VGF Protein and Its C-Terminal Derived Peptides in Amyotrophic Lateral Sclerosis: Human and Animal Model Studies.

Autor: Carla Brancia, Barbara Noli, Marina Boido, Andrea Boi, Roberta Puddu, Giuseppe Borghero, Francesco Marrosu, Paolo Bongioanni, Sandro Orrù, Barbara Manconi, Filomena D'Amato, Irene Messana, Federica Vincenzoni, Alessandro Vercelli, Gian-Luca Ferri, Cristina Cocco

Publikováno v: PLoS ONE, Vol 11, Iss 10, p e0164689 (2016)

VGF mRNA is widely expressed in areas of the nervous system known to degenerate in Amyotrophic Lateral Sclerosis (ALS), including cerebral cortex, brainstem and spinal cord. Despite certain VGF alterations are reported in animal models, little inform

Externí odkaz: https://doaj.org/article/ad59cfc36a4b4c04b1e1dfb9201ae777

VGF Peptide Profiles in Type 2 Diabetic Patients' Plasma and in Obese Mice.

Autor: Filomena D'Amato, Barbara Noli, Laura Angioni, Efisio Cossu, Michela Incani, Irene Messana, Barbara Manconi, Paola Solinas, Raffaella Isola, Stefano Mariotti, Gian-Luca Ferri, Cristina Cocco

Publikováno v: PLoS ONE, Vol 10, Iss 11, p e0142333 (2015)

To address the possible involvement of VGF peptides in obesity and diabetes, we studied type 2 diabetes (T2D) and obese patients, and high-fat diet induced obese mice. Two VGF peptides (NAPP-19 and QQET-30) were identified in human plasma by HPLC-ESI

Externí odkaz: https://doaj.org/article/763b6b7efbd24541b02e51dc21e91f8f

BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers

Autor: Fabio Pisano, Marialuisa Lavitrano, Gian-Luca Ferri, Filomena D'Amato, Emile E. Voest, Marco Agostini, Sara Bonomo, Annamaria Cialdella, Carola Missaglia, Gabriele Romano, Maria Grazia Cerrito, Kristian Helin, Roberto Giovannoni, Emanuela Grassilli, Vincenzo Canzonieri, Biagio Eugenio Leone, Barbara Noli, Leonarda Ianzano, Salvatore Pucciarelli, Chelsea M. McLean

Colorectal cancer (CRC) is the fourth cause of death from cancer worldwide mainly due to the high incidence of drug-resistance. During a screen for new actionable targets in drug-resistant tumours we recently identified p65BTK–a novel oncogenic iso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5625689a21da4b1f879095e8bd621c3a
http://hdl.handle.net/10281/242487

Profiles of VGF Peptides in the Rat Brain and Their Modulations after Phencyclidine Treatment

Autor: Maria Rosaria Melis, Carla Brancia, Fabrizio Sanna, Antonio Argiolas, Barbara Manconi, Filomena D'Amato, Cristina Cocco, Barbara Noli, Gian-Luca Ferri, Federica Vincenzoni, I Messana

Publikováno v: Frontiers in Cellular Neuroscience, Vol 11 (2017)
Frontiers in cellular neuroscience 11 (2017). doi:10.3389/fncel.2017.00158
info:cnr-pdr/source/autori:Noli, Barbara; Sanna, Fabrizio; Brancia, Carla; D'Amato, Filomena; Manconi, Barbara; Vincenzoni, Federica; Messana, Irene; Melis, Maria R.; Argiolas, Antonio; Ferri, Gian-Luca; Cocco, Cristina/titolo:Profiles of VGF Peptides in the Rat Brain and Their Modulations after Phencyclidine Treatment/doi:10.3389%2Ffncel.2017.00158/rivista:Frontiers in cellular neuroscience/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Frontiers in Cellular Neuroscience

From the VGF precursor protein originate several low molecular weight peptides, whose distribution in the brain and blood circulation is not entirely known. Among the VGF peptides, those containing the N-terminus portion were altered in the cerebro-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b79256e5cf222f80c6f7e6961fe91b
https://doi.org/10.3389/fncel.2017.00158

VGF Protein and Its C-Terminal Derived Peptides in Amyotrophic Lateral Sclerosis: Human and Animal Model Studies

Autor: Sandro Orru, Barbara Manconi, Alessandro Vercelli, Giuseppe Borghero, Francesco Marrosu, Marina Boido, Filomena D'Amato, Paolo Bongioanni, Cristina Cocco, Roberta Puddu, Irene Messana, Andrea Boi, Barbara Noli, Carla Brancia, Gian-Luca Ferri, Federica Vincenzoni

Publikováno v: PLoS ONE
PloS one 11 (2016). doi:10.1371/journal.pone.0164689
info:cnr-pdr/source/autori:Brancia, Carla; Noli, Barbara; Boido, Marina; Boi, Andrea; Puddu, Roberta; Borghero, Giuseppe; Marrosu, Francesco; Bongioanni, Paolo; Orru, Sandro; Manconi, Barbara; D'Amatol, Filomena; Messana, Irene; Vincenzoni, Federica; Vercelli, Alessandro; Ferri, Gian-Luca; Cocco, Cristina/titolo:VGF Protein and Its C-Terminal Derived Peptides in Amyotrophic Lateral Sclerosis: Human and Animal Model Studies/doi:10.1371%2Fjournal.pone.0164689/rivista:PloS one/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
PLoS ONE, Vol 11, Iss 10, p e0164689 (2016)

VGF mRNA is widely expressed in areas of the nervous system known to degenerate in Amyotrophic Lateral Sclerosis (ALS), including cerebral cortex, brainstem and spinal cord. Despite certain VGF alterations are reported in animal models, little inform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e681daba1dd01c3a0311bac198dff4
http://europepmc.org/articles/PMC5063282