Das, Mun Chun Chan, Aifeng Zhang, Manoj K. Mishra, Anthony Rosenzweig
Publikováno v:
Science signaling. 10(468)
Physiological cardiac hypertrophy, in response to stimuli such as exercise, is considered adaptive and beneficial. In contrast, pathological cardiac hypertrophy that arises in response to pathological stimuli such as unrestrained high blood pressure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ee92b72fe569994dded9de271e8f54
https://pubmed.ncbi.nlm.nih.gov/28246202
https://pubmed.ncbi.nlm.nih.gov/28246202
Autor:
Filomena G. Ottaviano, Joseph Loscalzo, Jane A. Leopold, Christopher E Mahoney, Diane E. Handy, Kevin Croce, Richard C Jin, Shiow-Shih Tang, Ying-Yi Zhang, Laura Coleman Anderson
Publikováno v:
Circulation. 123:1963-1973
Background— Glutathione peroxidase-3 (GPx-3) is a selenocysteine-containing plasma protein that scavenges reactive oxygen species in the extracellular compartment. A deficiency of this enzyme has been associated with platelet-dependent thrombosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf954987a87bf02889fea156b9a5f91
https://doi.org/10.1161/circulationaha.110.000034
https://doi.org/10.1161/circulationaha.110.000034
Autor:
Filomena G. Ottaviano, Karen O Yee
Publikováno v:
Journal of Cardiovascular Pharmacology. 57:513-521
Interspersed between cardiac myocytes, cardiac fibroblasts serve mainly as a structural support during ventricular wall thickening from embryogenesis until adulthood. Cardiac fibroblasts, however, may also serve as a source of mitogens, extracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b1870731c1ff26099d749e4de7249f
https://doi.org/10.1097/fjc.0b013e31821209ee
https://doi.org/10.1097/fjc.0b013e31821209ee
Publikováno v:
Circulation Journal. 72:1-16
The oxidizing nature of the extracellular environment is vastly different from the highly reducing nature of the intracellular compartment. The redox potential of the cytosolic compartment of the intracellular environment limits disulfide bond format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f098ae509b685d5cbb4afe0a1d73426
https://doi.org/10.1253/circj.72.1
https://doi.org/10.1253/circj.72.1
Autor:
Saumya Das, Gordon F. Tomaselli, Michael A. Rosenberg, Filomena G. Ottaviano, Katherine Hessler, Patrick T. Ellinor, Michael J. Begley, Ashley C. Knight, Anthony Rosenzweig, Federica del Monte, Takeshi Aiba, Chunyang Xiao, Pablo A. Quintero, Pontus Boström, Lewis C. Cantley, Evan L. Graham, Michael R. Morissette
Publikováno v:
Circulation. 126(18)
Background— Heart failure is a growing cause of morbidity and mortality. Cardiac phosphatidylinositol 3-kinase signaling promotes cardiomyocyte survival and function, but it is paradoxically activated in heart failure, suggesting that chronic activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee193b8291f6d0a7afb94389fdae23e
https://pubmed.ncbi.nlm.nih.gov/23019295
https://pubmed.ncbi.nlm.nih.gov/23019295
Publikováno v:
The FASEB Journal. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66430ed64203a95a4d659161576fb191
https://doi.org/10.1096/fasebj.23.1_supplement.500.1
https://doi.org/10.1096/fasebj.23.1_supplement.500.1
Plasma glutathione peroxidase (GPx-3) is a selenocysteine-containing extracellular antioxidant protein that catalyzes the reduction of hydrogen peroxide and lipid hydroperoxides. Selenoprotein expression involves the alternate recognition of a UGA co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbbd7ef99bb54ce046922cf17fcb47f
https://europepmc.org/articles/PMC2693281/
https://europepmc.org/articles/PMC2693281/
Autor:
Richard C Jin, Christopher E Mahoney, Laura Coleman, Filomena G Ottaviano, Yingyi Zhang, Diane E Handy, Joseph Loscalzo
Publikováno v:
Circulation. 118
Plasma glutathione peroxidase (GPx-3) is a selenocysteine-containing protein with antioxidant properties. GPx-3 plays an important role in plasma against oxidant stress by scavenging reactive oxygen species. A deficiency of this enzyme has been assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0692223e9add5f88f52a4dd2fbc2d75b
https://doi.org/10.1161/circ.118.suppl_18.s_552
https://doi.org/10.1161/circ.118.suppl_18.s_552
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec94159837c192c931be3d711f634c2d
https://doi.org/10.1096/fasebj.22.1_supplement.998.2
https://doi.org/10.1096/fasebj.22.1_supplement.998.2